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CPT code 59000: Amniocentesis, diagnostic fluid sampling2026 Medicare rate & RVUs in Alabama

Percutaneous amniotic fluid collection for prenatal diagnostic testing, such as evaluation of fetal chromosomes, genetic conditions, or infection.

CMS RVU26DEffective Oct 1, 2026One payment locality59 Medicare services in 2024

In Alabama, Medicare pays $105.70 for 59000 in the office and $64.78 when it’s performed in a hospital or facility.

$105.70Office (non-facility)
$64.78Hospital or facility
−11.6%vs the national office rate ($119.58)

Check a contract rate as a % of Medicare · 59000 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 59000 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Alabama
  2. What 59000 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 59000 covers

An obstetrician or maternal-fetal medicine specialist uses a needle passed through the maternal abdomen and uterine wall to collect amniotic fluid. Ultrasound commonly helps locate the fluid pocket and avoid the fetus and placenta. The sample is sent for diagnostic laboratory testing, such as chromosome or genetic analysis or evaluation for fetal infection. The procedure is performed in an office or facility setting where prenatal diagnostic sampling is provided.

Report 59000 for diagnostic fluid collection, not for fluid removal intended to treat a condition. The record should identify the diagnostic indication, the sampling procedure, and the specimen obtained; laboratory analysis is separately represented. This minor procedure has a 0-day global period, so same-day preoperative and postoperative care is included. When multiple procedures occur in the same session, the highest-valued procedure is paid in full and the others are subject to the standard 50% reduction. Modifier 50 is inappropriate. Medicare does not pay an assistant at surgery for this service; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Alabama compares for 59000

Across 109 of 109 payment localities, the office rate for 59000 runs from $103.99 in Arkansas to $146.02 in NYC suburbs and Long Island, NY. Alabama pays $105.70. The RVUs are the same everywhere; the geographic indexes change the dollars.

59000 in Alabama vs other payment areas
  1. Alabama · this page$105.70
  2. Los Angeles, CA · California$128.33+$22.63
  3. Washington, DC area · District of Columbia$134.71+$29.01
  4. Miami, FL · Florida$143.12+$37.42
  5. Chicago, IL · Illinois$137.92+$32.22
  6. Manhattan, NY · New York$140.60+$34.90
  7. Alaska · Alaska$138.76+$33.06

Other areas in Alabama first, then benchmark localities. Bars start at $0.

Every other payment area

59000 in every other Medicare payment locality
Payment localityOfficeFacility
ArkansasArkansas$103.99$63.82
ArizonaArizona$115.64$70.32
Bakersfield, CACalifornia$121.12$69.87
Chico, CACalifornia$120.03$68.78
El Centro, CACalifornia$120.10$68.85
Fresno, CACalifornia$120.03$68.78
Hanford, CACalifornia$120.03$68.78
Madera, CACalifornia$120.03$68.78

59000 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$103.99

$138.76

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
59000 office rate range by state
State / territoryOffice rate rangeLocalities
AK$138.761
AL$105.701
AR$103.991
AZ$115.641
CA$120.03–$145.9429
CO$121.151
CT$128.191
DC$134.711
DE$117.641
FL$123.67–$143.123
GA$115.35–$123.472
GU$122.501
HI$122.501
IA$105.921
ID$107.281
IL$121.76–$137.924
IN$107.901
KS$106.691
KY$111.371
LA$111.70–$117.692
MA$120.84–$132.122
MD$119.64–$134.713
ME$109.32–$113.952
MI$115.82–$126.752
MN$111.771
MO$110.46–$116.563
MS$107.181
MT$119.551
NC$110.381
ND$111.441
NE$106.171
NH$120.471
NJ$128.44–$133.332
NM$117.061
NV$117.351
NY$112.33–$146.025
OH$114.161
OK$109.731
OR$115.25–$123.792
PA$113.62–$125.582
PR$120.071
RI$121.001
SC$112.701
SD$110.481
TN$107.461
TX$112.89–$124.628
UT$114.371
VA$114.47–$134.712
VI$120.071
VT$112.181
WA$120.22–$133.602
WI$107.431
WV$117.161
WY$116.011

See 59000 in every payment locality

How the 59000 rate is calculated

Each of 59000’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 59000

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.27

1.27 RVUs× 1.000 GPCI

Practice expense1.90

1.90 RVUs× 1.000 GPCI

Malpractice0.41

0.41 RVUs× 1.000 GPCI

Adjusted RVUs

3.5800

Conversion factor

$33.4009

Medicare rate

$119.58

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Alabama inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

