CPT code 88160: Cytology smear, other source, screening and interpretation2026 Medicare rate & RVUs in Virginia

Use this code for screening and interpretation of a cytology smear from a non-cervical, non-vaginal source when the smear is already prepared.

CMS RVU26DEffective Oct 1, 2026One payment locality4.9K Medicare services in 2024

In Virginia, Medicare pays $80.11 for 88160 in the office.

$80.11Office (non-facility)
Not available in this settingHospital or facility
−1.7%vs the national office rate ($81.50)

Check a contract rate as a % of Medicare · 88160 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88160 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Virginia
  2. What 88160 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88160 covers

This service covers microscopic screening and interpretation of a smear made from a non-gynecologic specimen. Examples include smears from urine, sputum, or body-cavity fluid. A cytotechnologist may screen the slide, with a pathologist providing interpretation as needed. The code is relevant when the submitted material is a smear; it is not the cervical or vaginal cytology service or a fine-needle aspiration evaluation.

Choose the code based on the specimen source and the work performed. Documentation should identify the source, support that a smear was examined, and record the screening and interpretation. When the smear is already prepared, this code distinguishes the service from 88161, which includes preparation. CMS recognizes separately priced professional and technical components: modifier 26 reports the interpretation, modifier TC reports the technical component, and no component modifier represents the global service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Virginia compares for 88160

Across 109 of 109 payment localities, the office rate for 88160 runs from $71.97 in Arkansas to $111.18 in San Benito County, CA. Virginia pays $80.11. The RVUs are the same everywhere; the geographic indexes change the dollars.

88160 in Virginia vs other payment areas
  1. Virginia · this page$80.11
  2. Los Angeles, CA · California$93.57+$13.46
  3. Washington, DC area · District of Columbia$93.91+$13.80
  4. Miami, FL · Florida$85.66+$5.55
  5. Chicago, IL · Illinois$83.23+$3.12
  6. Manhattan, NY · New York$93.52+$13.41
  7. Alaska · Alaska$93.40+$13.29

Other areas in Virginia first, then benchmark localities. Bars start at $0.

Every other payment area

88160 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$73.05—
ArkansasArkansas$71.97—
ArizonaArizona$79.37—
Bakersfield, CACalifornia$87.57—
Chico, CACalifornia$87.47—
El Centro, CACalifornia$87.47—
Fresno, CACalifornia$87.47—
Hanford, CACalifornia$87.47—

88160 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$71.97

$99.33

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88160 office rate range by state
State / territoryOffice rate rangeLocalities
AK$93.401
AL$73.051
AR$71.971
AZ$79.371
CA$87.47–$111.1829
CO$85.581
CT$86.971
DC$93.911
DE$80.711
FL$79.18–$85.663
GA$74.76–$82.772
GU$89.861
HI$89.861
IA$75.441
ID$75.841
IL$76.48–$84.124
IN$76.301
KS$74.841
KY$74.291
LA$74.08–$77.852
MA$84.96–$94.502
MD$82.35–$93.913
ME$75.99–$80.552
MI$76.05–$79.942
MN$82.651
MO$72.62–$78.423
MS$72.321
MT$81.501
NC$76.841
ND$80.901
NE$75.941
NH$84.001
NJ$88.15–$92.862
NM$76.381
NV$81.391
NY$77.99–$95.525
OH$75.931
OK$74.411
OR$80.94–$88.622
PA$76.18–$84.622
PR$82.191
RI$83.821
SC$76.471
SD$80.831
TN$75.201
TX$75.66–$85.148
UT$77.551
VA$80.11–$93.912
VI$82.191
VT$80.361
WA$84.87–$96.692
WI$78.111
WV$73.531
WY$81.241

See 88160 in every payment locality

How the 88160 rate is calculated

Each of 88160’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88160

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.49

0.49 RVUs× 1.000 GPCI

Practice expense1.92

1.92 RVUs× 1.000 GPCI

Malpractice0.03

0.03 RVUs× 1.000 GPCI

Adjusted RVUs

2.4400

Conversion factor

$33.4009

Medicare rate

$81.50

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Virginia inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,135

