CPT code 88104: Fluid cytology, direct smear method2026 Medicare rate & RVUs in South Dakota

Reports cytologic examination and interpretation of direct smears made from non-gynecologic fluids, washings, or brushings, such as pleural fluid or bronchial washings.

CMS RVU26DEffective Oct 1, 2026One payment locality27.6K Medicare services in 2024

In South Dakota, Medicare pays $83.50 for 88104 in the office.

$83.50Office (non-facility)
Not available in this settingHospital or facility
−0.8%vs the national office rate ($84.17)

Check a contract rate as a % of Medicare · 88104 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88104 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in South Dakota
  2. What 88104 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88104 covers

This service covers cytologic examination of direct smears prepared from non-gynecologic fluids, washings, or brushings. Examples include pleural or peritoneal fluid, cerebrospinal fluid, and bronchial washings or brushings. Laboratory staff prepare and stain the slides, and a cytopathologist or other qualified physician examines the cells and provides the interpretation. The findings may help evaluate a specimen for malignant or other abnormal cells.

Choose this code when the specimen is examined as a smear rather than processed by a filtration, concentration, or cellular-enhancement method. The report should identify the specimen source and include the cytologic findings and physician interpretation. Medicare recognizes professional and technical components: modifier 26 identifies the interpretation, and modifier TC identifies the equipment and staff work. Reporting without either modifier represents the combined service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Dakota compares for 88104

Across 109 of 109 payment localities, the office rate for 88104 runs from $74.55 in Arkansas to $114.37 in San Benito County, CA. South Dakota pays $83.50. The RVUs are the same everywhere; the geographic indexes change the dollars.

88104 in South Dakota vs other payment areas
  1. South Dakota · this page$83.50
  2. Los Angeles, CA · California$96.44+$12.94
  3. Washington, DC area · District of Columbia$96.81+$13.31
  4. Miami, FL · Florida$88.36+$4.86
  5. Chicago, IL · Illinois$85.92+$2.42
  6. Manhattan, NY · New York$96.43+$12.93
  7. Alaska · Alaska$97.12+$13.62

Other areas in South Dakota first, then benchmark localities. Bars start at $0.

Every other payment area

88104 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$75.64—
ArkansasArkansas$74.55—
ArizonaArizona$82.02—
Bakersfield, CACalifornia$90.35—
Chico, CACalifornia$90.24—
El Centro, CACalifornia$90.24—
Fresno, CACalifornia$90.24—
Hanford, CACalifornia$90.24—

88104 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$74.55

$102.31

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88104 office rate range by state
State / territoryOffice rate rangeLocalities
AK$97.121
AL$75.641
AR$74.551
AZ$82.021
CA$90.24–$114.3729
CO$88.321
CT$89.741
DC$96.811
DE$83.381
FL$81.82–$88.363
GA$77.36–$85.462
GU$92.631
HI$92.631
IA$78.061
ID$78.461
IL$79.10–$86.824
IN$78.921
KS$77.451
KY$76.891
LA$76.68–$80.482
MA$87.70–$97.382
MD$85.05–$96.813
ME$78.61–$83.222
MI$78.66–$82.592
MN$85.341
MO$75.20–$81.063
MS$74.901
MT$84.171
NC$79.471
ND$83.581
NE$78.561
NH$86.701
NJ$90.96–$95.762
NM$78.991
NV$84.071
NY$80.63–$98.455
OH$78.541
OK$77.011
OR$83.61–$91.402
PA$78.80–$87.352
PR$84.871
RI$86.551
SC$79.101
SD$83.501
TN$77.811
TX$78.27–$87.858
UT$80.181
VA$82.77–$96.812
VI$84.871
VT$83.031
WA$87.60–$99.612
WI$80.761
WV$76.111
WY$83.911

