CPT code 87328: Cryptosporidium antigen, immunoassay detection2026 Medicare lab fee · Clinical Laboratory Fee Schedule
This laboratory test detects Cryptosporidium antigen by immunoassay for qualitative or semiquantitative assessment of the parasite.
Medicare pays $13.82 for 87328 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$13.82
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 87328 covers
Code 87328 identifies laboratory detection of Cryptosporidium, a parasite, by an antigen immunoassay. The result may be qualitative or semiquantitative. The assay may use an enzyme immunoassay, enzyme-linked immunosorbent assay, fluorescence immunoassay, or immunochemiluminometric method. It reports detection of Cryptosporidium antigen rather than identification of the organism by nucleic acid testing.
Medicare pays 87328 under the CLFS at one national amount in every state and locality, without a geographic or office/facility adjustment. The 2026 national amount is $13.82, unchanged since 2020. The test is paid only through the CLFS and is excluded from the physician fee schedule. Report the code for the Cryptosporidium antigen immunoassay performed; use a different code for another organism’s antigen assay or a multiplex nucleic acid assay.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 87328
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 87328. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 87328 with status X (excluded by statute), so the test itself is paid only from the CLFS.
87328 on the lab fee schedule since 2020
87328 · CLFS 2026 Q4 (current)
$13.82
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
87328 compared with similar tests
- 87329Giardia antigenImmunoassay detection$11.98
- Both are intestinal parasite antigen immunoassays, but 87328 detects Cryptosporidium and 87329 detects Giardia.
- 87336Entamoeba antigenHistolytica/dispar group$16.00
- Use 87328 for Cryptosporidium antigen; 87336 is for Entamoeba histolytica/dispar antigen.
- 87507GI pathogen panel12–25 targets$416.78
- 87328 is a single-organism antigen immunoassay. Code 87507 describes multiplex nucleic acid testing for gastrointestinal pathogens.
87328 billing questions
When should a biller choose 87328 rather than 87329?
Use 87328 for an assay detecting Cryptosporidium antigen. Code 87329 identifies Giardia antigen testing.
Is 87328 an antigen test or a molecular test?
It reports qualitative or semiquantitative antigen detection by immunoassay. A multiplex nucleic acid test is a different service.
Which immunoassay methods are included?
The test may use an enzyme immunoassay, enzyme-linked immunosorbent assay, fluorescence immunoassay, or immunochemiluminometric method.
How does Medicare pay for 87328?
Medicare pays it under the CLFS at one national amount, with no locality or office-versus-facility adjustment. It is paid only through the CLFS.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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