CPT code 80150: Amikacin level, therapeutic drug monitoring2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Measures amikacin concentration in a patient specimen to monitor antibiotic exposure during treatment and guide dosing or toxicity assessment.
Medicare pays $15.08 for 80150 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$15.08
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 80150 covers
This assay measures amikacin, an aminoglycoside antibiotic, in serum. Clinicians may order it during treatment of serious bacterial infections to assess drug exposure and support dosing decisions, particularly when monitoring for toxicity or managing factors that can affect drug clearance. Peak or trough sampling may be used when clinically indicated; collection timing is interpreted in relation to the dosing schedule. Clinical laboratories perform and report the concentration for the ordering clinician.
Report 80150 for the amikacin assay performed; the code identifies the drug measured, not a particular sampling time. Medicare pays it through the CLFS at one national rate, with no locality or office-versus-facility adjustment. The 2026 national CLFS amount is $15.08, unchanged from 2020 through 2026. The test is paid only under the CLFS, not the physician fee schedule.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 80150
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 80150. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 80150 with status X (excluded by statute), so the test itself is paid only from the CLFS.
80150 on the lab fee schedule since 2020
80150 · CLFS 2026 Q4 (current)
$15.08
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
80150 compared with similar tests
- 80170Gentamicin assayTherapeutic drug monitoring$16.38
- Choose 80150 for amikacin concentration and 80170 for gentamicin concentration. Both are aminoglycosides, but the assay code follows the specific drug tested.
- 80151Amiodarone assay$18.64
- 80151 measures amiodarone, an antiarrhythmic drug; 80150 measures the antibiotic amikacin.
- 80156Carbamazepine levelTotal concentration$14.57
- 80156 measures total carbamazepine, an antiseizure medication. Use 80150 when the measured analyte is amikacin.
80150 billing questions
When should 80150 be selected instead of the gentamicin assay?
Use 80150 when the measured drug is amikacin. The gentamicin assay, 80170, applies when monitoring gentamicin.
Does 80150 distinguish peak from trough testing?
No. The code identifies amikacin measurement; document the collection timing and its relationship to dosing when relevant to interpreting the result.
What specimen is typically tested?
Serum is typically used for amikacin therapeutic drug monitoring.
Is 80150 paid under the physician fee schedule?
No. Medicare pays this test through the CLFS, using the same national amount across localities and office and facility settings.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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