CPT code 82607: Vitamin B12, level assay2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Measures vitamin B12 in a patient specimen, commonly to evaluate suspected deficiency associated with anemia, neurologic symptoms, or malabsorption.
Medicare pays $15.08 for 82607 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$15.08
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 82607 covers
This laboratory assay measures cyanocobalamin (vitamin B12), typically in serum or plasma. Clinicians may order it when evaluating macrocytic anemia, peripheral neuropathy or other neurologic symptoms, suspected malabsorption, or a possible nutritional deficiency. It may also be used to assess B12 status during treatment. Primary care clinicians, hematologists, neurologists, and gastroenterologists commonly order the test, which is performed by a clinical laboratory.
Report 82607 for the B12 level assay; it is distinct from B12-binding-capacity testing or a folate assay. Medicare pays the test through the CLFS, with one national amount per code across states and localities and no office-versus-facility payment difference. The 2026 national CLFS amount is $15.08, unchanged from 2020 through 2026. The test is paid only through the CLFS.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 82607
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 82607. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 82607 with status X (excluded by statute), so the test itself is paid only from the CLFS.
82607 on the lab fee schedule since 2020
82607 · CLFS 2026 Q4 (current)
$15.08
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
82607 compared with similar tests
- 82608B-12 bindingUnoccupied binding sites$14.32
- 82607 measures the vitamin B12 level; 82608 measures B12-binding capacity, a distinct test.
- 82746Folate testSerum specimen$14.70
- 82746 measures folate, not vitamin B12. The two assays may be ordered together but are separately reported.
- 83921Organic acidSingle analyte, quantitative$21.21
- 83921 measures methylmalonic acid, which can help assess functional B12 deficiency; it does not measure the B12 level itself.
82607 billing questions
When should 82607 be reported instead of 82608?
Report 82607 for measuring the patient's vitamin B12 level. Code 82608 describes B12-binding-capacity testing, a different laboratory measurement.
Is 82607 the same test as a folate assay?
No. 82607 measures vitamin B12; 82746 measures folate. Both may be ordered in an anemia evaluation, but they represent separate assays.
What should the medical record support?
Document the clinical reason for measuring B12, such as evaluation of anemia, neurologic symptoms, suspected malabsorption, or nutritional deficiency.
How does Medicare pay 82607?
Medicare pays one national CLFS amount per code across states and localities, with no office-versus-facility difference.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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