CPT code 78130: Red-cell survival, erythrocyte lifespan2026 Medicare rate & RVUs in Mississippi

Reports a nuclear medicine study that tracks labeled red blood cells over time to assess their survival in patients with suspected shortened erythrocyte lifespan.

CMS RVU26DEffective Oct 1, 2026One payment locality

In Mississippi, Medicare pays $111.74 for 78130 in the office.

$111.74Office (non-facility)
Not available in this settingHospital or facility
−12.0%vs the national office rate ($126.92)

Check a contract rate as a % of Medicare · 78130 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 78130 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Mississippi
  2. What 78130 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 78130 covers

For this study, the patient’s red blood cells are labeled and returned to circulation, then evaluated through follow-up sampling to estimate how long they survive. It is used in investigations of suspected hemolysis or other causes of shortened red-cell lifespan. Nuclear medicine personnel perform the technical work, and a qualified physician interprets the results. The service may be provided through a hospital or other diagnostic testing setting that can manage cell labeling and serial assessment.

Report 78130 when the documented service evaluates red-cell survival, not simply red-cell quantity or the location of cell sequestration. The record should support the labeling and administration of the cells, the survival assessment, and the physician’s interpretation and report. CMS recognizes a professional component for interpretation and a technical component for equipment and staff: report modifier 26 for the interpretation, modifier TC for the technical service, or neither modifier for the global service when one entity provides both components.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Mississippi compares for 78130

Across 109 of 109 payment localities, the office rate for 78130 runs from $111.00 in Arkansas to $174.36 in San Benito County, CA. Mississippi pays $111.74. The RVUs are the same everywhere; the geographic indexes change the dollars.

78130 in Mississippi vs other payment areas
  1. Mississippi · this page$111.74
  2. Los Angeles, CA · California$146.14+$34.40
  3. Washington, DC area · District of Columbia$146.92+$35.18
  4. Miami, FL · Florida$134.80+$23.06
  5. Chicago, IL · Illinois$130.61+$18.87
  6. Manhattan, NY · New York$146.55+$34.81
  7. Alaska · Alaska$142.54+$30.80

Other areas in Mississippi first, then benchmark localities. Bars start at $0.

Every other payment area

78130 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$112.80—
ArkansasArkansas$111.00—
ArizonaArizona$123.34—
Bakersfield, CACalifornia$136.45—
Chico, CACalifornia$136.24—
El Centro, CACalifornia$136.25—
Fresno, CACalifornia$136.24—
Hanford, CACalifornia$136.24—

78130 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$111.00

$155.30

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
78130 office rate range by state
State / territoryOffice rate rangeLocalities
AK$142.541
AL$112.801
AR$111.001
AZ$123.341
CA$136.24–$174.3629
CO$133.361
CT$135.881
DC$146.921
DE$125.531
FL$123.48–$134.803
GA$116.05–$129.132
GU$140.311
HI$140.311
IA$116.601
ID$117.301
IL$119.12–$131.704
IN$118.071
KS$115.701
KY$115.081
LA$114.76–$121.052
MA$132.32–$147.822
MD$128.19–$146.923
ME$117.65–$125.122
MI$118.10–$124.862
MN$128.321
MO$112.39–$121.893
MS$111.741
MT$126.921
NC$119.051
ND$125.531
NE$117.391
NH$130.931
NJ$137.59–$145.102
NM$118.691
NV$126.641
NY$120.99–$150.015
OH$117.821
OK$115.181
OR$125.81–$138.282
PA$118.19–$132.032
PR$128.041
RI$130.511
SC$118.601
SD$125.371
TN$116.301
TX$117.32–$132.788
UT$120.391
VA$124.45–$146.922
VI$128.041
VT$124.721
WA$132.18–$151.292
WI$120.901
WV$114.191
WY$126.321

See 78130 in every payment locality

How the 78130 rate is calculated

Each of 78130’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 78130

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.59

0.59 RVUs× 1.000 GPCI

Practice expense3.14

3.14 RVUs× 1.000 GPCI

Malpractice0.07

0.07 RVUs× 1.000 GPCI

Adjusted RVUs

3.8000

Conversion factor

$33.4009

Medicare rate

$126.92

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Mississippi inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

