CPT code 88355: Muscle analysis, skeletal muscle2026 Medicare rate & RVUs in Queens, NY
Reports quantitative morphometric measurement of skeletal muscle biopsy tissue, typically when evaluating suspected myopathic or neurogenic disease beyond routine histologic examination.
In Queens, NY, Medicare pays $158.98 for 88355 in the office.
Check a contract rate as a % of Medicare · 88355 nationwide
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 11 sections
What 88355 covers
A pathology laboratory performs quantitative morphometric assessment of skeletal muscle tissue, commonly from a biopsy obtained during evaluation of suspected myopathy, muscular dystrophy, or neurogenic muscle change. The analysis measures histologic muscle-fiber features; a pathologist interprets the findings in the context of the tissue and clinical question. It may be performed in a hospital laboratory or an independent pathology laboratory.
Report 88355 when skeletal muscle morphometric analysis is performed in addition to routine tissue examination, not for routine microscopic review alone. The report should identify the specimen and document the quantitative analysis and findings. CMS recognizes a professional component for interpretation and a technical component for the equipment and staff performing the test. Report modifier 26 for the professional component, modifier TC for the technical component, or neither modifier for the global service.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
How Queens, NY compares for 88355
Across 109 of 109 payment localities, the office rate for 88355 runs from $128.64 in Arkansas to $181.42 in San Benito County, CA. Queens, NY pays $158.98. The RVUs are the same everywhere; the geographic indexes change the dollars.
- Queens, NY · this page$158.98
- Manhattan, NY · New York$157.54−$1.44
- NYC suburbs and Long Island, NY · New York$159.95+$0.97
- Poughkeepsie and northern NYC suburbs, NY · New York$150.72−$8.26
- Rest of New York · New York$136.03−$22.95
- Los Angeles, CA · California$156.90−$2.08
- Washington, DC area · District of Columbia$157.73−$1.25
Other areas in New York first, then benchmark localities. Bars start at $0.
Every other payment area
| Payment locality | Office | Facility |
|---|---|---|
| Miami, FLFlorida | $145.06 | — |
| Chicago, ILIllinois | $142.40 | — |
| AlaskaAlaska | $175.04 | — |
| AlabamaAlabama | $129.95 | — |
| ArkansasArkansas | $128.64 | — |
| ArizonaArizona | $137.69 | — |
| Bakersfield, CACalifornia | $148.63 | — |
| Chico, CACalifornia | $148.44 | — |
| El Centro, CACalifornia | $148.45 | — |
| Fresno, CACalifornia | $148.44 | — |
| Hanford, CACalifornia | $148.44 | — |
| Madera, CACalifornia | $148.44 | — |
| Merced, CACalifornia | $148.44 | — |
| Modesto, CACalifornia | $148.44 | — |
| Napa, CACalifornia | $168.75 | — |
| Oxnard, CACalifornia | $156.00 | — |
| Redding, CACalifornia | $148.44 | — |
| Rest of CaliforniaCalifornia | $148.44 | — |
| Riverside, CACalifornia | $148.82 | — |
| Sacramento, CACalifornia | $154.89 | — |
| Salinas, CACalifornia | $154.27 | — |
| San Diego, CACalifornia | $157.14 | — |
| Marin County, CACalifornia | $177.91 | — |
| San Francisco, CACalifornia | $177.87 | — |
| San Benito County, CACalifornia | $181.42 | — |
| Santa Clara County, CACalifornia | $181.28 | — |
| San Luis Obispo, CACalifornia | $151.84 | — |
| Santa Cruz, CACalifornia | $158.10 | — |
| Santa Maria, CACalifornia | $154.64 | — |
| Santa Rosa, CACalifornia | $159.67 | — |
| Stockton, CACalifornia | $148.44 | — |
| Vallejo, CACalifornia | $168.70 | — |
| Visalia, CACalifornia | $148.44 | — |
| Yuba City, CACalifornia | $148.44 | — |
| ColoradoColorado | $145.85 | — |