See 88104 in every payment locality

How the 88104 rate is calculated

Each of 88104’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88104

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.55

0.55 RVUs× 1.000 GPCI

Practice expense1.94

1.94 RVUs× 1.000 GPCI

Malpractice0.03

0.03 RVUs× 1.000 GPCI

Adjusted RVUs

2.5200

Conversion factor

$33.4009

Medicare rate

$84.17

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact South Dakota inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,103

Code
88104
Physician work
0.55
Practice expense
1.94
Malpractice
0.03

GPCI2026.csv

94

Locality
South Dakota
Physician work
1.000
Practice expense
1.000
Malpractice
0.336
Office calculation for 88104 in South Dakota
ComponentRVULocality factorAdjusted
Physician work0.55× 1.0000.5500
Practice expense1.94× 1.0001.9400
Malpractice0.03× 0.3360.0101
Total RVUs2.5001
Conversion factor× 33.4009

Office rate, South Dakota$83.50

Office: (0.55 × 1 + 1.94 × 1 + 0.03 × 0.336) × $33.4009 = $83.50

Open 88104 in the RVU calculator

Payment rules and modifiers for 88104

The CMS indicators that decide how 88104 is paid alongside other services.

CMS payment indicators · 88104

Fluid cytology, direct smear method

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

88104 without 26 · national office

$84.17

Fluid cytology, direct smear method

88104-26 · Professional component

$26.72

Pays only the interpretation and report.

When to use modifier 26

How 88104 has changed in South Dakota

88104 · Office / nonfacility

$83.50

Effective 2026-10-01

The base rate is $6.47 higher than on 2025-10-01, moving from $77.03 to $83.50 (8.4%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $77.03changed to$83.50

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.56 changed to 0.55
    • Practice expense RVU 1.81 changed to 1.94
    • Malpractice GPCI 0.382 changed to 0.336

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $74.95changed to$77.03

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 1.68 changed to 1.81

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $73.72changed to$74.95

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $69.16changed to$73.72

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 1.47 changed to 1.68
    • Malpractice GPCI 0.364 changed to 0.382
  5. January 1, 2023

    RVU23A

    $67.72changed to$69.16

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 1.39 changed to 1.47
    • Malpractice RVU 0.02 changed to 0.03
    • Malpractice GPCI 0.347 changed to 0.364

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $66.89changed to$67.72

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 1.35 changed to 1.39

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $69.20changed to$66.89

    • Conversion factor 36.0896 changed to 34.8931
    • Malpractice GPCI 0.368 changed to 0.347

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $70.92changed to$69.20

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 1.40 changed to 1.35
    • Malpractice GPCI 0.389 changed to 0.368

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $73.72changed to$70.92

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 1.48 changed to 1.40

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $74.93changed to$73.72

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 1.52 changed to 1.48
    • Malpractice GPCI 0.395 changed to 0.389

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $76.19changed to$74.93

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 1.56 changed to 1.52
    • Malpractice GPCI 0.400 changed to 0.395

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $75.03changed to$76.19

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 1.52 changed to 1.56

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $74.66changed to$75.03

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $73.73changed to$74.66

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 1.49 changed to 1.52
    • Malpractice GPCI 0.416 changed to 0.400

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $75.83changed to$73.73

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 1.66 changed to 1.49
    • Malpractice GPCI 0.432 changed to 0.416

