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CPT code 88182: Cell marker study, limited analysis2026 Medicare rate & RVUs in Ohio

Reports a limited cell-marker analysis, such as DNA ploidy, cell-cycle analysis, or immunocytochemistry, on a specimen submitted for diagnostic evaluation.

CMS RVU26DEffective Oct 1, 2026One payment locality2.3K Medicare services in 2024

In Ohio, Medicare pays $138.38 for 88182 in the office.

$138.38Office (non-facility)
Not available in this settingHospital or facility
−7.1%vs the national office rate ($148.97)

Check a contract rate as a % of Medicare · 88182 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88182 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Ohio
  2. What 88182 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88182 covers

This service covers a limited analysis of cells using markers or related measurements, including DNA ploidy, cell-cycle analysis, or immunocytochemistry. It is performed in a pathology or cytology laboratory, with laboratory staff and equipment supporting the technical work and a pathologist or other qualified professional interpreting the findings. It may be used to characterize tumor cells or other diagnostically relevant cells in a submitted specimen.

Report the service for each specimen that receives the limited study, rather than counting individual markers as separate units. Documentation should identify the specimen, the type and purpose of the analysis, and the resulting interpretation. CMS recognizes separate professional and technical components: modifier 26 identifies interpretation, modifier TC identifies the equipment and staff portion, and reporting without either modifier represents the global service. The professional and technical components are separately priced when billed with their respective modifiers.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Ohio compares for 88182

Across 109 of 109 payment localities, the office rate for 88182 runs from $130.81 in Arkansas to $204.68 in San Benito County, CA. Ohio pays $138.38. The RVUs are the same everywhere; the geographic indexes change the dollars.

88182 in Ohio vs other payment areas
  1. Ohio · this page$138.38
  2. Los Angeles, CA · California$171.63+$33.25
  3. Washington, DC area · District of Columbia$172.25+$33.87
  4. Miami, FL · Florida$157.03+$18.65
  5. Chicago, IL · Illinois$152.35+$13.97
  6. Manhattan, NY · New York$171.50+$33.12
  7. Alaska · Alaska$168.52+$30.14

Other areas in Ohio first, then benchmark localities. Bars start at $0.

Every other payment area

88182 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$132.86—
ArkansasArkansas$130.81—
ArizonaArizona$144.90—
Bakersfield, CACalifornia$160.36—
Chico, CACalifornia$160.17—
El Centro, CACalifornia$160.18—
Fresno, CACalifornia$160.17—
Hanford, CACalifornia$160.17—

88182 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$130.81

$182.43

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88182 office rate range by state
State / territoryOffice rate rangeLocalities
AK$168.521
AL$132.861
AR$130.811
AZ$144.901
CA$160.17–$204.6829
CO$156.631
CT$159.281
DC$172.251
DE$147.431
FL$144.61–$157.033
GA$136.19–$151.402
GU$164.831
HI$164.831
IA$137.401
ID$138.161
IL$139.49–$153.984
IN$139.041
KS$136.271
KY$135.271
LA$134.86–$142.052
MA$155.42–$173.432
MD$150.52–$172.253
ME$138.46–$147.132
MI$138.62–$146.082
MN$151.091
MO$132.09–$143.123
MS$131.501
MT$148.961
NC$140.081
ND$147.781
NE$138.331
NH$153.721
NJ$161.38–$170.192
NM$139.251
NV$148.761
NY$142.28–$175.335
OH$138.381
OK$135.481
OR$147.89–$162.392
PA$138.86–$154.802
PR$150.281
RI$153.251
SC$139.401
SD$147.641
TN$136.951
TX$137.85–$155.868
UT$141.451
VA$146.31–$172.252
VI$150.281
VT$146.761
WA$155.28–$177.532
WI$142.461
WV$133.861
WY$148.451

See 88182 in every payment locality

How the 88182 rate is calculated

Each of 88182’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88182

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.75

0.75 RVUs× 1.000 GPCI

Practice expense3.65

3.65 RVUs× 1.000 GPCI

Malpractice0.06

0.06 RVUs× 1.000 GPCI

Adjusted RVUs

4.4600

Conversion factor

$33.4009

Medicare rate

$148.97

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Ohio inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,159

Code
88182
Physician work
0.75
Practice expense
3.65
Malpractice
0.06

GPCI2026.csv

85

Locality
Ohio
Physician work
1.000
Practice expense
0.913
Malpractice
1.008
Office calculation for 88182 in Ohio
ComponentRVULocality factorAdjusted
Physician work0.75× 1.0000.7500
Practice expense3.65× 0.9133.3325
Malpractice0.06× 1.0080.0605
Total RVUs4.1429
Conversion factor× 33.4009

Office rate, Ohio$138.38

Office: (0.75 × 1 + 3.65 × 0.913 + 0.06 × 1.008) × $33.4009 = $138.38

Open 88182 in the RVU calculator

Payment rules and modifiers for 88182

The CMS indicators that decide how 88182 is paid alongside other services.

