CPT code 64646: Muscle chemodenervation, trunk, one to five muscles2026 Medicare rate & RVUs in Minnesota

Reports botulinum toxin chemodenervation of one to five trunk muscles to manage focal muscle overactivity, such as truncal spasticity or dystonia.

CMS RVU26DEffective Oct 1, 2026One payment locality9.7K Medicare services in 2024

In Minnesota, Medicare pays $161.83 for 64646 in the office and $93.43 when it’s performed in a hospital or facility.

$161.83Office (non-facility)
$93.43Hospital or facility
−5.0%vs the national office rate ($170.34)

Check a contract rate as a % of Medicare · 64646 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 64646 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Minnesota
  2. What 64646 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 64646 covers

A clinician injects a chemodenervating agent, commonly botulinum toxin, into one to five trunk muscles to reduce focal overactivity. Neurologists, physiatrists, and other clinicians who treat spasticity or dystonia may perform the service in an office or outpatient procedure setting. Trunk targets can include paraspinal or abdominal muscles; this code is not for injections into limb muscles or eccrine glands.

Select the code by the number of distinct trunk muscles treated during the session, not by the number of injection sites or toxin units. Document the treated muscles, clinical indication, and injection details. Use the six-or-more-muscle trunk code when that threshold is reached. The service has a 0-day global period, so same-day preoperative and postoperative care is included. When multiple procedures occur in one session, the highest-valued procedure is paid in full and others at 50%. Modifier 50 is inappropriate. Assistant-at-surgery payment is statutorily restricted; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Minnesota compares for 64646

Across 109 of 109 payment localities, the office rate for 64646 runs from $149.10 in Arkansas to $211.59 in San Benito County, CA. Minnesota pays $161.83. The RVUs are the same everywhere; the geographic indexes change the dollars.

64646 in Minnesota vs other payment areas
  1. Minnesota · this page$161.83
  2. Los Angeles, CA · California$184.85+$23.02
  3. Washington, DC area · District of Columbia$192.33+$30.50
  4. Miami, FL · Florida$198.77+$36.94
  5. Chicago, IL · Illinois$192.00+$30.17
  6. Manhattan, NY · New York$198.98+$37.15
  7. Alaska · Alaska$198.75+$36.92

Other areas in Minnesota first, then benchmark localities. Bars start at $0.

Every other payment area

64646 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$151.45$93.29
ArkansasArkansas$149.10$92.00
ArizonaArizona$165.07$100.67
Bakersfield, CACalifornia$174.36$101.51
Chico, CACalifornia$173.08$100.23
El Centro, CACalifornia$173.16$100.31
Fresno, CACalifornia$173.08$100.23
Hanford, CACalifornia$173.08$100.23

64646 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$149.10

$198.75

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
64646 office rate range by state
State / territoryOffice rate rangeLocalities
AK$198.751
AL$151.451
AR$149.101
AZ$165.071
CA$173.08–$211.5929
CO$173.651
CT$182.241
DC$192.331
DE$167.871
FL$174.21–$198.773
GA$163.11–$175.272
GU$176.681
HI$176.681
IA$152.561
ID$154.251
IL$171.06–$192.004
IN$155.131
KS$153.221
KY$158.381
LA$158.69–$166.892
MA$173.09–$189.522
MD$170.76–$192.333
ME$156.64–$163.572
MI$164.10–$178.002
MN$161.831
MO$156.75–$165.793
MS$152.881
MT$170.311
NC$158.161
ND$160.821
NE$153.021
NH$172.261
NJ$183.04–$190.422
NM$165.641
NV$167.761
NY$160.81–$205.905
OH$162.161
OK$156.551
OR$165.20–$177.782
PA$161.63–$178.412
PR$171.151
RI$172.881
SC$160.681
SD$159.701
TN$154.231
TX$160.61–$176.178
UT$162.981
VA$164.01–$192.332
VI$171.151
VT$161.471
WA$172.34–$192.032
WI$155.241
WV$164.741
WY$166.181

See 64646 in every payment locality

How the 64646 rate is calculated

Each of 64646’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 64646

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.76

1.76 RVUs× 1.000 GPCI

Practice expense2.86

2.86 RVUs× 1.000 GPCI

Malpractice0.48

0.48 RVUs× 1.000 GPCI

Adjusted RVUs

5.1000

Conversion factor

$33.4009

Medicare rate

$170.34

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Minnesota inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

