CPT code 87300: Polyvalent antigen test, multiple organisms, immunofluorescence2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Immunofluorescent antigen detection using polyvalent antiserum is reported for a laboratory test designed to detect multiple infectious organisms.
Medicare pays $11.98 for 87300 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$11.98
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 7 sections
What 87300 covers
Code 87300 represents laboratory detection of infectious-agent antigens by immunofluorescence with polyvalent antiserum. The reagent is used to detect multiple organisms, distinguishing this service from a test directed at one named organism. Report the test when the laboratory performs this polyvalent immunofluorescent antigen method.
Report one unit for each polyvalent antiserum used, not one unit for each organism it may detect. Medicare pays the test under the CLFS at one national amount across localities, with no office-versus-facility difference. The 2026 national amount is $11.98, unchanged since 2020. This amount applies in every state and locality. The test is paid through the CLFS and is excluded from the physician fee schedule.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 87300
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 87300. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 87300 with status X (excluded by statute), so the test itself is paid only from the CLFS.
87300 on the lab fee schedule since 2020
87300 · CLFS 2026 Q4 (current)
$11.98
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
87300 compared with similar tests
- 87301Adenovirus antigenEnteric types 40/41$11.98
- Code 87300 describes polyvalent immunofluorescent detection for multiple organisms. Code 87301 is adenovirus antigen testing by immunoassay.
- 87305Aspergillus antigenImmunoassay detection$11.98
- Code 87300 describes polyvalent immunofluorescent detection for multiple organisms. Code 87305 is Aspergillus antigen testing by immunoassay.
- 87324C. difficile toxin testStool toxin immunoassay$11.98
- Code 87300 describes polyvalent immunofluorescent detection for multiple organisms. Code 87324 is Clostridium antigen testing by immunoassay.
87300 billing questions
What method does 87300 describe?
It detects infectious-agent antigens by immunofluorescence using polyvalent antiserum for multiple organisms.
How are units counted?
Report one unit for each polyvalent antiserum used, not for each organism the antiserum may detect.
How does 87300 differ from an organism-specific antigen code?
Code 87300 describes polyvalent immunofluorescent detection for multiple organisms. An organism-specific code describes antigen testing directed at its named organism.
Does Medicare pay 87300 through the physician fee schedule?
No. Medicare pays the test under the CLFS, with one national amount across localities and no office-versus-facility difference.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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