CPT code 88321: Slide consultation, outside-prepared slides2026 Medicare rate & RVUs

A pathologist reviews slides prepared by another laboratory and issues a consultation report, commonly for an outside second opinion on biopsy or resection findings.

CMS RVU26DEffective Oct 1, 2026109 payment localities161.7K Medicare services in 2024

Medicare pays $93.86 for 88321 nationally in the office and $67.47 in a hospital or facility. Local office rates run $87.31–$121.86.

Medicare rate · 88321

Slide consultation, outside-prepared slides

Office or facility?

Work RVUs
1.59
Total RVUs
2.81
Global days
XXX

National rate · 2026

$93.86

Office setting, before claim adjustments.

See every locality for 88321 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What 88321 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 88321 covers

A pathologist examines slides that another laboratory has already prepared and provides an interpretive consultation report. A common situation is a treating clinician requesting an outside review of biopsy or resection slides before deciding on diagnosis or treatment. The service is performed by a pathologist in a hospital, reference laboratory, or other pathology practice; it is not the preparation of new slides from submitted tissue.

Select this code when the consultation is based on slides prepared elsewhere. The report should identify the material reviewed and document the pathologist’s interpretation and conclusions. Use a different consultation code when the referred material requires preparation or when the service involves a broader review of records and specimens. This code represents the slide-review consultation, rather than the original laboratory’s tissue examination or a stain service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 88321 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$87.31 to $121.86

$87.31$104.59$121.86
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

88321 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$88.04$64.95
Alaska$121.86$93.76
Arizona$92.33$66.76
Arkansas$87.31$64.64
Atlanta, GA$95.10$68.29
Austin, TX$95.92$68.01
Bakersfield, CA$97.64$68.72
Baltimore area, MD$98.06$69.75
Beaumont, TX$90.23$66.22
Brazoria, TX$93.42$67.27

88321 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$87.31

$121.86

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88321 office rate range by state
State / territoryOffice rate rangeLocalities
AK$121.861
AL$88.041
AR$87.311
AZ$92.331
CA$97.36–$115.5929
CO$96.441
CT$98.371
DC$103.831
DE$93.421
FL$93.34–$99.013
GA$90.16–$95.102
GU$98.131
HI$98.131
IA$89.181
ID$89.551
IL$91.83–$97.454
IN$89.851
KS$89.011
KY$89.391
LA$89.34–$91.912
MA$96.27–$103.232
MD$94.66–$103.833
ME$89.90–$92.652
MI$90.82–$94.122
MN$93.321
MO$88.50–$92.023
MS$87.911
MT$93.851
NC$90.441
ND$92.471
NE$89.441
NH$95.141
NJ$99.74–$103.512
NM$91.141
NV$93.501
NY$91.24–$106.525
OH$90.531
OK$89.231
OR$93.01–$98.372
PA$90.58–$96.842
PR$94.241
RI$95.881
SC$90.591
SD$92.301
TN$89.281
TX$90.23–$95.928
UT$91.311
VA$92.52–$103.832
VI$94.241
VT$92.321
WA$96.02–$104.802
WI$90.631
WV$89.831
WY$93.251

How the 88321 rate is calculated

Each of 88321’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88321

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.59

1.59 RVUs× 1.000 GPCI

Practice expense1.15

1.15 RVUs× 1.000 GPCI

Malpractice0.07

0.07 RVUs× 1.000 GPCI

Adjusted RVUs

2.8100

Conversion factor

$33.4009

Medicare rate

$93.86

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 88321

88321 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · 88321

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

$93.86

Non-facility (office)
$93.86
Facility
$67.47

Higher because the practice carries its own overhead.

88321 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 88321

    Slide consultation, outside-prepared slides1.59 wRVU

    $93.86

  • 88323

    Pathology consultation, referred material, slides prepared1.78 wRVU

    $112.90+$19.04

  • 88325

    Pathology consultation, comprehensive record review2.78 wRVU

    $153.31+$59.45

  • 88329

    Pathology consult, gross examination only0.65 wRVU

    $52.11−$41.75

How to choose

88323Pathology consultationReferred material, slides prepared
Choose 88321 for slides prepared by another laboratory. Choose 88323 when the referred material requires preparation for the consultation.
88325Pathology consultationComprehensive record review
88321 centers on review of outside-prepared slides; 88325 describes a comprehensive review of records and specimens.
88329Pathology consultGross examination only
88329 is for a pathology consultation during surgery. 88321 is for a consultation report based on slides prepared elsewhere.

88321 billing questions

How does this differ from 88323?

Use 88321 when the slides were already prepared elsewhere. Code 88323 is for consultation when the referred material requires preparation.

Does 88321 include preparing new slides?

No. The service is the pathologist’s review and report on slides prepared by another laboratory.

When would 88325 be a better fit?

88325 describes a more comprehensive consultation involving review of records and specimens. 88321 is focused on the referred slides.

What documentation supports reporting 88321?

Document the slides reviewed, their outside source, the consultation request, and the pathologist’s findings and conclusions in the report.

Can the original tissue examination report support 88321 by itself?

No. The record should show a separate consultation based on the outside-prepared slides and include the consulting pathologist’s report.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88321PPRRVU2026_Oct_nonQPP.csv, line 11,230 (RVU26D)

Open CMS sourceHow we calculate rates

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