CPT code 88331: Frozen section, first block, one specimen2026 Medicare rate & RVUs in Tennessee

Reports a pathologist’s intraoperative microscopic assessment of frozen tissue from a specimen, providing a rapid diagnosis to guide the surgeon’s immediate decisions.

CMS RVU26DEffective Oct 1, 2026One payment locality307.5K Medicare services in 2024

In Tennessee, Medicare pays $91.50 for 88331 in the office.

$91.50Office (non-facility)
Not available in this settingHospital or facility
−5.9%vs the national office rate ($97.20)

Check a contract rate as a % of Medicare · 88331 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88331 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Tennessee
  2. What 88331 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88331 covers

A pathologist examines frozen tissue during surgery and communicates a rapid microscopic interpretation to the surgeon, often to assess a margin or clarify the nature of tissue before the operation proceeds. The service is performed in connection with an operation, with pathology staff preparing the frozen tissue and slides and the pathologist providing the interpretation. The assessment is for one specimen’s first tissue block.

Report this code for the first frozen-section block; report each additional block for that specimen with 88332. Documentation should identify the specimen and block, describe the intraoperative examination, and record the interpretation communicated to the surgical team. CMS recognizes separately priced professional and technical components: modifier 26 identifies the interpretation, modifier TC identifies the equipment and staff work, and an unmodified claim represents the global service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Tennessee compares for 88331

Across 109 of 109 payment localities, the office rate for 88331 runs from $88.61 in Arkansas to $126.39 in San Benito County, CA. Tennessee pays $91.50. The RVUs are the same everywhere; the geographic indexes change the dollars.

88331 in Tennessee vs other payment areas
  1. Tennessee · this page$91.50
  2. Los Angeles, CA · California$108.96+$17.46
  3. Washington, DC area · District of Columbia$109.63+$18.13
  4. Miami, FL · Florida$101.08+$9.58
  5. Chicago, IL · Illinois$99.05+$7.55
  6. Manhattan, NY · New York$109.57+$18.07
  7. Alaska · Alaska$119.85+$28.35

Other areas in Tennessee first, then benchmark localities. Bars start at $0.

Every other payment area

88331 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$89.58—
ArkansasArkansas$88.61—
ArizonaArizona$95.27—
Bakersfield, CACalifornia$103.06—
Chico, CACalifornia$102.91—
El Centro, CACalifornia$102.91—
Fresno, CACalifornia$102.91—
Hanford, CACalifornia$102.91—

88331 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$88.61

$119.85

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88331 office rate range by state
State / territoryOffice rate rangeLocalities
AK$119.851
AL$89.581
AR$88.611
AZ$95.271
CA$102.91–$126.3929
CO$101.121
CT$102.611
DC$109.631
DE$96.601
FL$95.17–$101.083
GA$91.18–$98.432
GU$104.651
HI$104.651
IA$91.711
ID$92.071
IL$92.76–$99.794
IN$92.491
KS$91.181
KY$90.731
LA$90.55–$93.942
MA$100.66–$109.822
MD$98.19–$109.633
ME$92.22–$96.312
MI$92.33–$95.872
MN$98.161
MO$89.24–$94.443
MS$88.951
MT$97.191
NC$92.991
ND$96.601
NE$92.151
NH$99.431
NJ$104.13–$108.902
NM$92.631
NV$97.091
NY$94.03–$111.395
OH$92.211
OK$90.831
OR$96.67–$103.942
PA$92.43–$100.442
PR$97.811
RI$99.721
SC$92.681
SD$96.531
TN$91.501
TX$91.96–$100.498
UT$93.651
VA$95.93–$109.632
VI$97.811
VT$96.131
WA$100.51–$111.992
WI$94.091
WV$90.101
WY$96.941

See 88331 in every payment locality

How the 88331 rate is calculated

Each of 88331’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88331

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.16

1.16 RVUs× 1.000 GPCI

Practice expense1.72

1.72 RVUs× 1.000 GPCI

Malpractice0.03

0.03 RVUs× 1.000 GPCI

Adjusted RVUs

2.9100

Conversion factor

$33.4009

Medicare rate

$97.20

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Tennessee inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,236

