CPT code 88333: Surgical cytology, initial specimen2026 Medicare rate & RVUs in Delaware

A pathologist rapidly evaluates an initial intraoperative tissue specimen using a cytologic preparation to guide an immediate surgical decision.

CMS RVU26DEffective Oct 1, 2026One payment locality56.2K Medicare services in 2024

In Delaware, Medicare pays $87.70 for 88333 in the office.

$87.70Office (non-facility)
Not available in this settingHospital or facility
−0.5%vs the national office rate ($88.18)

Check a contract rate as a % of Medicare · 88333 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88333 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Delaware
  2. What 88333 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88333 covers

During surgery, a pathologist examines a rapid cytologic preparation of tissue submitted by the operating team. Common preparations include a touch prep or squash prep. The pathologist interprets the cells and communicates a preliminary finding while the patient is still in the operating room, helping the surgeon make an immediate decision. This service is typically performed in a hospital or other surgical setting where the pathologist can provide an intraoperative consultation.

Report 88333 for the initial cytologic specimen examined; use 88334 for each additional cytologic specimen. The record should identify the specimen, document the cytologic method and interpretation, and support that the evaluation occurred during surgery. Modifier 26 represents the professional interpretation, while modifier TC represents the technical work, equipment, and staff. Reporting the code without either modifier represents the global service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Delaware compares for 88333

Across 109 of 109 payment localities, the office rate for 88333 runs from $80.91 in Arkansas to $113.27 in San Benito County, CA. Delaware pays $87.70. The RVUs are the same everywhere; the geographic indexes change the dollars.

88333 in Delaware vs other payment areas
  1. Delaware · this page$87.70
  2. Los Angeles, CA · California$98.25+$10.55
  3. Washington, DC area · District of Columbia$98.96+$11.26
  4. Miami, FL · Florida$91.68+$3.98
  5. Chicago, IL · Illinois$89.99+$2.29
  6. Manhattan, NY · New York$99.06+$11.36
  7. Alaska · Alaska$110.39+$22.69

Other areas in Delaware first, then benchmark localities. Bars start at $0.

Every other payment area

88333 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$81.73—
ArkansasArkansas$80.91—
ArizonaArizona$86.54—
Bakersfield, CACalifornia$93.15—
Chico, CACalifornia$93.00—
El Centro, CACalifornia$93.00—
Fresno, CACalifornia$93.00—
Hanford, CACalifornia$93.00—

88333 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$80.91

$110.39

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88333 office rate range by state
State / territoryOffice rate rangeLocalities
AK$110.391
AL$81.731
AR$80.911
AZ$86.541
CA$93.00–$113.2729
CO$91.511
CT$92.871
DC$98.961
DE$87.701
FL$86.57–$91.683
GA$83.18–$89.272
GU$94.351
HI$94.351
IA$83.491
ID$83.801
IL$84.56–$90.524
IN$84.151
KS$83.061
KY$82.751
LA$82.61–$85.482
MA$91.15–$99.002
MD$89.06–$98.963
ME$83.95–$87.382
MI$84.12–$87.182
MN$88.871
MO$81.51–$85.873
MS$81.231
MT$88.181
NC$84.591
ND$87.581
NE$83.851
NH$90.031
NJ$94.26–$98.402
NM$84.391
NV$88.061
NY$85.48–$100.635
OH$84.001
OK$82.811
OR$87.69–$93.892
PA$84.18–$91.052
PR$88.691
RI$90.401
SC$84.371
SD$87.511
TN$83.341
TX$83.78–$90.938
UT$85.191
VA$87.07–$98.962
VI$88.691
VT$87.201
WA$91.00–$100.872
WI$85.461
WV$82.311
WY$87.921

See 88333 in every payment locality

How the 88333 rate is calculated

Each of 88333’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88333

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.17

1.17 RVUs× 1.000 GPCI

Practice expense1.44

1.44 RVUs× 1.000 GPCI

Malpractice0.03

0.03 RVUs× 1.000 GPCI

Adjusted RVUs

2.6400

Conversion factor

$33.4009

Medicare rate

$88.18

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Delaware inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,242

Code
88333
Physician work
1.17
Practice expense
1.44
Malpractice
0.03

GPCI2026.csv

40

Locality
Delaware
Physician work
1.005
Practice expense
0.988
Malpractice
0.899
Office calculation for 88333 in Delaware
ComponentRVULocality factorAdjusted
Physician work1.17× 1.0051.1758
Practice expense1.44× 0.9881.4227
Malpractice0.03× 0.8990.0270
Total RVUs2.6255
Conversion factor× 33.4009

Office rate, Delaware$87.70

Office: (1.17 × 1.005 + 1.44 × 0.988 + 0.03 × 0.899) × $33.4009 = $87.70

Open 88333 in the RVU calculator

Payment rules and modifiers for 88333

The CMS indicators that decide how 88333 is paid alongside other services.

