CPT code 86148: Anti-phospholipid antibody, phosphatidylserine antibody2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Measures anti-phosphatidylserine antibodies and may be reported during evaluation of suspected antiphospholipid antibody-related thrombosis or pregnancy morbidity.
Medicare pays $16.07 for 86148 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$16.07
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 86148 covers
Clinical laboratories measure antibodies directed against phosphatidylserine, a phospholipid. Clinicians may order the test when evaluating suspected antiphospholipid antibody-associated conditions, including unexplained thrombosis or pregnancy morbidity. It measures a specific antibody target and is distinct from cardiolipin and beta-2 glycoprotein antibody tests.
Report 86148 for the anti-phosphatidylserine antibody measurement itself, rather than as a substitute for other antiphospholipid antibody tests. Medicare pays this laboratory service through the CLFS, with one national amount that applies across localities and has no office-versus-facility difference. The 2026 national CLFS amount is $16.07, unchanged since 2020. Medicare pays the code through the CLFS only, not the physician fee schedule.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 86148
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 86148. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 86148 with status X (excluded by statute), so the test itself is paid only from the CLFS.
86148 on the lab fee schedule since 2020
86148 · CLFS 2026 Q4 (current)
$16.07
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
86148 compared with similar tests
- 86146Beta-2 glycoproteinEach antibody class$25.45
- 86146 is for beta-2 glycoprotein antibody testing. Use 86148 when the measured antibody is directed against phosphatidylserine.
- 86147Cardiolipin antibodyEach immunoglobulin class$25.45
- 86147 reports cardiolipin antibody testing, not phosphatidylserine antibody testing.
- 85613Viper venom testDiluted clotting assay$9.58
- 85613 evaluates lupus anticoagulant using a coagulation-based test; 86148 measures antibodies directed against phosphatidylserine.
86148 billing questions
When should 86148 be used instead of 86147?
Use 86148 for an antibody measurement directed against phosphatidylserine. Code 86147 is for cardiolipin antibody testing.
How does 86148 differ from 86146?
86148 measures anti-phosphatidylserine antibodies; 86146 is for beta-2 glycoprotein antibody testing. They identify different antibody targets.
Does 86148 include other antiphospholipid antibody tests?
It reports the phosphatidylserine antibody measurement, not cardiolipin, beta-2 glycoprotein, or lupus anticoagulant testing.
What should the documentation identify?
Documentation should support that the laboratory measured phosphatidylserine antibodies, rather than a different antiphospholipid antibody target.
Does Medicare payment vary by locality or setting?
No. Medicare pays 86148 under the CLFS at one national amount across localities, without an office-versus-facility difference.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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