Code
88331
Physician work
1.16
Practice expense
1.72
Malpractice
0.03

GPCI2026.csv

95

Locality
Tennessee
Physician work
1.000
Practice expense
0.909
Malpractice
0.537
Office calculation for 88331 in Tennessee
ComponentRVULocality factorAdjusted
Physician work1.16× 1.0001.1600
Practice expense1.72× 0.9091.5635
Malpractice0.03× 0.5370.0161
Total RVUs2.7396
Conversion factor× 33.4009

Office rate, Tennessee$91.50

Office: (1.16 × 1 + 1.72 × 0.909 + 0.03 × 0.537) × $33.4009 = $91.50

Open 88331 in the RVU calculator

Payment rules and modifiers for 88331

The CMS indicators that decide how 88331 is paid alongside other services.

CMS payment indicators · 88331

Frozen section, first block, one specimen

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

88331 without 26 · national office

$97.20

Frozen section, first block, one specimen

88331-26 · Professional component

$57.78

Pays only the interpretation and report.

When to use modifier 26

How 88331 has changed in Tennessee

88331 · Office / nonfacility

$91.50

Effective 2026-10-01

The base rate is $0.31 higher than on 2025-10-01, moving from $91.19 to $91.50 (0.3%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $91.19changed to$91.50

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.19 changed to 1.16
    • Practice expense RVU 1.80 changed to 1.72
    • Practice expense GPCI 0.896 changed to 0.909
    • Malpractice GPCI 0.544 changed to 0.537

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $94.14changed to$91.19

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 1.81 changed to 1.80

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $92.60changed to$94.14

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $95.69changed to$92.60

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense GPCI 0.894 changed to 0.896
    • Malpractice GPCI 0.518 changed to 0.544
  5. January 1, 2023

    RVU23A

    $96.33changed to$95.69

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 1.77 changed to 1.81
    • Practice expense GPCI 0.892 changed to 0.894
    • Malpractice GPCI 0.492 changed to 0.518

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $97.44changed to$96.33

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 1.78 changed to 1.77

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $94.00changed to$97.44

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 1.56 changed to 1.78
    • Practice expense GPCI 0.897 changed to 0.892
    • Malpractice GPCI 0.509 changed to 0.492

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $93.00changed to$94.00

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 1.52 changed to 1.56
    • Malpractice RVU 0.04 changed to 0.03
    • Practice expense GPCI 0.901 changed to 0.897
    • Malpractice GPCI 0.526 changed to 0.509

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $93.55changed to$93.00

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 1.54 changed to 1.52

    Held through RVU19B, RVU19C, RVU19D.

  10. April 1, 2018

    RVU18B

    No ratechanged to$93.55

    Held through RVU18C, RVU18D.

