CPT code 88363: Tissue preparation, archived tissue, each case2026 Medicare rate & RVUs in South Carolina

Report this service when a pathology laboratory prepares and conveys previously diagnosed, archived tissue for molecular analysis, counted once per case.

CMS RVU26DEffective Oct 1, 2026One payment locality50.5K Medicare services in 2024

In South Carolina, Medicare pays $21.85 for 88363 in the office and $15.06 when it’s performed in a hospital or facility.

$21.85Office (non-facility)
$15.06Hospital or facility
−3.8%vs the national office rate ($22.71)

Check a contract rate as a % of Medicare · 88363 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88363 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in South Carolina
  2. What 88363 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88363 covers

A pathology laboratory prepares tissue that was previously diagnosed and placed in its archive when a clinician later requests molecular testing. The work centers on locating the relevant archived material, preparing the requested tissue, and conveying it to the laboratory that will perform the molecular analysis. A pathologist or pathology laboratory staff may coordinate the preparation as part of diagnostic testing, including when the testing laboratory is separate from the archive holding the tissue.

Report one unit for each qualifying archived case, rather than counting individual slides or tissue pieces as separate cases. The record should identify the archived case, the request for molecular analysis, and the preparation and transfer of tissue. This service covers preparation and conveyance, not the molecular assay itself; code the assay separately when it is performed and separately reportable. CMS assigns this code work, practice-expense, and malpractice relative values, with practice-expense inputs that differ between office and facility settings.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Carolina compares for 88363

Across 109 of 109 payment localities, the office rate for 88363 runs from $20.98 in Arkansas to $29.08 in Alaska. South Carolina pays $21.85. The RVUs are the same everywhere; the geographic indexes change the dollars.

88363 in South Carolina vs other payment areas
  1. South Carolina · this page$21.85
  2. Los Angeles, CA · California$24.81+$2.96
  3. Washington, DC area · District of Columbia$25.22+$3.37
  4. Miami, FL · Florida$24.14+$2.29
  5. Chicago, IL · Illinois$23.71+$1.86
  6. Manhattan, NY · New York$25.50+$3.65
  7. Alaska · Alaska$29.08+$7.23

Other areas in South Carolina first, then benchmark localities. Bars start at $0.

Every other payment area

88363 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$21.17$14.74
ArkansasArkansas$20.98$14.66
ArizonaArizona$22.31$15.19
Bakersfield, CACalifornia$23.64$15.59
Chico, CACalifornia$23.57$15.52
El Centro, CACalifornia$23.57$15.52
Fresno, CACalifornia$23.57$15.52
Hanford, CACalifornia$23.57$15.52

88363 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$20.98

$29.08

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88363 office rate range by state
State / territoryOffice rate rangeLocalities
AK$29.081
AL$21.171
AR$20.981
AZ$22.311
CA$23.57–$28.1529
CO$23.351
CT$23.861
DC$25.221
DE$22.591
FL$22.61–$24.143
GA$21.76–$23.042
GU$23.801
HI$23.801
IA$21.461
ID$21.561
IL$22.22–$23.714
IN$21.641
KS$21.421
KY$21.541
LA$21.53–$22.212
MA$23.30–$25.082
MD$22.90–$25.223
ME$21.66–$22.382
MI$21.93–$22.822
MN$22.531
MO$21.31–$22.233
MS$21.151
MT$22.711
NC$21.801
ND$22.321
NE$21.531
NH$23.041
NJ$24.18–$25.122
NM$22.021
NV$22.611
NY$22.01–$25.955
OH$21.851
OK$21.491
OR$22.47–$23.852
PA$21.85–$23.472
PR$22.811
RI$23.201
SC$21.851
SD$22.271
TN$21.491
TX$21.76–$23.248
UT$22.041
VA$22.35–$25.222
VI$22.811
VT$22.281
WA$23.24–$25.472
WI$21.831
WV$21.691
WY$22.541

See 88363 in every payment locality

How the 88363 rate is calculated

Each of 88363’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88363

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.36

0.36 RVUs× 1.000 GPCI

Practice expense0.30

0.30 RVUs× 1.000 GPCI

Malpractice0.02

0.02 RVUs× 1.000 GPCI

Adjusted RVUs

0.6800

Conversion factor

$33.4009

Medicare rate

$22.71

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact South Carolina inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,284

Code
88363
Physician work
0.36
Practice expense
0.30
Malpractice
0.02

GPCI2026.csv

93

Locality
South Carolina
Physician work
1.000
Practice expense
0.924
Malpractice
0.850
Office calculation for 88363 in South Carolina
ComponentRVULocality factorAdjusted
Physician work0.36× 1.0000.3600
Practice expense0.30× 0.9240.2772
Malpractice0.02× 0.8500.0170
Total RVUs0.6542
Conversion factor× 33.4009

Office rate, South Carolina$21.85

Office: (0.36 × 1 + 0.3 × 0.924 + 0.02 × 0.85) × $33.4009 = $21.85

Facility: (0.36 × 1 + 0.08 × 0.924 + 0.02 × 0.85) × $33.4009 = $15.06

Open 88363 in the RVU calculator

Payment rules and modifiers for 88363

88363 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · 88363

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

$22.71

Non-facility (office)
$22.71
Facility
$15.36

Higher because the practice carries its own overhead.