CMS payment indicators · 88182

Cell marker study, limited analysis

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

88182 without 26 · national office

$148.97

Cell marker study, limited analysis

88182-26 · Professional component

$35.07

Pays only the interpretation and report.

When to use modifier 26

Codes related to 88182

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 88182
CodeHow it relatesOffice range, Ohio
Used instead
88184Flow cytometry, first marker, technical componentUsed for the technical work on the first marker when the study is performed by flow cytometry.$74.17
88187Flow cytometry, 2–8 marker interpretationReports interpretation of flow cytometry with 2–8 markers, rather than a limited cell-marker study.$34.21
88188Flow cytometry, 9–15 markersReports interpretation of flow cytometry with 9–15 markers.$56.96
88189Flow cytometry, 16 or more markersReports interpretation of flow cytometry with 16 or more markers.$77.32

How 88182 has changed in Ohio

88182 · Office / nonfacility

$138.38

Effective 2026-10-01

The base rate is $5.77 lower than on 2025-10-01, moving from $144.15 to $138.38 (4.0%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $144.15changed to$138.38

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.77 changed to 0.75
    • Practice expense RVU 3.99 changed to 3.65
    • Malpractice RVU 0.05 changed to 0.06
    • Practice expense GPCI 0.911 changed to 0.913
    • Malpractice GPCI 1.033 changed to 1.008

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $154.45changed to$144.15

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 4.18 changed to 3.99
    • Malpractice RVU 0.06 changed to 0.05

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $151.93changed to$154.45

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $150.28changed to$151.93

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 3.96 changed to 4.18
    • Malpractice RVU 0.05 changed to 0.06
    • Practice expense GPCI 0.912 changed to 0.911
    • Malpractice GPCI 1.063 changed to 1.033

  5. January 1, 2023

    RVU23A

    $138.81changed to$150.28

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 3.49 changed to 3.96
    • Practice expense GPCI 0.913 changed to 0.912
    • Malpractice GPCI 1.094 changed to 1.063

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $131.04changed to$138.81

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 3.21 changed to 3.49

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $131.01changed to$131.04

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 3.08 changed to 3.21
    • Malpractice RVU 0.04 changed to 0.05
    • Practice expense GPCI 0.915 changed to 0.913
    • Malpractice GPCI 1.049 changed to 1.094

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $127.71changed to$131.01

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 2.97 changed to 3.08
    • Malpractice RVU 0.05 changed to 0.04
    • Practice expense GPCI 0.917 changed to 0.915
    • Malpractice GPCI 1.005 changed to 1.049

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $125.26changed to$127.71

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 2.90 changed to 2.97

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $113.74changed to$125.26

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 2.57 changed to 2.90
    • Malpractice RVU 0.04 changed to 0.05
    • Practice expense GPCI 0.918 changed to 0.917
    • Malpractice GPCI 0.999 changed to 1.005

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $106.23changed to$113.74

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 2.35 changed to 2.57
    • Malpractice GPCI 0.993 changed to 0.999

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $102.66changed to$106.23

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 2.23 changed to 2.35

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $102.15changed to$102.66

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $104.05changed to$102.15

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 2.24 changed to 2.23
    • Malpractice RVU 0.06 changed to 0.04
    • Practice expense GPCI 0.923 changed to 0.918
    • Malpractice GPCI 1.117 changed to 0.993

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $103.79changed to$104.05

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 2.38 changed to 2.24
    • Practice expense GPCI 0.927 changed to 0.923
    • Malpractice GPCI 1.240 changed to 1.117