  11. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$91.50Not available in this settingRVU26D
2026-07-01$91.50Not available in this settingRVU26C
2026-04-01$91.50Not available in this settingRVU26B
2026-01-01$91.50Not available in this settingRVU26A
2025-10-01$91.19Not available in this settingRVU25D
2025-07-01$91.19Not available in this settingRVU25C
2025-04-01$91.19Not available in this settingRVU25B
2025-01-01$91.19Not available in this settingRVU25A
2024-10-01$94.14Not available in this settingRVU24D
2024-07-01$94.14Not available in this settingRVU24C
2024-04-01$94.14Not available in this settingRVU24B
2024-03-09$94.14Not available in this settingRVU24AR
2024-01-01$92.60Not available in this settingRVU24A
2023-10-01$95.69Not available in this settingRVU23D
2023-07-01$95.69Not available in this settingRVU23C
2023-04-01$95.69Not available in this settingRVU23B
2023-01-01$95.69Not available in this settingRVU23A
2022-10-01$96.33Not available in this settingRVU22D
2022-07-01$96.33Not available in this settingRVU22C
2022-04-01$96.33Not available in this settingRVU22B
2022-01-01$96.33Not available in this settingRVU22A
2021-10-01$97.44Not available in this settingRVU21D
2021-07-01$97.44Not available in this settingRVU21C
2021-04-01$97.44Not available in this settingRVU21B
2021-01-01$97.44Not available in this settingRVU21A
2020-10-01$94.00Not available in this settingRVU20D
2020-07-01$94.00Not available in this settingRVU20C
2020-04-01$94.00Not available in this settingRVU20B
2020-01-01$94.00Not available in this settingRVU20A
2019-10-01$93.00Not available in this settingRVU19D
2019-07-01$93.00Not available in this settingRVU19C
2019-04-01$93.00Not available in this settingRVU19B
2019-01-01$93.00Not available in this settingRVU19A
2018-10-01$93.55Not available in this settingRVU18D
2018-07-01$93.55Not available in this settingRVU18C
2018-04-01$93.55Not available in this settingRVU18B
2018-01-01Rate data unavailableNot available in this settingRVU18AR1
2017-10-01Rate data unavailableNot available in this settingRVU17D
2017-07-01Rate data unavailableNot available in this settingRVU17C
2017-04-01Rate data unavailableNot available in this settingRVU17B
2017-01-01Rate data unavailableNot available in this settingRVU17A
2016-10-01Rate data unavailableNot available in this settingRVU16D
2016-07-01Rate data unavailableNot available in this settingRVU16C
2016-04-01Rate data unavailableNot available in this settingRVU16B
2016-01-01Rate data unavailableNot available in this settingRVU16A
2015-10-01Rate data unavailableNot available in this settingRVU15D
2015-07-01Rate data unavailableNot available in this settingRVU15C
2015-04-01Rate data unavailableNot available in this settingRVU15B
2015-01-01Rate data unavailableNot available in this settingRVU15A
2014-10-01Rate data unavailableNot available in this settingRVU14D
2014-07-01Rate data unavailableNot available in this settingRVU14C
2014-04-01Rate data unavailableNot available in this settingRVU14B
2014-01-01Rate data unavailableNot available in this settingRVU14A
2013-10-01Rate data unavailableNot available in this settingRVU13D
2013-07-01Rate data unavailableNot available in this settingRVU13C
2013-04-01Rate data unavailableNot available in this settingRVU13B
2013-01-01Rate data unavailableNot available in this settingRVU13AR

Price 88331 for an earlier date of service

Where the Tennessee rate applies

Tennessee is a Medicare payment area, not a city. Our Census mapping connects it to 504 cities and communities in Tennessee. Some span more than one payment area; confirm with the service ZIP.

  • Adams
  • Adamsville
  • Alamo
  • Alcoa
  • Alexandria
  • Algood
  • Allardt
  • Altamont

Browse all communities in Tennessee

88331 billing questions

When is 88331 chosen instead of 88329?

Use 88331 when the intraoperative consultation includes microscopic examination of frozen tissue. Code 88329 is for an intraoperative pathology consultation based on gross examination.

How are additional frozen-section blocks reported?

Report 88331 for the first block for a specimen and 88332 for each additional block. The record should support the blocks actually examined.

Can 88331 be billed with modifier 26 or TC?

Yes. Modifier 26 represents the pathologist’s interpretation, while TC represents the technical work, including equipment and staff. Without either modifier, the claim represents the global service.

How does 88331 differ from 88333?

88331 reports microscopic examination of frozen tissue. Code 88333 is for an intraoperative cytologic examination, such as a touch preparation or squash preparation.

Can a definitive surgical pathology examination also be reported?

A definitive examination of the specimen may follow the intraoperative frozen-section assessment. Select the surgical pathology code, such as 88305, based on the specimen and the work performed for that examination.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88331PPRRVU2026_Oct_nonQPP.csv, line 11,236 (RVU26D)
Geographic factors for TennesseeGPCI2026.csv, line 95 (RVU26D)

Open CMS sourceHow we calculate rates

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