CPT code 78452: Nuclear stress test, SPECT, multiple perfusion studies2026 Medicare rate & RVUs in South Dakota

Myocardial perfusion SPECT with multiple distinct studies, typically rest and stress imaging, is reported for the complete multiple-study examination.

CMS RVU26DEffective Oct 1, 2026One payment locality1.2M Medicare services in 2024

In South Dakota, Medicare pays $424.98 for 78452 in the office.

$424.98Office (non-facility)
Not available in this settingHospital or facility
−0.7%vs the national office rate ($427.87)

Check a contract rate as a % of Medicare · 78452 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 78452 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in South Dakota
  2. What 78452 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 78452 covers

Myocardial perfusion SPECT uses a radiotracer, such as technetium-99m sestamibi or tetrofosmin, and a gamma camera to assess blood flow to the heart muscle. Separate studies are commonly acquired at rest and after exercise or pharmacologic stress; redistribution or reinjection imaging may also be performed. Comparing the studies helps distinguish reversible perfusion defects from fixed defects. Attenuation correction, wall motion, ejection fraction, and additional quantification are included when performed. Nuclear cardiology teams perform the scan in offices, imaging centers, and hospital departments; a cardiologist or nuclear medicine physician interprets it.

Report one unit for the complete multiple-study SPECT examination, even when its phases occur on different days. Document the distinct study phases, tracer, stress method, and imaging findings. A separately performed and documented cardiovascular stress test may be reported with 93015 or the appropriate 93016–93018 components; tracer and stress-agent billing depends on the setting. Use modifier 26 for interpretation only, TC for the equipment and staff portion, or no component modifier for the global service. CMS applies the cardiovascular diagnostic multiple procedure reduction to the technical component when applicable.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Dakota compares for 78452

Across 109 of 109 payment localities, the office rate for 78452 runs from $373.48 in Arkansas to $595.53 in San Benito County, CA. South Dakota pays $424.98. The RVUs are the same everywhere; the geographic indexes change the dollars.

78452 in South Dakota vs other payment areas
  1. South Dakota · this page$424.98
  2. Los Angeles, CA · California$496.42+$71.44
  3. Washington, DC area · District of Columbia$497.20+$72.22
  4. Miami, FL · Florida$449.71+$24.73
  5. Chicago, IL · Illinois$435.71+$10.73
  6. Manhattan, NY · New York$493.85+$68.87
  7. Alaska · Alaska$476.40+$51.42

Other areas in South Dakota first, then benchmark localities. Bars start at $0.

Every other payment area

78452 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$379.64—
ArkansasArkansas$373.48—
ArizonaArizona$415.75—
Bakersfield, CACalifornia$462.76—
Chico, CACalifornia$462.34—
El Centro, CACalifornia$462.36—
Fresno, CACalifornia$462.34—
Hanford, CACalifornia$462.34—

78452 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$373.48

$528.94

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
78452 office rate range by state
State / territoryOffice rate rangeLocalities
AK$476.401
AL$379.641
AR$373.481
AZ$415.751
CA$462.34–$595.5329
CO$451.281
CT$458.381
DC$497.201
DE$423.241
FL$413.74–$449.713
GA$388.66–$434.832
GU$476.831
HI$476.831
IA$393.731
ID$395.921
IL$398.05–$441.604
IN$398.571
KS$390.121
KY$386.341
LA$385.05–$406.582
MA$447.48–$501.482
MD$432.49–$497.203
ME$396.56–$422.932
MI$396.17–$417.872
MN$435.561
MO$376.59–$410.083
MS$375.201
MT$427.861
NC$401.461
ND$425.291
NE$396.621
NH$442.521
NJ$464.51–$490.812
NM$397.971
NV$427.511
NY$408.04–$505.045
OH$395.651
OK$387.231
OR$425.09–$468.752
PA$397.23–$444.852
PR$431.881
RI$440.631
SC$399.041
SD$424.981
TN$392.121
TX$394.19–$448.988
UT$405.181
VA$420.29–$497.202
VI$431.881
VT$422.011
WA$447.16–$513.872
WI$409.291
WV$381.171
WY$426.741

See 78452 in every payment locality

How the 78452 rate is calculated

Each of 78452’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 78452

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.58

1.58 RVUs× 1.000 GPCI

Practice expense11.10

11.10 RVUs× 1.000 GPCI

Malpractice0.13

0.13 RVUs× 1.000 GPCI

Adjusted RVUs

12.8100

Conversion factor

$33.4009

Medicare rate

$427.87

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact South Dakota inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

