CPT code 86376: Microsomal antibody, thyroid or liver-kidney2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Measures microsomal autoantibodies, including thyroid and liver-kidney types, when one of these antibody targets is tested.
Medicare pays $14.55 for 86376 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$14.55
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 7 sections
What 86376 covers
86376 identifies measurement of microsomal autoantibodies, including thyroid microsomal and liver-kidney microsomal antibodies. It is reported when one of these antibody targets is measured as part of an evaluation for suspected autoimmune thyroid or liver disease. A clinical laboratory performs and reports the antibody measurement. The code's “each” distinction is by antibody target, including thyroid and liver-kidney microsomal antibodies.
Report the code for each microsomal antibody measured. Medicare pays 86376 under the CLFS, with one national amount per code across states and localities and no geographic or office/facility adjustment. The 2026 national CLFS amount is $14.55, unchanged from 2020 through 2026. Payment is only from the CLFS; the physician fee schedule does not pay the test.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 86376
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 86376. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 86376 with status X (excluded by statute), so the test itself is paid only from the CLFS.
86376 on the lab fee schedule since 2020
86376 · CLFS 2026 Q4 (current)
$14.55
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
86376 compared with similar tests
- 86381Mitochondrial antibodyEach antibody measured$25.45
- 86381 measures mitochondrial antibodies, a distinct target. Use 86376 for a microsomal antibody such as liver-kidney microsomal antibody.
- 86341Islet cell antibodyPancreatic islet antibodies$23.57
- 86341 measures islet-cell antibodies. It does not describe measurement of a thyroid or liver-kidney microsomal antibody.
- 86337Insulin antibodiesAntibodies directed at insulin$21.41
- 86337 measures insulin antibodies. Select it when insulin antibodies, rather than microsomal antibodies, are measured.
86376 billing questions
When should I report 86376 rather than another antibody code?
Use 86376 for a microsomal antibody measurement, such as a thyroid or liver-kidney microsomal antibody. Codes for mitochondrial, islet-cell, or insulin antibodies describe different targets.
What does “each” mean for this code?
The code identifies measurement of each microsomal antibody target. Thyroid and liver-kidney microsomal antibodies are examples of distinct targets.
Does 86376 identify a thyroid or liver-kidney antibody?
It can describe measurement of either target. The specific antibody measured should be identified in the laboratory documentation.
Does Medicare pay 86376 under the physician fee schedule?
No. Medicare pays this test under the CLFS.
What documentation supports reporting 86376?
Identify the microsomal antibody target measured, such as thyroid or liver-kidney microsomal antibody, and the clinical context for testing.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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