9,239

Code
78130
Physician work
0.59
Practice expense
3.14
Malpractice
0.07

GPCI2026.csv

67

Locality
Mississippi
Physician work
1.000
Practice expense
0.861
Malpractice
0.739
Office calculation for 78130 in Mississippi
ComponentRVULocality factorAdjusted
Physician work0.59× 1.0000.5900
Practice expense3.14× 0.8612.7035
Malpractice0.07× 0.7390.0517
Total RVUs3.3453
Conversion factor× 33.4009

Office rate, Mississippi$111.74

Office: (0.59 × 1 + 3.14 × 0.861 + 0.07 × 0.739) × $33.4009 = $111.74

Open 78130 in the RVU calculator

Payment rules and modifiers for 78130

The CMS indicators that decide how 78130 is paid alongside other services.

CMS payment indicators · 78130

Red-cell survival, erythrocyte lifespan

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

78130 without 26 · national office

$126.92

Red-cell survival, erythrocyte lifespan

78130-26 · Professional component

$23.71

Pays only the interpretation and report.

When to use modifier 26

How 78130 has changed in Mississippi

78130 · Office / nonfacility

$111.74

Effective 2026-10-01

The base rate is $6.19 higher than on 2025-10-01, moving from $105.55 to $111.74 (5.9%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $105.55changed to$111.74

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.61 changed to 0.59
    • Practice expense RVU 3.06 changed to 3.14
    • Malpractice RVU 0.06 changed to 0.07
    • Practice expense GPCI 0.852 changed to 0.861
    • Malpractice GPCI 0.768 changed to 0.739

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $108.31changed to$105.55

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 3.04 changed to 3.06
    • Malpractice RVU 0.07 changed to 0.06

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $106.54changed to$108.31

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $108.77changed to$106.54

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 3.01 changed to 3.04
    • Practice expense GPCI 0.847 changed to 0.852
    • Malpractice GPCI 0.720 changed to 0.768
  5. January 1, 2023

    RVU23A

    $111.08changed to$108.77

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 3.04 changed to 3.01
    • Malpractice RVU 0.06 changed to 0.07
    • Practice expense GPCI 0.842 changed to 0.847
    • Malpractice GPCI 0.671 changed to 0.720

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $111.71changed to$111.08

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 3.03 changed to 3.04

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $113.35changed to$111.71

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 2.92 changed to 3.03
    • Practice expense GPCI 0.856 changed to 0.842
    • Malpractice GPCI 0.521 changed to 0.671

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $113.58changed to$113.35

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 2.90 changed to 2.92
    • Malpractice RVU 0.05 changed to 0.06
    • Practice expense GPCI 0.870 changed to 0.856
    • Malpractice GPCI 0.370 changed to 0.521

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $126.61changed to$113.58

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 3.32 changed to 2.90

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $154.26changed to$126.61

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 4.22 changed to 3.32
    • Malpractice RVU 0.06 changed to 0.05
    • Practice expense GPCI 0.867 changed to 0.870
    • Malpractice GPCI 0.492 changed to 0.370

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $153.70changed to$154.26

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense GPCI 0.864 changed to 0.867
    • Malpractice GPCI 0.613 changed to 0.492

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $144.10changed to$153.70

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 3.90 changed to 4.22
    • Malpractice RVU 0.05 changed to 0.06

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $143.39changed to$144.10

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $152.73changed to$143.39

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 4.16 changed to 3.90
    • Malpractice RVU 0.08 changed to 0.05
    • Practice expense GPCI 0.865 changed to 0.864
    • Malpractice GPCI 0.687 changed to 0.613

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $145.40changed to$152.73

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense GPCI 0.866 changed to 0.865
    • Malpractice GPCI 0.761 changed to 0.687

