CPT code 87305: Aspergillus antigen, immunoassay detection2026 Medicare lab fee · Clinical Laboratory Fee Schedule
An immunoassay for Aspergillus antigen, reported when evaluating a patient for Aspergillus infection, including suspected invasive disease.
Medicare pays $11.98 for 87305 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$11.98
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 87305 covers
This laboratory test detects Aspergillus antigen using an immunoassay and produces a qualitative or semiquantitative result. It may be ordered when a clinician is evaluating suspected Aspergillus infection, particularly invasive disease in an at-risk patient. Clinical laboratories perform the assay on submitted specimens, which may include serum or bronchoalveolar lavage fluid.
Report the code for the Aspergillus antigen assay performed; it is not a general fungal antigen panel or a culture. Medicare pays the test under the Clinical Laboratory Fee Schedule, with one national amount applying across localities and settings and no geographic or office-versus-facility adjustment. The 2026 national CLFS amount is $11.98, unchanged since 2020. The test is paid only through the CLFS; it has no separate physician fee schedule payment.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 87305
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 87305. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 87305 with status X (excluded by statute), so the test itself is paid only from the CLFS.
87305 on the lab fee schedule since 2020
87305 · CLFS 2026 Q4 (current)
$11.98
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
87305 compared with similar tests
- 87327Cryptococcus antigenMultistep immunoassay$13.42
- Choose 87305 for Aspergillus antigen and 87327 for Cryptococcus neoformans antigen. The organism being tested determines the code.
- 87385Histoplasma antigenQualitative or semiquantitative$13.25
- 87305 detects Aspergillus antigen; 87385 is for Histoplasma capsulatum antigen. Select the code matching the organism-specific assay.
- 87300Polyvalent antigen testMultiple organisms, immunofluorescence$11.98
- 87300 describes polyvalent infectious-agent antigen detection. Use 87305 when the assay specifically detects Aspergillus antigen.
87305 billing questions
When is this code appropriate?
Use it for an immunoassay that detects Aspergillus antigen. It is distinct from testing for other fungal antigens, such as Cryptococcus or Histoplasma.
Does this code describe a culture or a fungal panel?
No. It describes immunoassay detection of Aspergillus antigen, not fungal culture or a broad, polyvalent antigen assay.
What specimens may be tested?
Serum and bronchoalveolar lavage fluid are used for Aspergillus antigen testing. Report the assay performed on the submitted specimen.
How does Medicare pay for this test?
Medicare pays it through the CLFS at one national amount across localities and settings. There is no separate physician fee schedule payment for the test.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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