| ConnecticutConnecticut | $147.79 | — |
| DelawareDelaware | $139.53 | — |
| Fort Lauderdale, FLFlorida | $142.12 | — |
| Rest of FloridaFlorida | $137.30 | — |
| Atlanta, GAGeorgia | $141.93 | — |
| Rest of GeorgiaGeorgia | $131.93 | — |
| Hawaii, Guam, HIHawaii | $150.71 | — |
| IowaIowa | $132.95 | — |
| IdahoIdaho | $133.42 | — |
| East St. Louis, ILIllinois | $134.97 | — |
| Rest of IllinoisIllinois | $133.96 | — |
| Suburban Chicago, ILIllinois | $143.62 | — |
| IndianaIndiana | $133.99 | — |
| KansasKansas | $132.19 | — |
| KentuckyKentucky | $131.41 | — |
| New Orleans, LALouisiana | $135.75 | — |
| Rest of LouisianaLouisiana | $131.14 | — |
| Metropolitan Boston, MAMassachusetts | $158.00 | — |
| Rest of MassachusettsMassachusetts | $145.24 | — |
| Baltimore area, MDMaryland | $147.26 | — |
| Rest of MarylandMaryland | $141.75 | — |
| Rest of MaineMaine | $133.57 | — |
| Southern Maine, MEMaine | $139.20 | — |
| Detroit, MIMichigan | $138.20 | — |
| Rest of MichiganMichigan | $133.53 | — |
| MinnesotaMinnesota | $141.87 | — |
| Metropolitan Kansas City, MOMissouri | $135.43 | — |
| Metropolitan St. Louis, MOMissouri | $136.49 | — |
| Rest of MissouriMissouri | $129.33 | — |
| MississippiMississippi | $129.02 | — |
| MontanaMontana | $140.28 | — |
| North CarolinaNorth Carolina | $134.62 | — |
| North DakotaNorth Dakota | $139.69 | — |
| NebraskaNebraska | $133.57 | — |
| New HampshireNew Hampshire | $143.40 | — |
| Northern New JerseyNew Jersey | $156.81 | — |
| Rest of New JerseyNew Jersey | $150.07 | — |
| New MexicoNew Mexico | $133.91 | — |
| NevadaNevada | $140.20 | — |
| OhioOhio | $133.40 | — |
| OklahomaOklahoma | $131.59 | — |
| Portland, OROregon | $149.78 | — |
| Rest of OregonOregon | $139.67 | — |
| Metropolitan Philadelphia, PAPennsylvania | $144.80 | — |
| Rest of PennsylvaniaPennsylvania | $133.74 | — |
| Puerto RicoPuerto Rico | $141.14 | — |
| Rhode IslandRhode Island | $143.93 | — |
| South CarolinaSouth Carolina | $134.12 | — |
| South DakotaSouth Dakota | $139.62 | — |
| TennesseeTennessee | $132.62 | — |
| Austin, TXTexas | $144.88 | — |
| Beaumont, TXTexas | $133.09 | — |
| Brazoria, TXTexas | $139.83 | — |
| Dallas, TXTexas | $140.37 | — |
| Fort Worth, TXTexas | $139.59 | — |
| Galveston, TXTexas | $140.04 | — |
| Houston, TXTexas | $140.59 | — |
| Rest of TexasTexas | $136.15 | — |
| UtahUtah | $135.43 | — |
| VirginiaVirginia | $138.64 | — |
| Virgin Islands, VIUnited States Virgin Islands | $141.14 | — |
| VermontVermont | $139.00 | — |
| Rest of WashingtonWashington | $145.02 | — |
| King County, WAWashington | $161.08 | — |
| WisconsinWisconsin | $136.27 | — |
| West VirginiaWest Virginia | $130.35 | — |
| WyomingWyoming | $140.02 | — |
88355 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$128.64
$175.04
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $175.04 | 1 |
| AL | $129.95 | 1 |
| AR | $128.64 | 1 |
| AZ | $137.69 | 1 |
| CA | $148.44–$181.42 | 29 |
| CO | $145.85 | 1 |
| CT | $147.79 | 1 |
| DC | $157.73 | 1 |
| DE | $139.53 | 1 |
| FL | $137.30–$145.06 | 3 |
| GA | $131.93–$141.93 | 2 |
| GU | $150.71 | 1 |
| HI | $150.71 | 1 |
| IA | $132.95 | 1 |
| ID | $133.42 | 1 |
| IL | $133.96–$143.62 | 4 |
| IN | $133.99 | 1 |
| KS | $132.19 | 1 |
| KY | $131.41 | 1 |
| LA | $131.14–$135.75 | 2 |
| MA | $145.24–$158.00 | 2 |
| MD | $141.75–$157.73 | 3 |
| ME | $133.57–$139.20 | 2 |
| MI | $133.53–$138.20 | 2 |
| MN | $141.87 | 1 |
| MO | $129.33–$136.49 | 3 |
| MS | $129.02 | 1 |
| MT | $140.28 | 1 |
| NC | $134.62 | 1 |
| ND | $139.69 | 1 |
| NE | $133.57 | 1 |
| NH | $143.40 | 1 |
| NJ | $150.07–$156.81 | 2 |
| NM | $133.91 | 1 |
| NV | $140.20 | 1 |