CMS payment indicators · 88333

Surgical cytology, initial specimen

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

88333 without 26 · national office

$88.18

Surgical cytology, initial specimen

88333-26 · Professional component

$57.45

Pays only the interpretation and report.

When to use modifier 26

How 88333 has changed in Delaware

88333 · Office / nonfacility

$87.70

Effective 2026-10-01

The base rate is $0.52 lower than on 2025-10-01, moving from $88.22 to $87.70 (0.6%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $88.22changed to$87.70

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.20 changed to 1.17
    • Practice expense RVU 1.50 changed to 1.44
    • Work GPCI 1.009 changed to 1.005
    • Practice expense GPCI 0.992 changed to 0.988
    • Malpractice GPCI 0.949 changed to 0.899

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $91.11changed to$88.22

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 1.51 changed to 1.50

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $89.63changed to$91.11

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $94.11changed to$89.63

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 1.53 changed to 1.51
    • Work GPCI 1.007 changed to 1.009
    • Practice expense GPCI 1.007 changed to 0.992
    • Malpractice GPCI 0.938 changed to 0.949
  5. January 1, 2023

    RVU23A

    $95.75changed to$94.11

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 1.50 changed to 1.53
    • Work GPCI 1.005 changed to 1.007
    • Practice expense GPCI 1.022 changed to 1.007
    • Malpractice GPCI 0.927 changed to 0.938

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $97.61changed to$95.75

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 1.53 changed to 1.50

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $93.31changed to$97.61

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 1.32 changed to 1.53
    • Work GPCI 1.006 changed to 1.005
    • Practice expense GPCI 1.021 changed to 1.022
    • Malpractice GPCI 1.023 changed to 0.927

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $92.54changed to$93.31

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 1.29 changed to 1.32
    • Malpractice RVU 0.04 changed to 0.03
    • Work GPCI 1.007 changed to 1.006
    • Practice expense GPCI 1.019 changed to 1.021
    • Malpractice GPCI 1.119 changed to 1.023

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $93.17changed to$92.54

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 1.31 changed to 1.29

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $97.31changed to$93.17

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 1.42 changed to 1.31
    • Work GPCI 1.010 changed to 1.007
    • Practice expense GPCI 1.025 changed to 1.019
    • Malpractice GPCI 1.101 changed to 1.119

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $104.09changed to$97.31

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 1.60 changed to 1.42
    • Work GPCI 1.012 changed to 1.010
    • Practice expense GPCI 1.031 changed to 1.025
    • Malpractice GPCI 1.083 changed to 1.101

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $112.23changed to$104.09

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 1.82 changed to 1.60
    • Malpractice RVU 0.03 changed to 0.04

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $111.67changed to$112.23

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $107.17changed to$111.67

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 1.67 changed to 1.82
    • Malpractice RVU 0.05 changed to 0.03
    • Practice expense GPCI 1.038 changed to 1.031
    • Malpractice GPCI 0.878 changed to 1.083

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $107.82changed to$107.17

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 1.84 changed to 1.67
    • Practice expense GPCI 1.044 changed to 1.038
    • Malpractice GPCI 0.672 changed to 0.878