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $103.79

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$138.38Not available in this settingRVU26D
2026-07-01$138.38Not available in this settingRVU26C
2026-04-01$138.38Not available in this settingRVU26B
2026-01-01$138.38Not available in this settingRVU26A
2025-10-01$144.15Not available in this settingRVU25D
2025-07-01$144.15Not available in this settingRVU25C
2025-04-01$144.15Not available in this settingRVU25B
2025-01-01$144.15Not available in this settingRVU25A
2024-10-01$154.45Not available in this settingRVU24D
2024-07-01$154.45Not available in this settingRVU24C
2024-04-01$154.45Not available in this settingRVU24B
2024-03-09$154.45Not available in this settingRVU24AR
2024-01-01$151.93Not available in this settingRVU24A
2023-10-01$150.28Not available in this settingRVU23D
2023-07-01$150.28Not available in this settingRVU23C
2023-04-01$150.28Not available in this settingRVU23B
2023-01-01$150.28Not available in this settingRVU23A
2022-10-01$138.81Not available in this settingRVU22D
2022-07-01$138.81Not available in this settingRVU22C
2022-04-01$138.81Not available in this settingRVU22B
2022-01-01$138.81Not available in this settingRVU22A
2021-10-01$131.04Not available in this settingRVU21D
2021-07-01$131.04Not available in this settingRVU21C
2021-04-01$131.04Not available in this settingRVU21B
2021-01-01$131.04Not available in this settingRVU21A
2020-10-01$131.01Not available in this settingRVU20D
2020-07-01$131.01Not available in this settingRVU20C
2020-04-01$131.01Not available in this settingRVU20B
2020-01-01$131.01Not available in this settingRVU20A
2019-10-01$127.71Not available in this settingRVU19D
2019-07-01$127.71Not available in this settingRVU19C
2019-04-01$127.71Not available in this settingRVU19B
2019-01-01$127.71Not available in this settingRVU19A
2018-10-01$125.26Not available in this settingRVU18D
2018-07-01$125.26Not available in this settingRVU18C
2018-04-01$125.26Not available in this settingRVU18B
2018-01-01$125.26Not available in this settingRVU18AR1
2017-10-01$113.74Not available in this settingRVU17D
2017-07-01$113.74Not available in this settingRVU17C
2017-04-01$113.74Not available in this settingRVU17B
2017-01-01$113.74Not available in this settingRVU17A
2016-10-01$106.23Not available in this settingRVU16D
2016-07-01$106.23Not available in this settingRVU16C
2016-04-01$106.23Not available in this settingRVU16B
2016-01-01$106.23Not available in this settingRVU16A
2015-10-01$102.66Not available in this settingRVU15D
2015-07-01$102.66Not available in this settingRVU15C
2015-04-01$102.15Not available in this settingRVU15B
2015-01-01$102.15Not available in this settingRVU15A
2014-10-01$104.05Not available in this settingRVU14D
2014-07-01$104.05Not available in this settingRVU14C
2014-04-01$104.05Not available in this settingRVU14B
2014-01-01$104.05Not available in this settingRVU14A
2013-10-01$103.79Not available in this settingRVU13D
2013-07-01$103.79Not available in this settingRVU13C
2013-04-01$103.79Not available in this settingRVU13B
2013-01-01$103.79Not available in this settingRVU13AR

Price 88182 for an earlier date of service

Where the Ohio rate applies

Ohio is a Medicare payment area, not a city. Our Census mapping connects it to 1265 cities and communities in Ohio. Some span more than one payment area; confirm with the service ZIP.

  • Aberdeen
  • Ada
  • Adamsville
  • Addyston
  • Adelphi
  • Adena
  • Ai
  • Akron

Browse all communities in Ohio

88182 billing questions

When should 88182 be chosen instead of a flow cytometry code?

Use 88182 for a limited cell-marker study such as DNA ploidy, cell-cycle analysis, or immunocytochemistry. Flow cytometry procedures are reported with codes specific to their technical marker work and interpretation.

How many units should be reported?

Report one unit for each specimen receiving the limited study. Do not use the number of markers as the unit count.

Can the professional and technical portions be billed separately?

Yes. Modifier 26 identifies the professional interpretation, and modifier TC identifies the technical work. Without either modifier, the claim represents the global service.

What documentation supports 88182?

Document the specimen, the limited study performed, its diagnostic purpose, and the interpretation. The record should make clear that the work was a limited cell-marker analysis rather than flow cytometry marker testing.

Is 88182 reported once per marker?

No. For this code, the unit is the specimen receiving the limited analysis, not each marker assessed.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88182PPRRVU2026_Oct_nonQPP.csv, line 11,159 (RVU26D)
Geographic factors for OhioGPCI2026.csv, line 85 (RVU26D)

Open CMS sourceHow we calculate rates

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