CPT code 80151: Amiodarone assay2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Laboratory measurement of amiodarone, reported when testing determines the amount of this antiarrhythmic medication in a patient sample.
Medicare pays $18.64 for 80151 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$18.64
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2021
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 7 sections
What 80151 covers
Code 80151 identifies laboratory measurement of amiodarone, an antiarrhythmic medication. The assay reports the amount of this specific drug in a patient sample; it is not a broad drug screen or a panel of medication levels. Clinical laboratories perform the measurement, and the result is used by the treating clinician in assessing a patient receiving amiodarone.
Report 80151 for an amiodarone assay rather than a code naming another drug; the code represents the analyte measurement, not a prescribed dose. Medicare pays this test under the CLFS at one national amount across states and localities, with no geographic or office-versus-facility adjustment. The 2026 national amount is $18.64 and has remained the same in each year from 2021 through 2026. The test is excluded from the physician fee schedule and is paid only through the CLFS.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 80151
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 80151. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 80151 with status X (excluded by statute), so the test itself is paid only from the CLFS.
80151 on the lab fee schedule since 2021
80151 · CLFS 2026 Q4 (current)
$18.64
Unchanged since Jan 1, 2021
24 quarterly CLFS releases on file, first CLFS 2021 Q1. A code missing from a quarter wasn’t on that release.
80151 compared with similar tests
- 80162Digoxin assayTotal concentration$13.28
- Use 80162 for total digoxin measurement. Use 80151 when the assay measures amiodarone.
- 80150Amikacin levelTherapeutic drug monitoring$15.08
- Use 80150 for amikacin measurement; 80151 is specific to amiodarone.
- 80156Carbamazepine levelTotal concentration$14.57
- Use 80156 for total carbamazepine measurement. It does not identify an amiodarone assay.
80151 billing questions
When should this code be selected instead of another drug assay code?
Select it when the laboratory measures amiodarone. Use a different drug assay code when the ordered analyte is another medication, such as digoxin or carbamazepine.
Does this code include a panel of antiarrhythmic drug levels?
No. It identifies measurement of amiodarone, not a panel or measurement of other drugs.
Can a physician interpretation be billed separately under this code?
This test is paid only through the CLFS and is excluded from the physician fee schedule; the code does not provide a separate physician-interpretation payment.
How does Medicare pay for this assay?
Medicare pays one national CLFS amount across localities, without a geographic or office-versus-facility adjustment.
Is this code reported per dose of amiodarone?
No. The code identifies the laboratory measurement, not the prescribed dose.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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