7,189

Code
64646
Physician work
1.76
Practice expense
2.86
Malpractice
0.48

GPCI2026.csv

66

Locality
Minnesota
Physician work
1.000
Practice expense
1.029
Malpractice
0.296
Office calculation for 64646 in Minnesota
ComponentRVULocality factorAdjusted
Physician work1.76× 1.0001.7600
Practice expense2.86× 1.0292.9429
Malpractice0.48× 0.2960.1421
Total RVUs4.8450
Conversion factor× 33.4009

Office rate, Minnesota$161.83

Office: (1.76 × 1 + 2.86 × 1.029 + 0.48 × 0.296) × $33.4009 = $161.83

Facility: (1.76 × 1 + 0.87 × 1.029 + 0.48 × 0.296) × $33.4009 = $93.43

Open 64646 in the RVU calculator

Payment rules and modifiers for 64646

The CMS indicators that decide how 64646 is paid alongside other services.

CMS payment indicators · 64646

Muscle chemodenervation, trunk, one to five muscles

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

64646 without 51 · national office

$170.34

Muscle chemodenervation, trunk, one to five muscles

64646-51 · Second procedure: 50%

$85.17

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

How 64646 has changed in Minnesota

64646 · Office / nonfacility

$161.83

Effective 2026-10-01

The base rate is $12.88 higher than on 2025-10-01, moving from $148.95 to $161.83 (8.6%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $148.95changed to$161.83

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.80 changed to 1.76
    • Practice expense RVU 2.59 changed to 2.86
    • Malpractice RVU 0.50 changed to 0.48
    • Practice expense GPCI 1.025 changed to 1.029
    • Malpractice GPCI 0.300 changed to 0.296

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $152.84changed to$148.95

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 2.58 changed to 2.59
    • Malpractice RVU 0.49 changed to 0.50

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $150.34changed to$152.84

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $152.39changed to$150.34

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 2.49 changed to 2.58
    • Practice expense GPCI 1.019 changed to 1.025
    • Malpractice GPCI 0.326 changed to 0.300
  5. January 1, 2023

    RVU23A

    $154.48changed to$152.39

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 2.48 changed to 2.49
    • Malpractice RVU 0.43 changed to 0.49
    • Practice expense GPCI 1.013 changed to 1.019
    • Malpractice GPCI 0.353 changed to 0.326

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $152.58changed to$154.48

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 2.39 changed to 2.48

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $150.59changed to$152.58

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 2.20 changed to 2.39
    • Malpractice RVU 0.41 changed to 0.43
    • Practice expense GPCI 1.012 changed to 1.013
    • Malpractice GPCI 0.357 changed to 0.353

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $147.72changed to$150.59

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 2.12 changed to 2.20
    • Malpractice RVU 0.43 changed to 0.41
    • Practice expense GPCI 1.011 changed to 1.012
    • Malpractice GPCI 0.362 changed to 0.357

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $145.51changed to$147.72

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 2.06 changed to 2.12
    • Malpractice RVU 0.44 changed to 0.43

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $143.64changed to$145.51

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 2.02 changed to 2.06
    • Practice expense GPCI 1.016 changed to 1.011
    • Malpractice GPCI 0.341 changed to 0.362

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $144.96changed to$143.64

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 2.07 changed to 2.02
    • Malpractice RVU 0.43 changed to 0.44
    • Practice expense GPCI 1.020 changed to 1.016
    • Malpractice GPCI 0.319 changed to 0.341

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $148.53changed to$144.96

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 2.15 changed to 2.07
    • Malpractice RVU 0.44 changed to 0.43

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $147.79changed to$148.53

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $145.20changed to$147.79

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 2.12 changed to 2.15
    • Malpractice RVU 0.33 changed to 0.44
    • Practice expense GPCI 1.016 changed to 1.020
    • Malpractice GPCI 0.301 changed to 0.319

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    No ratechanged to$145.20