| NY | $136.03–$159.95 | 5 |
| OH | $133.40 | 1 |
| OK | $131.59 | 1 |
| OR | $139.67–$149.78 | 2 |
| PA | $133.74–$144.80 | 2 |
| PR | $141.14 | 1 |
| RI | $143.93 | 1 |
| SC | $134.12 | 1 |
| SD | $139.62 | 1 |
| TN | $132.62 | 1 |
| TX | $133.09–$144.88 | 8 |
| UT | $135.43 | 1 |
| VA | $138.64–$157.73 | 2 |
| VI | $141.14 | 1 |
| VT | $139.00 | 1 |
| WA | $145.02–$161.08 | 2 |
| WI | $136.27 | 1 |
| WV | $130.35 | 1 |
| WY | $140.02 | 1 |
How the 88355 rate is calculated
Each of 88355’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · 88355
RVUs × geographic indexes × conversion factor
Work1.80
1.80 RVUs× 1.000 GPCI
Practice expense2.37
2.37 RVUs× 1.000 GPCI
Malpractice0.03
0.03 RVUs× 1.000 GPCI
Adjusted RVUs
4.2000
Conversion factor
$33.4009
Medicare rate
$140.28
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
The exact Queens, NY inputs and CMS source lines
PPRRVU2026_Oct_nonQPP.csv
11,266
- Code
- 88355
- Physician work
- 1.80
- Practice expense
- 2.37
- Malpractice
- 0.03
GPCI2026.csv
81
- Locality
- Queens, NY
- Physician work
- 1.064
- Practice expense
- 1.182
- Malpractice
- 1.442
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 1.80 | × 1.064 | 1.9152 |
| Practice expense | 2.37 | × 1.182 | 2.8013 |
| Malpractice | 0.03 | × 1.442 | 0.0433 |
| Total RVUs | 4.7598 | ||
| Conversion factor | × 33.4009 | ||
Office rate, Queens, NY$158.98
Office: (1.8 × 1.064 + 2.37 × 1.182 + 0.03 × 1.442) × $33.4009 = $158.98
Payment rules and modifiers for 88355
The CMS indicators that decide how 88355 is paid alongside other services.
CMS payment indicators · 88355
Muscle analysis, skeletal muscle
| Rule | CMS value | What it means |
|---|---|---|
| Global period | XXX | The global surgery concept doesn’t apply. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 1 | Diagnostic test with separate professional (26) and technical (TC) components. |
What modifiers do to the payment
Modifier 26 · payment effect
With and without the modifier
88355 without 26 · national office
$140.28
Muscle analysis, skeletal muscle
88355-26 · Professional component
$78.49
Pays only the interpretation and report.
How 88355 has changed in Queens, NY
88355 · Office / nonfacility
$158.98
Effective 2026-10-01
The base rate is $1.83 higher than on 2025-10-01, moving from $157.15 to $158.98 (1.2%).
It is unchanged from the immediately preceding available release, effective 2026-07-01.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2026
RVU26A
$157.15changed to$158.98
- Conversion factor 32.3465 changed to 33.4009
- Work RVU 1.85 changed to 1.80
- Practice expense RVU 2.38 changed to 2.37
- Work GPCI 1.065 changed to 1.064
- Practice expense GPCI 1.195 changed to 1.182
- Malpractice GPCI 1.462 changed to 1.442
Held through RVU26B, RVU26C, RVU26D.
January 1, 2025
RVU25A
$143.02changed to$157.15
- Conversion factor 33.2875 changed to 32.3465
- Practice expense RVU 1.91 changed to 2.38
Held through RVU25B, RVU25C, RVU25D.
March 9, 2024
RVU24AR
$140.69changed to$143.02
- Conversion factor 32.7442 changed to 33.2875
Held through RVU24B, RVU24C, RVU24D.
January 1, 2024
RVU24A
$163.49changed to$140.69
- Conversion factor 33.8872 changed to 32.7442
- Practice expense RVU 2.31 changed to 1.91
- Work GPCI 1.061 changed to 1.065
- Practice expense GPCI 1.212 changed to 1.195
- Malpractice GPCI 2.061 changed to 1.462
January 1, 2023
RVU23A
$165.49changed to$163.49
- Conversion factor 34.6062 changed to 33.8872
- Practice expense RVU 2.26 changed to 2.31
- Malpractice RVU 0.02 changed to 0.03
- Work GPCI 1.056 changed to 1.061
- Practice expense GPCI 1.228 changed to 1.212
- Malpractice GPCI 2.661 changed to 2.061
Held through RVU23B, RVU23C, RVU23D.
