CPT code 80081: Obstetric panel, includes HIV testing2026 Medicare lab fee · Clinical Laboratory Fee Schedule
This prenatal blood-test panel includes blood counts, blood typing, and infection screening, including HIV testing, when the complete panel is performed.
Medicare pays $74.86 for 80081 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$74.86
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 80081 covers
This prenatal blood panel includes a complete blood count with a specified automated or manual white-cell differential combination, hepatitis B surface antigen, HIV-1 antigen and HIV-1/HIV-2 antibody testing, rubella antibody testing, qualitative non-treponemal syphilis testing, a red-cell antibody screen, and ABO and Rh blood typing. It is typically performed by a clinical laboratory for an obstetric clinician as part of prenatal evaluation.
Report one panel when its required tests are performed as a set; the code represents the panel, not a count of individual tests. Medicare pays this test only through the Clinical Laboratory Fee Schedule. The 2026 national CLFS amount is $74.86, unchanged from 2020 through 2026. The same amount applies across states and localities, without geographic adjustment or an office-versus-facility difference.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 80081
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 80081. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 80081 with status X (excluded by statute), so the test itself is paid only from the CLFS.
80081 on the lab fee schedule since 2020
80081 · CLFS 2026 Q4 (current)
$74.86
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
80081 compared with similar tests
- 80055Obstetric panelWithout HIV testing$47.81
- Both are obstetric panels, but 80081 includes HIV testing; 80055 is the related panel without that component.
- 87389HIV screenHIV-1 antigen plus HIV-1/2 antibodies$24.08
- Code 87389 is a standalone HIV antigen and antibody test. Code 80081 is the broader obstetric panel that includes HIV testing.
- 80074Hepatitis panelFour viral markers$47.63
- Code 80074 is an acute hepatitis panel; 80081 is an obstetric panel that includes hepatitis B surface antigen testing and other prenatal screening tests.
80081 billing questions
How does this differ from 80055?
Code 80081 includes HIV testing in the obstetric panel. Code 80055 is the related obstetric panel without HIV testing.
What tests are included?
The panel includes a CBC with a specified differential, hepatitis B surface antigen, HIV testing, rubella antibody, non-treponemal syphilis testing, a red-cell antibody screen, and ABO and Rh blood typing.
Can the included tests also be billed separately?
Do not separately report the same tests as individual services when reporting them as part of this panel.
How does Medicare pay for 80081?
Medicare pays the test through the CLFS at one national amount, with no geographic or office-versus-facility adjustment.
When would a standalone test be reported instead?
Use an applicable individual test, such as 87389 for HIV antigen and antibody testing, when that test is performed without the complete obstetric panel.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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