Code
88160
Physician work
0.49
Practice expense
1.92
Malpractice
0.03

GPCI2026.csv

106

Locality
Virginia
Physician work
1.000
Practice expense
0.983
Malpractice
0.706
Office calculation for 88160 in Virginia
ComponentRVULocality factorAdjusted
Physician work0.49× 1.0000.4900
Practice expense1.92× 0.9831.8874
Malpractice0.03× 0.7060.0212
Total RVUs2.3985
Conversion factor× 33.4009

Office rate, Virginia$80.11

Office: (0.49 × 1 + 1.92 × 0.983 + 0.03 × 0.706) × $33.4009 = $80.11

Open 88160 in the RVU calculator

Payment rules and modifiers for 88160

The CMS indicators that decide how 88160 is paid alongside other services.

CMS payment indicators · 88160

Cytology smear, other source, screening and interpretation

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

88160 without 26 · national office

$81.50

Cytology smear, other source, screening and interpretation

88160-26 · Professional component

$24.05

Pays only the interpretation and report.

When to use modifier 26

How 88160 has changed in Virginia

88160 · Office / nonfacility

$80.11

Effective 2026-10-01

The base rate is $0.47 higher than on 2025-10-01, moving from $79.64 to $80.11 (0.6%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $79.64changed to$80.11

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.50 changed to 0.49
    • Practice expense RVU 1.97 changed to 1.92
    • Work GPCI 1.002 changed to 1.000
    • Practice expense GPCI 0.984 changed to 0.983
    • Malpractice GPCI 0.755 changed to 0.706

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $78.36changed to$79.64

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 1.86 changed to 1.97

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $77.08changed to$78.36

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $75.15changed to$77.08

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 1.71 changed to 1.86
    • Work GPCI 1.000 changed to 1.002
    • Practice expense GPCI 0.990 changed to 0.984
    • Malpractice GPCI 0.826 changed to 0.755
  5. January 1, 2023

    RVU23A

    $72.33changed to$75.15

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 1.58 changed to 1.71
    • Malpractice RVU 0.02 changed to 0.03
    • Practice expense GPCI 0.995 changed to 0.990
    • Malpractice GPCI 0.897 changed to 0.826

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $71.54changed to$72.33

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 1.54 changed to 1.58

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $71.99changed to$71.54

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 1.49 changed to 1.54
    • Practice expense GPCI 0.991 changed to 0.995
    • Malpractice GPCI 0.903 changed to 0.897

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $71.62changed to$71.99

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense GPCI 0.986 changed to 0.991
    • Malpractice GPCI 0.908 changed to 0.903

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $73.32changed to$71.62

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 1.54 changed to 1.49

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $72.65changed to$73.32

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 1.53 changed to 1.54
    • Practice expense GPCI 0.985 changed to 0.986
    • Malpractice GPCI 0.866 changed to 0.908

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $71.99changed to$72.65

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 1.52 changed to 1.53
    • Practice expense GPCI 0.983 changed to 0.985
    • Malpractice GPCI 0.824 changed to 0.866

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $66.60changed to$71.99

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 1.36 changed to 1.52

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $66.27changed to$66.60

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $63.40changed to$66.27

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 1.28 changed to 1.36
    • Practice expense GPCI 0.980 changed to 0.983
    • Malpractice GPCI 0.778 changed to 0.824

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $62.38changed to$63.40

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 1.35 changed to 1.28
    • Practice expense GPCI 0.977 changed to 0.980
    • Malpractice GPCI 0.731 changed to 0.778

