CPT code 64408: Vagus nerve block, anesthetic injection2026 Medicare rate & RVUs

Injection of anesthetic around the vagus nerve for a diagnostic or therapeutic block, including selected vagal sensory blocks for neurogenic cough.

CMS RVU26DEffective Oct 1, 2026109 payment localities2.3K Medicare services in 2024

Medicare pays $79.83 for 64408 nationally in the office and $38.75 in a hospital or facility. Local office rates run $70.75–$103.69.

Medicare rate · 64408

Vagus nerve block, anesthetic injection

Office or facility?

Work RVUs
0.73
Total RVUs
2.39
Global days
000

National rate · 2026

$79.83

Office setting, before claim adjustments.

See every locality for 64408 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What 64408 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 64408 covers

This service places anesthetic at the vagus nerve to interrupt or assess nerve-mediated symptoms. A recognized clinical use is a vagal sensory block, including a superior laryngeal nerve block, for selected patients with neurogenic cough. Pain physicians, anesthesiologists, and otolaryngologists may perform the injection in an office or procedural setting; the record should identify the nerve target, side, indication, and technique.

Select 64408 when the documented target is the vagus nerve, rather than another named nerve or an unspecified peripheral nerve. The code has a 0-day global period, so same-day preoperative and postoperative care is included. When multiple procedures occur in the same session, the highest-valued procedure is paid in full and the others at 50%. For bilateral treatment, modifier 50 is paid at 150%. Assistant-at-surgery payment requires documented medical necessity; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 64408 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$70.75 to $103.69

$70.75$87.22$103.69
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

64408 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$71.76$35.81
Alaska$93.73$49.98
Arizona$77.69$37.88
Arkansas$70.75$35.46
Atlanta, GA$81.47$39.73
Austin, TX$82.46$38.99
Bakersfield, CA$83.82$38.80
Baltimore area, MD$84.87$40.79
Beaumont, TX$74.91$37.52
Brazoria, TX$78.75$38.04

64408 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$70.75

$93.73

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
64408 office rate range by state
State / territoryOffice rate rangeLocalities
AK$93.731
AL$71.761
AR$70.751
AZ$77.691
CA$83.51–$103.6929
CO$82.631
CT$85.071
DC$90.781
DE$78.961
FL$79.40–$87.573
GA$74.94–$81.472
GU$85.371
HI$85.371
IA$73.211
ID$73.751
IL$77.39–$85.024
IN$74.161
KS$73.041
KY$73.771
LA$73.72–$77.272
MA$82.22–$90.472
MD$80.39–$90.783
ME$74.30–$78.012
MI$75.80–$80.542
MN$78.741
MO$72.59–$77.353
MS$71.671
MT$79.821
NC$75.031
ND$77.651
NE$73.561
NH$81.491
NJ$85.92–$89.902
NM$76.271
NV$79.271
NY$76.15–$94.325
OH$75.351
OK$73.471
OR$78.53–$85.022
PA$75.38–$83.102
PR$80.341
RI$81.601
SC$75.341
SD$77.391
TN$73.421
TX$74.91–$82.468
UT$76.351
VA$77.87–$90.782
VI$80.341
VT$77.501
WA$82.01–$92.132
WI$75.111
WV$74.631
WY$78.871

How the 64408 rate is calculated

Each of 64408’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 64408

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.73

0.73 RVUs× 1.000 GPCI

Practice expense1.55

1.55 RVUs× 1.000 GPCI

Malpractice0.11

0.11 RVUs× 1.000 GPCI

Adjusted RVUs

2.3900

Conversion factor

$33.4009

Medicare rate

$79.83

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 64408

The CMS indicators that decide how 64408 is paid alongside other services.

CMS payment indicators · 64408

Vagus nerve block, anesthetic injection

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)1Bilateral with modifier 50 pays 150% of the fee schedule amount.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 50 · payment effect

With and without the modifier

64408 without 50 · national office

$79.83

Vagus nerve block, anesthetic injection

64408-50 · Bilateral: 150%

$119.75

Both sides on one line with modifier 50 are paid at 150% of the fee schedule amount (subject to multiple-procedure rules with other procedures).

When to use modifier 50

64408 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 64408

    Vagus nerve block, anesthetic injection0.73 wRVU

    $79.83

  • 64400

    Nerve block, trigeminal nerve or branch0.73 wRVU

    $121.91+$42.08

  • 64405

    Occipital nerve block, greater occipital nerve0.92 wRVU

    $78.83−$1.00

  • 64450

    Nerve block, other peripheral nerve or branch0.73 wRVU

    $80.83+$1.00

How to choose

64400Nerve blockTrigeminal nerve or branch
64400 identifies a trigeminal nerve injection, used for a cranial nerve target in the trigeminal distribution. Choose 64408 when the documented target is the vagus nerve.
64405Occipital nerve blockGreater occipital nerve
64405 is specific to the greater occipital nerve. It is not interchangeable with a block directed at the vagus nerve.
64450Nerve blockOther peripheral nerve or branch
64450 is for an other peripheral nerve or branch without a more specific code. Use 64408 when the vagus nerve is the documented target.

64408 billing questions

When should 64408 be selected instead of 64450?

Use 64408 when the documented injection target is the vagus nerve. Code 64450 describes an injection of an other peripheral nerve or branch when a more specific code does not identify the target.

Can 64408 be reported for a neurogenic cough block?

It may describe a vagal sensory block, including a superior laryngeal nerve block, when the documentation identifies the vagal target and supports the service performed.

How is bilateral treatment reported?

When the vagus nerve is treated bilaterally, report modifier 50; CMS pays the bilateral procedure at 150%.

What same-day care is included?

The 0-day global period includes same-day preoperative and postoperative care. Services on a different date are not covered by that same-day global period.

How does CMS handle another procedure performed in the same session?

Under the standard multiple procedure reduction, the highest-valued procedure is paid in full and other procedures are paid at 50%.

Can an assistant or co-surgeon be reported?

Assistant-at-surgery payment is available only with documentation of medical necessity. Co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 64408PPRRVU2026_Oct_nonQPP.csv, line 7,098 (RVU26D)

Open CMS sourceHow we calculate rates

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