6,624

Code
59000
Physician work
1.27
Practice expense
1.90
Malpractice
0.41

GPCI2026.csv

4

Locality
Alabama
Physician work
1.000
Practice expense
0.875
Malpractice
0.566
Office calculation for 59000 in Alabama
ComponentRVULocality factorAdjusted
Physician work1.27× 1.0001.2700
Practice expense1.90× 0.8751.6625
Malpractice0.41× 0.5660.2321
Total RVUs3.1646
Conversion factor× 33.4009

Office rate, Alabama$105.70

Office: (1.27 × 1 + 1.9 × 0.875 + 0.41 × 0.566) × $33.4009 = $105.70

Facility: (1.27 × 1 + 0.5 × 0.875 + 0.41 × 0.566) × $33.4009 = $64.78

Open 59000 in the RVU calculator

Payment rules and modifiers for 59000

The CMS indicators that decide how 59000 is paid alongside other services.

CMS payment indicators · 59000

Amniocentesis, diagnostic fluid sampling

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

59000 without 51 · national office

$119.58

Amniocentesis, diagnostic fluid sampling

59000-51 · Second procedure: 50%

$59.79

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

Codes related to 59000

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 59000
CodeHow it relatesOffice range, Alabama
Used instead
59001Amniocentesis, therapeutic fluid reductionAmniotic fluid removal for therapeutic purposes rather than diagnostic sampling.No office rate
59015Chorionic villus sampling, placental tissue samplingPrenatal diagnostic sampling using chorionic tissue instead of amniotic fluid.$142.53
59012Cordocentesis, prenatal fetal blood samplingPrenatal sampling through fetal cord puncture rather than amniotic fluid collection.No office rate
Often billed with
76946Amniocentesis guidance, ultrasound needle guidanceUltrasound guidance for amniocentesis may be reported with the sampling service.$31.05

How 59000 has changed in Alabama

59000 · Office / nonfacility

$105.70

Effective 2026-10-01

The base rate is $4.11 higher than on 2025-10-01, moving from $101.59 to $105.70 (4.0%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $101.59changed to$105.70

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.30 changed to 1.27
    • Practice expense RVU 1.86 changed to 1.90
    • Malpractice RVU 0.39 changed to 0.41
    • Practice expense GPCI 0.869 changed to 0.875
    • Malpractice GPCI 0.575 changed to 0.566

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $105.02changed to$101.59

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 1.87 changed to 1.86
    • Malpractice RVU 0.40 changed to 0.39

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $103.31changed to$105.02

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $108.43changed to$103.31

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 1.84 changed to 1.87
    • Malpractice RVU 0.38 changed to 0.40
    • Practice expense GPCI 0.878 changed to 0.869
    • Malpractice GPCI 0.748 changed to 0.575

  5. January 1, 2023

    RVU23A

    $111.79changed to$108.43

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 1.79 changed to 1.84
    • Malpractice RVU 0.37 changed to 0.38
    • Practice expense GPCI 0.888 changed to 0.878
    • Malpractice GPCI 0.921 changed to 0.748

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $113.61changed to$111.79

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 1.85 changed to 1.79
    • Malpractice RVU 0.34 changed to 0.37

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $114.24changed to$113.61

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 1.82 changed to 1.85
    • Malpractice RVU 0.35 changed to 0.34
    • Practice expense GPCI 0.889 changed to 0.888
    • Malpractice GPCI 0.707 changed to 0.921

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $113.50changed to$114.24

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 1.89 changed to 1.82
    • Malpractice RVU 0.34 changed to 0.35
    • Practice expense GPCI 0.890 changed to 0.889
    • Malpractice GPCI 0.492 changed to 0.707

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $116.23changed to$113.50

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 1.99 changed to 1.89
    • Malpractice RVU 0.32 changed to 0.34

    Held through RVU19B, RVU19C, RVU19D.

  10. April 1, 2018

    RVU18B

    No ratechanged to$116.23

    Held through RVU18C, RVU18D.