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $107.82

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$87.70Not available in this settingRVU26D
2026-07-01$87.70Not available in this settingRVU26C
2026-04-01$87.70Not available in this settingRVU26B
2026-01-01$87.70Not available in this settingRVU26A
2025-10-01$88.22Not available in this settingRVU25D
2025-07-01$88.22Not available in this settingRVU25C
2025-04-01$88.22Not available in this settingRVU25B
2025-01-01$88.22Not available in this settingRVU25A
2024-10-01$91.11Not available in this settingRVU24D
2024-07-01$91.11Not available in this settingRVU24C
2024-04-01$91.11Not available in this settingRVU24B
2024-03-09$91.11Not available in this settingRVU24AR
2024-01-01$89.63Not available in this settingRVU24A
2023-10-01$94.11Not available in this settingRVU23D
2023-07-01$94.11Not available in this settingRVU23C
2023-04-01$94.11Not available in this settingRVU23B
2023-01-01$94.11Not available in this settingRVU23A
2022-10-01$95.75Not available in this settingRVU22D
2022-07-01$95.75Not available in this settingRVU22C
2022-04-01$95.75Not available in this settingRVU22B
2022-01-01$95.75Not available in this settingRVU22A
2021-10-01$97.61Not available in this settingRVU21D
2021-07-01$97.61Not available in this settingRVU21C
2021-04-01$97.61Not available in this settingRVU21B
2021-01-01$97.61Not available in this settingRVU21A
2020-10-01$93.31Not available in this settingRVU20D
2020-07-01$93.31Not available in this settingRVU20C
2020-04-01$93.31Not available in this settingRVU20B
2020-01-01$93.31Not available in this settingRVU20A
2019-10-01$92.54Not available in this settingRVU19D
2019-07-01$92.54Not available in this settingRVU19C
2019-04-01$92.54Not available in this settingRVU19B
2019-01-01$92.54Not available in this settingRVU19A
2018-10-01$93.17Not available in this settingRVU18D
2018-07-01$93.17Not available in this settingRVU18C
2018-04-01$93.17Not available in this settingRVU18B
2018-01-01$93.17Not available in this settingRVU18AR1
2017-10-01$97.31Not available in this settingRVU17D
2017-07-01$97.31Not available in this settingRVU17C
2017-04-01$97.31Not available in this settingRVU17B
2017-01-01$97.31Not available in this settingRVU17A
2016-10-01$104.09Not available in this settingRVU16D
2016-07-01$104.09Not available in this settingRVU16C
2016-04-01$104.09Not available in this settingRVU16B
2016-01-01$104.09Not available in this settingRVU16A
2015-10-01$112.23Not available in this settingRVU15D
2015-07-01$112.23Not available in this settingRVU15C
2015-04-01$111.67Not available in this settingRVU15B
2015-01-01$111.67Not available in this settingRVU15A
2014-10-01$107.17Not available in this settingRVU14D
2014-07-01$107.17Not available in this settingRVU14C
2014-04-01$107.17Not available in this settingRVU14B
2014-01-01$107.17Not available in this settingRVU14A
2013-10-01$107.82Not available in this settingRVU13D
2013-07-01$107.82Not available in this settingRVU13C
2013-04-01$107.82Not available in this settingRVU13B
2013-01-01$107.82Not available in this settingRVU13AR

Price 88333 for an earlier date of service

Where the Delaware rate applies

Delaware is a Medicare payment area, not a city. Our Census mapping connects it to 79 cities and communities in Delaware. Some span more than one payment area; confirm with the service ZIP.

  • Arden
  • Ardencroft
  • Ardentown
  • Bear
  • Bellefonte
  • Bethany Beach
  • Bethel
  • Blades

Browse all communities in Delaware

88333 billing questions

When should 88333 be chosen instead of 88331?

Use 88333 for an intraoperative cytologic preparation, such as a touch prep or squash prep. Use 88331 when the pathologist examines a frozen tissue section.

How is another cytologic specimen reported?

88333 covers the initial cytologic specimen. Report 88334 for each additional cytologic specimen examined during the intraoperative consultation.

Can the professional and technical portions be billed separately?

Yes. Modifier 26 identifies the pathologist’s interpretation, and modifier TC identifies the technical portion. Without either modifier, 88333 represents the global service.

What documentation supports 88333?

Document the specimen examined, the cytologic preparation and findings, and the intraoperative communication to the surgical team. The record should establish that the evaluation took place during surgery.

Is 88333 for gross examination alone?

No. 88333 involves cytologic evaluation of a preparation. An intraoperative consultation limited to gross examination is represented by 88329.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88333PPRRVU2026_Oct_nonQPP.csv, line 11,242 (RVU26D)
Geographic factors for DelawareGPCI2026.csv, line 40 (RVU26D)

Open CMS sourceHow we calculate rates

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