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$161.83$93.43RVU26D
2026-07-01$161.83$93.43RVU26C
2026-04-01$161.83$93.43RVU26B
2026-01-01$161.83$93.43RVU26A
2025-10-01$148.95$103.52RVU25D
2025-07-01$148.95$103.52RVU25C
2025-04-01$148.95$103.52RVU25B
2025-01-01$148.95$103.52RVU25A
2024-10-01$152.84$105.75RVU24D
2024-07-01$152.84$105.75RVU24C
2024-04-01$152.84$105.75RVU24B
2024-03-09$152.84$105.75RVU24AR
2024-01-01$150.34$104.03RVU24A
2023-10-01$152.39$106.47RVU23D
2023-07-01$152.39$106.47RVU23C
2023-04-01$152.39$106.47RVU23B
2023-01-01$152.39$106.47RVU23A
2022-10-01$154.48$108.56RVU22D
2022-07-01$154.48$108.56RVU22C
2022-04-01$154.48$108.56RVU22B
2022-01-01$154.48$108.56RVU22A
2021-10-01$152.58$109.11RVU21D
2021-07-01$152.58$109.11RVU21C
2021-04-01$152.58$109.11RVU21B
2021-01-01$152.58$109.11RVU21A
2020-10-01$150.59$110.78RVU20D
2020-07-01$150.59$110.78RVU20C
2020-04-01$150.59$110.78RVU20B
2020-01-01$150.59$110.78RVU20A
2019-10-01$147.72$110.92RVU19D
2019-07-01$147.72$110.92RVU19C
2019-04-01$147.72$110.92RVU19B
2019-01-01$147.72$110.92RVU19A
2018-10-01$145.51$111.30RVU18D
2018-07-01$145.51$111.30RVU18C
2018-04-01$145.51$111.30RVU18B
2018-01-01$145.51$111.30RVU18AR1
2017-10-01$143.64$111.19RVU17D
2017-07-01$143.64$111.19RVU17C
2017-04-01$143.64$111.19RVU17B
2017-01-01$143.64$111.19RVU17A
2016-10-01$144.96$111.36RVU16D
2016-07-01$144.96$111.36RVU16C
2016-04-01$144.96$111.36RVU16B
2016-01-01$144.96$111.36RVU16A
2015-10-01$148.53$112.61RVU15D
2015-07-01$148.53$112.61RVU15C
2015-04-01$147.79$112.05RVU15B
2015-01-01$147.79$112.05RVU15A
2014-10-01$145.20$110.99RVU14D
2014-07-01$145.20$110.99RVU14C
2014-04-01$145.20$110.99RVU14B
2014-01-01$145.20$110.99RVU14A
2013-10-01Not in this releaseNot in this releaseRVU13D
2013-07-01Not in this releaseNot in this releaseRVU13C
2013-04-01Not in this releaseNot in this releaseRVU13B
2013-01-01Not in this releaseNot in this releaseRVU13AR

Price 64646 for an earlier date of service

Where the Minnesota rate applies

Minnesota is a Medicare payment area, not a city. Our Census mapping connects it to 916 cities and communities in Minnesota. Some span more than one payment area; confirm with the service ZIP.

  • Ada
  • Adams
  • Adrian
  • Afton
  • Aitkin
  • Akeley
  • Albany
  • Albert Lea

Browse all communities in Minnesota

64646 billing questions

How is this code distinguished from the six-or-more trunk muscle code?

Count the distinct trunk muscles treated during the session. Report this code for one to five muscles and the six-or-more code when at least six are treated.

Do injection sites or toxin units determine the code?

No. The threshold is based on the number of trunk muscles treated, not the number of needle placements or units of medication.

Can modifier 50 be used for bilateral trunk injections?

No. CMS identifies bilateral adjustment as inappropriate for this code; do not use modifier 50 to represent treatment on both sides.

Is same-day evaluation or postoperative care separately included?

The code has a 0-day global period, with same-day preoperative and postoperative care included.

How are other procedures in the same session paid?

Under the standard multiple procedure reduction, the highest-valued procedure is paid in full and other procedures are paid at 50%.

Can an assistant, co-surgeon, or surgical team be reported?

Assistant-at-surgery payment is statutorily restricted. Co-surgeons and team surgery are not permitted for this code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 64646PPRRVU2026_Oct_nonQPP.csv, line 7,189 (RVU26D)
Geographic factors for MinnesotaGPCI2026.csv, line 66 (RVU26D)

Open CMS sourceHow we calculate rates

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