FeeBase
Log inGet started
Menu

CPT code 88299: Cytogenetic study, unlisted service2026 Medicare rate & RVUs

An unlisted cytogenetic laboratory service reported when no specific CPT code describes the chromosome or cellular genetic analysis performed.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare rate · 88299

Cytogenetic study, unlisted service

Office or facility?

Work RVUs
0
Total RVUs
0.00
Global days
XXX

National rate · 2026

—

Not priced in the facility setting.

See every locality for 88299 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What 88299 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 88299 covers

CPT 88299 identifies a cytogenetic laboratory study that lacks a more specific listed procedure code. Cytogenetics laboratories assess chromosome structure or other cellular genetic features in testing ordered to investigate genetic or chromosomal conditions. The laboratory that performs the study reports the service. Select a listed code whenever its defined study matches the work performed; 88299 is for work not represented by a specific cytogenetic procedure code.

For Medicare, 88299 is carrier-priced (status C): CMS publishes no national payment, and the Medicare Administrative Contractor sets payment for each claim. The claim should identify the study performed and include information that lets the contractor assess the service represented. This payment status does not make 88299 a substitute for a listed cytogenetic procedure code that fits the work.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 88299 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

88299 office and facility rates by payment locality
Payment localityOfficeFacility
AlabamaUnavailableUnavailable
AlaskaUnavailableUnavailable
ArizonaUnavailableUnavailable
ArkansasUnavailableUnavailable
Atlanta, GAUnavailableUnavailable
Austin, TXUnavailableUnavailable
Bakersfield, CAUnavailableUnavailable
Baltimore area, MDUnavailableUnavailable
Beaumont, TXUnavailableUnavailable
Brazoria, TXUnavailableUnavailable

88299 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

View every state and territory as a table
88299 office rate range by state
State / territoryOffice rate rangeLocalities
AKNo published base rate1
ALNo published base rate1
ARNo published base rate1
AZNo published base rate1
CANo published base rate29
CONo published base rate1
CTNo published base rate1
DCNo published base rate1
DENo published base rate1
FLNo published base rate3
GANo published base rate2
GUNo published base rate1
HINo published base rate1
IANo published base rate1
IDNo published base rate1
ILNo published base rate4
INNo published base rate1
KSNo published base rate1
KYNo published base rate1
LANo published base rate2
MANo published base rate2
MDNo published base rate3
MENo published base rate2
MINo published base rate2
MNNo published base rate1
MONo published base rate3
MSNo published base rate1
MTNo published base rate1
NCNo published base rate1
NDNo published base rate1
NENo published base rate1
NHNo published base rate1
NJNo published base rate2
NMNo published base rate1
NVNo published base rate1
NYNo published base rate5
OHNo published base rate1
OKNo published base rate1
ORNo published base rate2
PANo published base rate2
PRNo published base rate1
RINo published base rate1
SCNo published base rate1
SDNo published base rate1
TNNo published base rate1
TXNo published base rate8
UTNo published base rate1
VANo published base rate2
VINo published base rate1
VTNo published base rate1
WANo published base rate2
WINo published base rate1
WVNo published base rate1
WYNo published base rate1

How the 88299 rate is calculated

Each of 88299’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88299

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense0.00

0.00 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

0.0000

Conversion factor

$33.4009

Medicare rate

$0.00

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 88299

88299 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · 88299

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

—

88299 isn’t priced in this setting.

88299 compared with similar codes

Compare codes · National

5 codes, side by side

Office or facility?

  • 88299

    Cytogenetic study, unlisted service0 wRVU

    Not priced

  • 88271

    DNA probe, each probeLab fee

    $21.42

  • 88280

    Karyotype study, additional studyLab fee

    $33.47

  • 88283

    Chromosome banding, specialized techniqueLab fee

    $68.60

  • 88291

    Cytogenetic report, interpretation and report0.51 wRVU

    $33.07

How to choose

88271DNA probeEach probe
Use 88271 for a cytogenetic DNA probe study that fits that code. Use 88299 only when no specific listed code describes the study.
88280Karyotype studyAdditional study
88280 describes a chromosome karyotype study. 88299 is for a cytogenetic study without a more specific procedure code.
88283Chromosome bandingSpecialized technique
88283 is the specific code for a chromosome banding study; 88299 is not a substitute when banding describes the work.
88291Cytogenetic reportInterpretation and report
88291 identifies a cytogenetic or molecular cytogenetic report. 88299 represents an unlisted study, not the reporting service itself.

Codes related to 88299

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 88299
CodeHow it relatesNational office range
Used instead
88271DNA probe, each probeUse for a cytogenetic DNA probe study when that specific procedure describes the service.$21.42
88280Karyotype study, additional studyUse for a chromosome karyotype study when that listed procedure describes the service.$33.47
88283Chromosome banding, specialized techniqueUse for a chromosome banding study when that listed procedure describes the service.$68.60
88262Chromosome analysis, 15–20 cells, two karyotypesUse when the listed chromosome analysis code matches the study performed.$125.49
88269Amniotic karyotype, six to 12 coloniesUse for chromosome analysis of amniotic material when that procedure describes the service.$173.66

88299 billing questions

When should the laboratory use 88299 instead of a listed cytogenetics code?

Use 88299 when no specific CPT code describes the cytogenetic study performed. Report a listed code when its defined study matches the work.

What information should accompany a claim for 88299?

Identify the study performed and provide information that distinguishes the work from listed cytogenetic procedures.

How does Medicare price 88299?

It has carrier-priced status: CMS publishes no national payment, and the Medicare Administrative Contractor sets payment for each claim.

Can 88299 replace a listed chromosome or probe code?

No. Use a listed code when it describes the study performed; reserve 88299 for a cytogenetic service without a more specific code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

Did this answer your question about what 88299 pays?

Tell us what you were actually trying to work out. We’ll answer you directly, or build the page that does.

Fee sheets · Coming soon

Put 88299 and the rest of your codes on one sheet

Your codes at your locality, with payer contracts beside Medicare.

Join the waitlist