9,368

Code
78452
Physician work
1.58
Practice expense
11.10
Malpractice
0.13

GPCI2026.csv

94

Locality
South Dakota
Physician work
1.000
Practice expense
1.000
Malpractice
0.336
Office calculation for 78452 in South Dakota
ComponentRVULocality factorAdjusted
Physician work1.58× 1.0001.5800
Practice expense11.10× 1.00011.1000
Malpractice0.13× 0.3360.0437
Total RVUs12.7237
Conversion factor× 33.4009

Office rate, South Dakota$424.98

Office: (1.58 × 1 + 11.1 × 1 + 0.13 × 0.336) × $33.4009 = $424.98

Open 78452 in the RVU calculator

Payment rules and modifiers for 78452

The CMS indicators that decide how 78452 is paid alongside other services.

CMS payment indicators · 78452

Nuclear stress test, SPECT, multiple perfusion studies

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures6Diagnostic cardiovascular reduction applies to the technical component.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

78452 without 26 · national office

$427.87

Nuclear stress test, SPECT, multiple perfusion studies

78452-26 · Professional component

$74.48

Pays only the interpretation and report.

When to use modifier 26

How 78452 has changed in South Dakota

78452 · Office / nonfacility

$424.98

Effective 2026-10-01

The base rate is $18.52 higher than on 2025-10-01, moving from $406.46 to $424.98 (4.6%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $406.46changed to$424.98

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.62 changed to 1.58
    • Practice expense RVU 10.90 changed to 11.10
    • Malpractice RVU 0.12 changed to 0.13
    • Malpractice GPCI 0.382 changed to 0.336

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $429.52changed to$406.46

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 11.23 changed to 10.90
    • Malpractice RVU 0.14 changed to 0.12

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $422.51changed to$429.52

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $441.46changed to$422.51

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 11.36 changed to 11.23
    • Malpractice RVU 0.13 changed to 0.14
    • Malpractice GPCI 0.364 changed to 0.382
  5. January 1, 2023

    RVU23A

    $461.03changed to$441.46

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 11.65 changed to 11.36
    • Malpractice RVU 0.15 changed to 0.13
    • Malpractice GPCI 0.347 changed to 0.364

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $483.90changed to$461.03

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 12.21 changed to 11.65
    • Malpractice RVU 0.11 changed to 0.15

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $481.49changed to$483.90

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 11.67 changed to 12.21
    • Malpractice RVU 0.14 changed to 0.11
    • Malpractice GPCI 0.368 changed to 0.347

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $487.49changed to$481.49

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 11.86 changed to 11.67
    • Malpractice RVU 0.12 changed to 0.14
    • Malpractice GPCI 0.389 changed to 0.368

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $497.53changed to$487.49

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 12.15 changed to 11.86
    • Malpractice RVU 0.13 changed to 0.12

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $491.94changed to$497.53

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 12.04 changed to 12.15
    • Malpractice RVU 0.12 changed to 0.13
    • Malpractice GPCI 0.395 changed to 0.389

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $490.23changed to$491.94

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 12.02 changed to 12.04
    • Malpractice RVU 0.13 changed to 0.12
    • Malpractice GPCI 0.400 changed to 0.395

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $490.28changed to$490.23

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 11.98 changed to 12.02
    • Malpractice RVU 0.11 changed to 0.13

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $487.84changed to$490.28

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $484.59changed to$487.84

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 11.87 changed to 11.98
    • Malpractice RVU 0.09 changed to 0.11
    • Malpractice GPCI 0.416 changed to 0.400

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $500.44changed to$484.59

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 13.05 changed to 11.87
    • Malpractice GPCI 0.432 changed to 0.416