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $75.83

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$83.50Not available in this settingRVU26D
2026-07-01$83.50Not available in this settingRVU26C
2026-04-01$83.50Not available in this settingRVU26B
2026-01-01$83.50Not available in this settingRVU26A
2025-10-01$77.03Not available in this settingRVU25D
2025-07-01$77.03Not available in this settingRVU25C
2025-04-01$77.03Not available in this settingRVU25B
2025-01-01$77.03Not available in this settingRVU25A
2024-10-01$74.95Not available in this settingRVU24D
2024-07-01$74.95Not available in this settingRVU24C
2024-04-01$74.95Not available in this settingRVU24B
2024-03-09$74.95Not available in this settingRVU24AR
2024-01-01$73.72Not available in this settingRVU24A
2023-10-01$69.16Not available in this settingRVU23D
2023-07-01$69.16Not available in this settingRVU23C
2023-04-01$69.16Not available in this settingRVU23B
2023-01-01$69.16Not available in this settingRVU23A
2022-10-01$67.72Not available in this settingRVU22D
2022-07-01$67.72Not available in this settingRVU22C
2022-04-01$67.72Not available in this settingRVU22B
2022-01-01$67.72Not available in this settingRVU22A
2021-10-01$66.89Not available in this settingRVU21D
2021-07-01$66.89Not available in this settingRVU21C
2021-04-01$66.89Not available in this settingRVU21B
2021-01-01$66.89Not available in this settingRVU21A
2020-10-01$69.20Not available in this settingRVU20D
2020-07-01$69.20Not available in this settingRVU20C
2020-04-01$69.20Not available in this settingRVU20B
2020-01-01$69.20Not available in this settingRVU20A
2019-10-01$70.92Not available in this settingRVU19D
2019-07-01$70.92Not available in this settingRVU19C
2019-04-01$70.92Not available in this settingRVU19B
2019-01-01$70.92Not available in this settingRVU19A
2018-10-01$73.72Not available in this settingRVU18D
2018-07-01$73.72Not available in this settingRVU18C
2018-04-01$73.72Not available in this settingRVU18B
2018-01-01$73.72Not available in this settingRVU18AR1
2017-10-01$74.93Not available in this settingRVU17D
2017-07-01$74.93Not available in this settingRVU17C
2017-04-01$74.93Not available in this settingRVU17B
2017-01-01$74.93Not available in this settingRVU17A
2016-10-01$76.19Not available in this settingRVU16D
2016-07-01$76.19Not available in this settingRVU16C
2016-04-01$76.19Not available in this settingRVU16B
2016-01-01$76.19Not available in this settingRVU16A
2015-10-01$75.03Not available in this settingRVU15D
2015-07-01$75.03Not available in this settingRVU15C
2015-04-01$74.66Not available in this settingRVU15B
2015-01-01$74.66Not available in this settingRVU15A
2014-10-01$73.73Not available in this settingRVU14D
2014-07-01$73.73Not available in this settingRVU14C
2014-04-01$73.73Not available in this settingRVU14B
2014-01-01$73.73Not available in this settingRVU14A
2013-10-01$75.83Not available in this settingRVU13D
2013-07-01$75.83Not available in this settingRVU13C
2013-04-01$75.83Not available in this settingRVU13B
2013-01-01$75.83Not available in this settingRVU13AR

Price 88104 for an earlier date of service

Where the South Dakota rate applies

South Dakota is a Medicare payment area, not a city. Our Census mapping connects it to 485 cities and communities in South Dakota. Some span more than one payment area; confirm with the service ZIP.

  • Aberdeen
  • Agar
  • Agency Village
  • Akaska
  • Albee
  • Alcester
  • Alexandria
  • Allen

Browse all communities in South Dakota

88104 billing questions

When should 88104 be chosen instead of 88108?

Use 88104 for a direct smear of a non-gynecologic fluid, washing, or brushing. Use 88108 when the specimen is processed using a concentration technique.

Does 88104 include the physician's interpretation?

Yes. The service includes interpretation; modifier 26 reports the professional component alone, while modifier TC reports the technical component alone.

What does the technical component cover?

The technical component represents the equipment and staff work involved in the service. Modifier TC identifies that portion.

Can 88104 be reported for a cervical or vaginal smear?

No. This code is for non-gynecologic fluid, washing, or brushing smears; cervical and vaginal cytology uses the applicable gynecologic cytopathology code.

What specimen details should the report include?

Document the source and type of specimen, the smear preparation, and the cytologic findings with the physician's interpretation.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88104PPRRVU2026_Oct_nonQPP.csv, line 11,103 (RVU26D)
Geographic factors for South DakotaGPCI2026.csv, line 94 (RVU26D)

Open CMS sourceHow we calculate rates

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