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $145.40

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$111.74Not available in this settingRVU26D
2026-07-01$111.74Not available in this settingRVU26C
2026-04-01$111.74Not available in this settingRVU26B
2026-01-01$111.74Not available in this settingRVU26A
2025-10-01$105.55Not available in this settingRVU25D
2025-07-01$105.55Not available in this settingRVU25C
2025-04-01$105.55Not available in this settingRVU25B
2025-01-01$105.55Not available in this settingRVU25A
2024-10-01$108.31Not available in this settingRVU24D
2024-07-01$108.31Not available in this settingRVU24C
2024-04-01$108.31Not available in this settingRVU24B
2024-03-09$108.31Not available in this settingRVU24AR
2024-01-01$106.54Not available in this settingRVU24A
2023-10-01$108.77Not available in this settingRVU23D
2023-07-01$108.77Not available in this settingRVU23C
2023-04-01$108.77Not available in this settingRVU23B
2023-01-01$108.77Not available in this settingRVU23A
2022-10-01$111.08Not available in this settingRVU22D
2022-07-01$111.08Not available in this settingRVU22C
2022-04-01$111.08Not available in this settingRVU22B
2022-01-01$111.08Not available in this settingRVU22A
2021-10-01$111.71Not available in this settingRVU21D
2021-07-01$111.71Not available in this settingRVU21C
2021-04-01$111.71Not available in this settingRVU21B
2021-01-01$111.71Not available in this settingRVU21A
2020-10-01$113.35Not available in this settingRVU20D
2020-07-01$113.35Not available in this settingRVU20C
2020-04-01$113.35Not available in this settingRVU20B
2020-01-01$113.35Not available in this settingRVU20A
2019-10-01$113.58Not available in this settingRVU19D
2019-07-01$113.58Not available in this settingRVU19C
2019-04-01$113.58Not available in this settingRVU19B
2019-01-01$113.58Not available in this settingRVU19A
2018-10-01$126.61Not available in this settingRVU18D
2018-07-01$126.61Not available in this settingRVU18C
2018-04-01$126.61Not available in this settingRVU18B
2018-01-01$126.61Not available in this settingRVU18AR1
2017-10-01$154.26Not available in this settingRVU17D
2017-07-01$154.26Not available in this settingRVU17C
2017-04-01$154.26Not available in this settingRVU17B
2017-01-01$154.26Not available in this settingRVU17A
2016-10-01$153.70Not available in this settingRVU16D
2016-07-01$153.70Not available in this settingRVU16C
2016-04-01$153.70Not available in this settingRVU16B
2016-01-01$153.70Not available in this settingRVU16A
2015-10-01$144.10Not available in this settingRVU15D
2015-07-01$144.10Not available in this settingRVU15C
2015-04-01$143.39Not available in this settingRVU15B
2015-01-01$143.39Not available in this settingRVU15A
2014-10-01$152.73Not available in this settingRVU14D
2014-07-01$152.73Not available in this settingRVU14C
2014-04-01$152.73Not available in this settingRVU14B
2014-01-01$152.73Not available in this settingRVU14A
2013-10-01$145.40Not available in this settingRVU13D
2013-07-01$145.40Not available in this settingRVU13C
2013-04-01$145.40Not available in this settingRVU13B
2013-01-01$145.40Not available in this settingRVU13AR

Price 78130 for an earlier date of service

Where the Mississippi rate applies

Mississippi is a Medicare payment area, not a city. Our Census mapping connects it to 427 cities and communities in Mississippi. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Aberdeen
  • Ackerman
  • Agricola
  • Alcorn State University
  • Algoma
  • Alligator
  • Amory

Browse all communities in Mississippi

78130 billing questions

How is 78130 different from a red-cell mass study?

78130 evaluates how long circulating red cells survive. Red-cell mass testing measures the amount of red-cell volume rather than cell lifespan.

When should modifier 26 or TC be used?

Use modifier 26 for the physician’s interpretation and report, and TC for the technical service. Report the global service without either modifier when both components are billed together.

Does 78130 include a red-cell sequestration study?

The survival assessment and sequestration assessment address different findings. Report 78130 for the survival work performed; the documentation should identify any separately performed sequestration study.

What documentation supports reporting 78130?

Document the red-cell labeling and administration, the survival assessment, and the interpretation. The record should establish that the test evaluates red-cell lifespan rather than mass alone.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 78130PPRRVU2026_Oct_nonQPP.csv, line 9,239 (RVU26D)
Geographic factors for MississippiGPCI2026.csv, line 67 (RVU26D)

Open CMS sourceHow we calculate rates

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