  11. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$105.70$64.78RVU26D
2026-07-01$105.70$64.78RVU26C
2026-04-01$105.70$64.78RVU26B
2026-01-01$105.70$64.78RVU26A
2025-10-01$101.59$69.82RVU25D
2025-07-01$101.59$69.82RVU25C
2025-04-01$101.59$69.82RVU25B
2025-01-01$101.59$69.82RVU25A
2024-10-01$105.02$72.05RVU24D
2024-07-01$105.02$72.05RVU24C
2024-04-01$105.02$72.05RVU24B
2024-03-09$105.02$72.05RVU24AR
2024-01-01$103.31$70.87RVU24A
2023-10-01$108.43$75.11RVU23D
2023-07-01$108.43$75.11RVU23C
2023-04-01$108.43$75.11RVU23B
2023-01-01$108.43$75.11RVU23A
2022-10-01$111.79$77.98RVU22D
2022-07-01$111.79$77.98RVU22C
2022-04-01$111.79$77.98RVU22B
2022-01-01$111.79$77.98RVU22A
2021-10-01$113.61$77.67RVU21D
2021-07-01$113.61$77.67RVU21C
2021-04-01$113.61$77.67RVU21B
2021-01-01$113.61$77.67RVU21A
2020-10-01$114.24$77.66RVU20D
2020-07-01$114.24$77.66RVU20C
2020-04-01$114.24$77.66RVU20B
2020-01-01$114.24$77.66RVU20A
2019-10-01$113.50$75.01RVU19D
2019-07-01$113.50$75.01RVU19C
2019-04-01$113.50$75.01RVU19B
2019-01-01$113.50$75.01RVU19A
2018-10-01$116.23$74.90RVU18D
2018-07-01$116.23$74.90RVU18C
2018-04-01$116.23$74.90RVU18B
2018-01-01Rate data unavailableRate data unavailableRVU18AR1
2017-10-01Rate data unavailableRate data unavailableRVU17D
2017-07-01Rate data unavailableRate data unavailableRVU17C
2017-04-01Rate data unavailableRate data unavailableRVU17B
2017-01-01Rate data unavailableRate data unavailableRVU17A
2016-10-01Rate data unavailableRate data unavailableRVU16D
2016-07-01Rate data unavailableRate data unavailableRVU16C
2016-04-01Rate data unavailableRate data unavailableRVU16B
2016-01-01Rate data unavailableRate data unavailableRVU16A
2015-10-01Rate data unavailableRate data unavailableRVU15D
2015-07-01Rate data unavailableRate data unavailableRVU15C
2015-04-01Rate data unavailableRate data unavailableRVU15B
2015-01-01Rate data unavailableRate data unavailableRVU15A
2014-10-01Rate data unavailableRate data unavailableRVU14D
2014-07-01Rate data unavailableRate data unavailableRVU14C
2014-04-01Rate data unavailableRate data unavailableRVU14B
2014-01-01Rate data unavailableRate data unavailableRVU14A
2013-10-01Rate data unavailableRate data unavailableRVU13D
2013-07-01Rate data unavailableRate data unavailableRVU13C
2013-04-01Rate data unavailableRate data unavailableRVU13B
2013-01-01Rate data unavailableRate data unavailableRVU13AR

Price 59000 for an earlier date of service

Where the Alabama rate applies

Alabama is a Medicare payment area, not a city. Our Census mapping connects it to 595 cities and communities in Alabama. Some span more than one payment area; confirm with the service ZIP.

  • Abanda
  • Abbeville
  • Adamsville
  • Addison
  • Akron
  • Alabaster
  • Albertville
  • Alexander City

Browse all communities in Alabama

59000 billing questions

How does 59000 differ from therapeutic amniocentesis?

Use 59000 when fluid is collected for diagnosis. Code 59001 describes amniotic fluid removal for a therapeutic purpose.

Is ultrasound guidance included in 59000?

Ultrasound is commonly used to guide needle placement. When guidance is performed and documented, 76946 may be reported separately, subject to applicable coding edits.

Can modifier 50 be used for sampling from both sides?

No. The CMS bilateral adjustment does not apply, and modifier 50 is inappropriate for this service.

Can an assistant or co-surgeon be reported?

Medicare does not pay an assistant at surgery for 59000. Co-surgeons and team surgery are not permitted.

What documentation supports reporting 59000?

Document the diagnostic reason for sampling, the amniocentesis performed, and the fluid specimen obtained. Keep the diagnostic purpose distinct from therapeutic fluid removal.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 59000PPRRVU2026_Oct_nonQPP.csv, line 6,624 (RVU26D)
Geographic factors for AlabamaGPCI2026.csv, line 4 (RVU26D)

Open CMS sourceHow we calculate rates

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