CPT code 86147: Cardiolipin antibody, each immunoglobulin class2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Measures cardiolipin antibodies by immunoglobulin class, commonly reported during evaluation of antiphospholipid syndrome in patients with thrombosis or pregnancy morbidity.
Medicare pays $25.45 for 86147 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$25.45
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 86147 covers
This laboratory test measures antibodies directed against cardiolipin, a phospholipid. It is used in evaluating suspected antiphospholipid syndrome, particularly in patients with thrombosis or pregnancy morbidity. Hematology, rheumatology, and obstetric clinicians may request it as part of an antiphospholipid antibody evaluation. The result identifies reactivity to cardiolipin for an immunoglobulin class and is distinct from testing for antibodies to beta-2 glycoprotein or other antiphospholipid targets.
Report the code for each immunoglobulin class measured; the code distinguishes classes rather than antibody concentration levels. Cardiolipin antibody testing may be performed with other tests in an antiphospholipid evaluation, including beta-2 glycoprotein antibody and lupus anticoagulant testing when ordered. Medicare pays 86147 only through the CLFS. The 2026 national CLFS amount is $25.45, unchanged since 2020, and applies across localities and office and facility settings.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 86147
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 86147. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 86147 with status X (excluded by statute), so the test itself is paid only from the CLFS.
86147 on the lab fee schedule since 2020
86147 · CLFS 2026 Q4 (current)
$25.45
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
86147 compared with similar tests
- 86146Beta-2 glycoproteinEach antibody class$25.45
- Use 86147 for cardiolipin antibodies by immunoglobulin class; use 86146 for beta-2 glycoprotein antibodies. These measure antibodies to different targets.
- 86148Anti-phospholipid antibodyPhosphatidylserine antibody$16.07
- Code 86148 represents a separate antiphospholipid antibody assay. Code 86147 is specific to cardiolipin antibodies and is reported by Ig class.
- 85613Viper venom testDiluted clotting assay$9.58
- Code 85613 is a coagulation assay used in lupus anticoagulant evaluation, not a cardiolipin antibody measurement. It may be performed as a separate part of the same evaluation.
86147 billing questions
How is this code selected when more than one Ig class is tested?
The code represents cardiolipin antibody testing for each immunoglobulin class. Report the class or classes actually tested.
How does this differ from beta-2 glycoprotein antibody testing?
Code 86147 measures antibodies directed against cardiolipin; 86146 measures antibodies directed against beta-2 glycoprotein. Both may be included in an antiphospholipid antibody evaluation.
Is this test paid under the physician fee schedule?
No. Medicare pays 86147 through the CLFS, with one national amount applying across localities and settings.
Can lupus anticoagulant testing be reported with this test?
Yes, when separately performed and supported by the clinical evaluation. Lupus anticoagulant testing assesses a different part of the antiphospholipid antibody workup.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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