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $500.44

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$424.98Not available in this settingRVU26D
2026-07-01$424.98Not available in this settingRVU26C
2026-04-01$424.98Not available in this settingRVU26B
2026-01-01$424.98Not available in this settingRVU26A
2025-10-01$406.46Not available in this settingRVU25D
2025-07-01$406.46Not available in this settingRVU25C
2025-04-01$406.46Not available in this settingRVU25B
2025-01-01$406.46Not available in this settingRVU25A
2024-10-01$429.52Not available in this settingRVU24D
2024-07-01$429.52Not available in this settingRVU24C
2024-04-01$429.52Not available in this settingRVU24B
2024-03-09$429.52Not available in this settingRVU24AR
2024-01-01$422.51Not available in this settingRVU24A
2023-10-01$441.46Not available in this settingRVU23D
2023-07-01$441.46Not available in this settingRVU23C
2023-04-01$441.46Not available in this settingRVU23B
2023-01-01$441.46Not available in this settingRVU23A
2022-10-01$461.03Not available in this settingRVU22D
2022-07-01$461.03Not available in this settingRVU22C
2022-04-01$461.03Not available in this settingRVU22B
2022-01-01$461.03Not available in this settingRVU22A
2021-10-01$483.90Not available in this settingRVU21D
2021-07-01$483.90Not available in this settingRVU21C
2021-04-01$483.90Not available in this settingRVU21B
2021-01-01$483.90Not available in this settingRVU21A
2020-10-01$481.49Not available in this settingRVU20D
2020-07-01$481.49Not available in this settingRVU20C
2020-04-01$481.49Not available in this settingRVU20B
2020-01-01$481.49Not available in this settingRVU20A
2019-10-01$487.49Not available in this settingRVU19D
2019-07-01$487.49Not available in this settingRVU19C
2019-04-01$487.49Not available in this settingRVU19B
2019-01-01$487.49Not available in this settingRVU19A
2018-10-01$497.53Not available in this settingRVU18D
2018-07-01$497.53Not available in this settingRVU18C
2018-04-01$497.53Not available in this settingRVU18B
2018-01-01$497.53Not available in this settingRVU18AR1
2017-10-01$491.94Not available in this settingRVU17D
2017-07-01$491.94Not available in this settingRVU17C
2017-04-01$491.94Not available in this settingRVU17B
2017-01-01$491.94Not available in this settingRVU17A
2016-10-01$490.23Not available in this settingRVU16D
2016-07-01$490.23Not available in this settingRVU16C
2016-04-01$490.23Not available in this settingRVU16B
2016-01-01$490.23Not available in this settingRVU16A
2015-10-01$490.28Not available in this settingRVU15D
2015-07-01$490.28Not available in this settingRVU15C
2015-04-01$487.84Not available in this settingRVU15B
2015-01-01$487.84Not available in this settingRVU15A
2014-10-01$484.59Not available in this settingRVU14D
2014-07-01$484.59Not available in this settingRVU14C
2014-04-01$484.59Not available in this settingRVU14B
2014-01-01$484.59Not available in this settingRVU14A
2013-10-01$500.44Not available in this settingRVU13D
2013-07-01$500.44Not available in this settingRVU13C
2013-04-01$500.44Not available in this settingRVU13B
2013-01-01$500.44Not available in this settingRVU13AR

Price 78452 for an earlier date of service

Where the South Dakota rate applies

South Dakota is a Medicare payment area, not a city. Our Census mapping connects it to 485 cities and communities in South Dakota. Some span more than one payment area; confirm with the service ZIP.

  • Aberdeen
  • Agar
  • Agency Village
  • Akaska
  • Albee
  • Alcester
  • Alexandria
  • Allen

Browse all communities in South Dakota

78452 billing questions

When should 78451 be used instead of 78452?

Use 78451 for one SPECT perfusion study, such as a stress-only protocol in which rest imaging is omitted. Use 78452 when multiple distinct perfusion studies are performed, such as rest and stress.

Is the treadmill or pharmacologic stress test included?

The separately performed and documented cardiovascular stress test may be reported with 93015, or with the appropriate components 93016, 93017, and 93018 when the work is split. Separate billing for the radiotracer or pharmacologic stress agent depends on the setting.

Can gated wall motion or ejection fraction be billed separately?

Wall motion, ejection fraction, attenuation correction, and additional quantification are included in 78452 when performed. Do not add a gated blood pool code solely to report function data obtained from the perfusion study.

How is a two-day protocol reported?

Report one unit of 78452 for the complete multiple-study examination when its phases occur on two days. Document the phases performed on each day.

Which modifiers apply in a hospital setting?

A physician billing only the interpretation uses 78452-26; the hospital bills its facility services separately. A practice furnishing both the technical service and interpretation bills the global code without a component modifier.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 78452PPRRVU2026_Oct_nonQPP.csv, line 9,368 (RVU26D)
Geographic factors for South DakotaGPCI2026.csv, line 94 (RVU26D)

Open CMS sourceHow we calculate rates

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