January 1, 2022
RVU22A
$168.58changed to$165.49
- Conversion factor 34.8931 changed to 34.6062
- Practice expense RVU 2.30 changed to 2.26
Held through RVU22B, RVU22C, RVU22D.
January 1, 2021
RVU21A
$160.16changed to$168.58
- Conversion factor 36.0896 changed to 34.8931
- Practice expense RVU 2.01 changed to 2.30
- Work GPCI 1.054 changed to 1.056
- Practice expense GPCI 1.214 changed to 1.228
- Malpractice GPCI 2.391 changed to 2.661
Held through RVU21B, RVU21C, RVU21D.
January 1, 2020
RVU20A
$152.97changed to$160.16
- Conversion factor 36.0391 changed to 36.0896
- Practice expense RVU 1.88 changed to 2.01
- Work GPCI 1.052 changed to 1.054
- Practice expense GPCI 1.200 changed to 1.214
- Malpractice GPCI 2.121 changed to 2.391
Held through RVU20B, RVU20C, RVU20D.
January 1, 2019
RVU19A
$151.94changed to$152.97
- Conversion factor 35.9996 changed to 36.0391
- Practice expense RVU 1.86 changed to 1.88
Held through RVU19B, RVU19C, RVU19D.
January 1, 2018
RVU18AR1
$164.41changed to$151.94
- Conversion factor 35.8887 changed to 35.9996
- Practice expense RVU 2.16 changed to 1.86
- Malpractice GPCI 2.151 changed to 2.121
Held through RVU18B, RVU18C, RVU18D.
January 1, 2017
RVU17A
$180.71changed to$164.41
- Conversion factor 35.8043 changed to 35.8887
- Practice expense RVU 2.55 changed to 2.16
- Practice expense GPCI 1.199 changed to 1.200
- Malpractice GPCI 2.181 changed to 2.151
Held through RVU17B, RVU17C, RVU17D.
January 1, 2016
RVU16A
$201.97changed to$180.71
- Conversion factor 35.9335 changed to 35.8043
- Practice expense RVU 3.01 changed to 2.55
- Malpractice RVU 0.03 changed to 0.02
Held through RVU16B, RVU16C, RVU16D.
July 1, 2015
RVU15C
$200.96changed to$201.97
- Conversion factor 35.7547 changed to 35.9335
Held through RVU15D.
January 1, 2015
RVU15A
$203.06changed to$200.96
- Conversion factor 35.8228 changed to 35.7547
- Malpractice RVU 0.06 changed to 0.03
- Work GPCI 1.057 changed to 1.052
- Practice expense GPCI 1.197 changed to 1.199
- Malpractice GPCI 1.836 changed to 2.181
Held through RVU15B.
January 1, 2014
RVU14A
$210.56changed to$203.06
- Conversion factor 34.0230 changed to 35.8228
- Practice expense RVU 3.46 changed to 3.01
- Work GPCI 1.062 changed to 1.057
- Practice expense GPCI 1.195 changed to 1.197
- Malpractice GPCI 1.491 changed to 1.836
Held through RVU14B, RVU14C, RVU14D.
January 1, 2013
RVU13AR
Earliest loaded release: $210.56
Held through RVU13B, RVU13C, RVU13D.