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $62.38

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$80.11Not available in this settingRVU26D
2026-07-01$80.11Not available in this settingRVU26C
2026-04-01$80.11Not available in this settingRVU26B
2026-01-01$80.11Not available in this settingRVU26A
2025-10-01$79.64Not available in this settingRVU25D
2025-07-01$79.64Not available in this settingRVU25C
2025-04-01$79.64Not available in this settingRVU25B
2025-01-01$79.64Not available in this settingRVU25A
2024-10-01$78.36Not available in this settingRVU24D
2024-07-01$78.36Not available in this settingRVU24C
2024-04-01$78.36Not available in this settingRVU24B
2024-03-09$78.36Not available in this settingRVU24AR
2024-01-01$77.08Not available in this settingRVU24A
2023-10-01$75.15Not available in this settingRVU23D
2023-07-01$75.15Not available in this settingRVU23C
2023-04-01$75.15Not available in this settingRVU23B
2023-01-01$75.15Not available in this settingRVU23A
2022-10-01$72.33Not available in this settingRVU22D
2022-07-01$72.33Not available in this settingRVU22C
2022-04-01$72.33Not available in this settingRVU22B
2022-01-01$72.33Not available in this settingRVU22A
2021-10-01$71.54Not available in this settingRVU21D
2021-07-01$71.54Not available in this settingRVU21C
2021-04-01$71.54Not available in this settingRVU21B
2021-01-01$71.54Not available in this settingRVU21A
2020-10-01$71.99Not available in this settingRVU20D
2020-07-01$71.99Not available in this settingRVU20C
2020-04-01$71.99Not available in this settingRVU20B
2020-01-01$71.99Not available in this settingRVU20A
2019-10-01$71.62Not available in this settingRVU19D
2019-07-01$71.62Not available in this settingRVU19C
2019-04-01$71.62Not available in this settingRVU19B
2019-01-01$71.62Not available in this settingRVU19A
2018-10-01$73.32Not available in this settingRVU18D
2018-07-01$73.32Not available in this settingRVU18C
2018-04-01$73.32Not available in this settingRVU18B
2018-01-01$73.32Not available in this settingRVU18AR1
2017-10-01$72.65Not available in this settingRVU17D
2017-07-01$72.65Not available in this settingRVU17C
2017-04-01$72.65Not available in this settingRVU17B
2017-01-01$72.65Not available in this settingRVU17A
2016-10-01$71.99Not available in this settingRVU16D
2016-07-01$71.99Not available in this settingRVU16C
2016-04-01$71.99Not available in this settingRVU16B
2016-01-01$71.99Not available in this settingRVU16A
2015-10-01$66.60Not available in this settingRVU15D
2015-07-01$66.60Not available in this settingRVU15C
2015-04-01$66.27Not available in this settingRVU15B
2015-01-01$66.27Not available in this settingRVU15A
2014-10-01$63.40Not available in this settingRVU14D
2014-07-01$63.40Not available in this settingRVU14C
2014-04-01$63.40Not available in this settingRVU14B
2014-01-01$63.40Not available in this settingRVU14A
2013-10-01$62.38Not available in this settingRVU13D
2013-07-01$62.38Not available in this settingRVU13C
2013-04-01$62.38Not available in this settingRVU13B
2013-01-01$62.38Not available in this settingRVU13AR

Price 88160 for an earlier date of service

Where the Virginia rate applies

Virginia is a Medicare payment area, not a city. Our Census mapping connects it to 628 cities and communities in Virginia. Some span more than one payment area; confirm with the service ZIP.

  • Abbs Valley
  • Abingdon
  • Accomac
  • Adwolf
  • Afton
  • Alberta
  • Aldie
  • Allison Gap

Browse all communities in Virginia

88160 billing questions

How does 88160 differ from 88161?

88160 is for screening and interpretation of an already prepared smear. 88161 includes preparation as well as screening and interpretation.

Can 88160 be used for a cervical or vaginal smear?

No. This code is for smears from other sources; cervical or vaginal cytology belongs to the applicable gynecologic cytology code.

Which modifiers identify the components?

Modifier 26 reports the professional interpretation, and modifier TC reports the technical component. Reporting without either modifier represents the global service.

What specimen details support reporting this code?

Document the specimen source and that a prepared smear was screened and interpreted. The record should make clear that the specimen is not cervical or vaginal.

Is this the code for fine-needle aspiration evaluation?

No. Fine-needle aspiration evaluation uses codes specific to that service; 88160 describes screening and interpretation of a smear from another source.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88160PPRRVU2026_Oct_nonQPP.csv, line 11,135 (RVU26D)
Geographic factors for VirginiaGPCI2026.csv, line 106 (RVU26D)

Open CMS sourceHow we calculate rates

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