| Effective from | Office | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | $158.98 | Not available in this setting | RVU26D |
| 2026-07-01 | $158.98 | Not available in this setting | RVU26C |
| 2026-04-01 | $158.98 | Not available in this setting | RVU26B |
| 2026-01-01 | $158.98 | Not available in this setting | RVU26A |
| 2025-10-01 | $157.15 | Not available in this setting | RVU25D |
| 2025-07-01 | $157.15 | Not available in this setting | RVU25C |
| 2025-04-01 | $157.15 | Not available in this setting | RVU25B |
| 2025-01-01 | $157.15 | Not available in this setting | RVU25A |
| 2024-10-01 | $143.02 | Not available in this setting | RVU24D |
| 2024-07-01 | $143.02 | Not available in this setting | RVU24C |
| 2024-04-01 | $143.02 | Not available in this setting | RVU24B |
| 2024-03-09 | $143.02 | Not available in this setting | RVU24AR |
| 2024-01-01 | $140.69 | Not available in this setting | RVU24A |
| 2023-10-01 | $163.49 | Not available in this setting | RVU23D |
| 2023-07-01 | $163.49 | Not available in this setting | RVU23C |
| 2023-04-01 | $163.49 | Not available in this setting | RVU23B |
| 2023-01-01 | $163.49 | Not available in this setting | RVU23A |
| 2022-10-01 | $165.49 | Not available in this setting | RVU22D |
| 2022-07-01 | $165.49 | Not available in this setting | RVU22C |
| 2022-04-01 | $165.49 | Not available in this setting | RVU22B |
| 2022-01-01 | $165.49 | Not available in this setting | RVU22A |
| 2021-10-01 | $168.58 | Not available in this setting | RVU21D |
| 2021-07-01 | $168.58 | Not available in this setting | RVU21C |
| 2021-04-01 | $168.58 | Not available in this setting | RVU21B |
| 2021-01-01 | $168.58 | Not available in this setting | RVU21A |
| 2020-10-01 | $160.16 | Not available in this setting | RVU20D |
| 2020-07-01 | $160.16 | Not available in this setting | RVU20C |
| 2020-04-01 | $160.16 | Not available in this setting | RVU20B |
| 2020-01-01 | $160.16 | Not available in this setting | RVU20A |
| 2019-10-01 | $152.97 | Not available in this setting | RVU19D |
| 2019-07-01 | $152.97 | Not available in this setting | RVU19C |
| 2019-04-01 | $152.97 | Not available in this setting | RVU19B |
| 2019-01-01 | $152.97 | Not available in this setting | RVU19A |
| 2018-10-01 | $151.94 | Not available in this setting | RVU18D |
| 2018-07-01 | $151.94 | Not available in this setting | RVU18C |
| 2018-04-01 | $151.94 | Not available in this setting | RVU18B |
| 2018-01-01 | $151.94 | Not available in this setting | RVU18AR1 |
| 2017-10-01 | $164.41 | Not available in this setting | RVU17D |
| 2017-07-01 | $164.41 | Not available in this setting | RVU17C |
| 2017-04-01 | $164.41 | Not available in this setting | RVU17B |
| 2017-01-01 | $164.41 | Not available in this setting | RVU17A |
| 2016-10-01 | $180.71 | Not available in this setting | RVU16D |
| 2016-07-01 | $180.71 | Not available in this setting | RVU16C |
| 2016-04-01 | $180.71 | Not available in this setting | RVU16B |
| 2016-01-01 | $180.71 | Not available in this setting | RVU16A |
| 2015-10-01 | $201.97 | Not available in this setting | RVU15D |
| 2015-07-01 | $201.97 | Not available in this setting | RVU15C |
| 2015-04-01 | $200.96 | Not available in this setting | RVU15B |
| 2015-01-01 | $200.96 | Not available in this setting | RVU15A |
| 2014-10-01 | $203.06 | Not available in this setting | RVU14D |
| 2014-07-01 | $203.06 | Not available in this setting | RVU14C |
| 2014-04-01 | $203.06 | Not available in this setting | RVU14B |
| 2014-01-01 | $203.06 | Not available in this setting | RVU14A |
| 2013-10-01 | $210.56 | Not available in this setting | RVU13D |
| 2013-07-01 | $210.56 | Not available in this setting | RVU13C |
| 2013-04-01 | $210.56 | Not available in this setting | RVU13B |
| 2013-01-01 | $210.56 | Not available in this setting | RVU13AR |
Where the Queens, NY rate applies
Queens, NY is a Medicare payment area, not a city. Our Census mapping connects it to 1 cities and communities in New York. Some span more than one payment area; confirm with the service ZIP.
- 88355 in New York · multiple payment areas
88355 billing questions
How is 88355 different from routine muscle biopsy pathology?
Routine microscopic examination evaluates the biopsy for diagnosis. 88355 represents additional quantitative morphometric analysis of skeletal muscle tissue, so the record should support that distinct analysis.
When should 88355 be chosen instead of 88356?
Use 88355 for morphometric analysis of skeletal muscle. 88356 is the related analysis code for nerve tissue.
Can 88355 be reported with the muscle biopsy pathology code?
Both may be reported when the muscle biopsy receives routine surgical pathology examination and a separately performed morphometric analysis. The documentation should show both services.
Which modifiers identify the components?
Modifier 26 identifies the professional interpretation, and modifier TC identifies the technical service. Without either modifier, the claim represents the global service.
What documentation supports 88355?
Document the skeletal muscle specimen, the quantitative morphometric work performed, the findings, and the pathologist's interpretation.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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