How 88363 has changed in South Carolina

88363 · Office / nonfacility

$21.85

Effective 2026-10-01

The base rate is $0.20 higher than on 2025-10-01, moving from $21.65 to $21.85 (0.9%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $21.65changed to$21.85

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.37 changed to 0.36
    • Practice expense RVU 0.31 changed to 0.30
    • Practice expense GPCI 0.913 changed to 0.924
    • Malpractice GPCI 0.817 changed to 0.850

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $21.98changed to$21.65

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 0.30 changed to 0.31

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $21.62changed to$21.98

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $21.97changed to$21.62

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 0.29 changed to 0.30
    • Practice expense GPCI 0.908 changed to 0.913
    • Malpractice GPCI 0.756 changed to 0.817
  5. January 1, 2023

    RVU23A

    $22.04changed to$21.97

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 0.28 changed to 0.29
    • Practice expense GPCI 0.903 changed to 0.908
    • Malpractice GPCI 0.695 changed to 0.756

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $22.22changed to$22.04

    • Conversion factor 34.8931 changed to 34.6062

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $22.97changed to$22.22

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense GPCI 0.907 changed to 0.903
    • Malpractice GPCI 0.624 changed to 0.695

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $22.94changed to$22.97

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense GPCI 0.912 changed to 0.907
    • Malpractice GPCI 0.553 changed to 0.624

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $23.24changed to$22.94

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 0.29 changed to 0.28

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $22.90changed to$23.24

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 0.28 changed to 0.29
    • Malpractice GPCI 0.634 changed to 0.553

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $22.25changed to$22.90

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 0.26 changed to 0.28
    • Malpractice GPCI 0.715 changed to 0.634

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $22.00changed to$22.25

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 0.25 changed to 0.26

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $21.89changed to$22.00

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $21.10changed to$21.89

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 0.22 changed to 0.25
    • Malpractice RVU 0.03 changed to 0.02
    • Practice expense GPCI 0.911 changed to 0.912
    • Malpractice GPCI 0.618 changed to 0.715

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $52.40changed to$21.10

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 1.27 changed to 0.22
    • Practice expense GPCI 0.909 changed to 0.911
    • Malpractice GPCI 0.520 changed to 0.618

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $52.40

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$21.85$15.06RVU26D
2026-07-01$21.85$15.06RVU26C
2026-04-01$21.85$15.06RVU26B
2026-01-01$21.85$15.06RVU26A
2025-10-01$21.65$17.52RVU25D
2025-07-01$21.65$17.52RVU25C
2025-04-01$21.65$17.52RVU25B
2025-01-01$21.65$17.52RVU25A
2024-10-01$21.98$18.03RVU24D
2024-07-01$21.98$18.03RVU24C
2024-04-01$21.98$18.03RVU24B
2024-03-09$21.98$18.03RVU24AR
2024-01-01$21.62$17.73RVU24A
2023-10-01$21.97$18.59RVU23D
2023-07-01$21.97$18.59RVU23C
2023-04-01$21.97$18.59RVU23B
2023-01-01$21.97$18.59RVU23A
2022-10-01$22.04$18.60RVU22D
2022-07-01$22.04$18.60RVU22C
2022-04-01$22.04$18.60RVU22B
2022-01-01$22.04$18.60RVU22A
2021-10-01$22.22$19.07RVU21D
2021-07-01$22.22$19.07RVU21C
2021-04-01$22.22$19.07RVU21B
2021-01-01$22.22$19.07RVU21A
2020-10-01$22.97$19.70RVU20D
2020-07-01$22.97$19.70RVU20C
2020-04-01$22.97$19.70RVU20B
2020-01-01$22.97$19.70RVU20A
2019-10-01$22.94$19.65RVU19D
2019-07-01$22.94$19.65RVU19C
2019-04-01$22.94$19.65RVU19B
2019-01-01$22.94$19.65RVU19A
2018-10-01$23.24$19.96RVU18D
2018-07-01$23.24$19.96RVU18C
2018-04-01$23.24$19.96RVU18B
2018-01-01$23.24$19.96RVU18AR1
2017-10-01$22.90$19.63RVU17D
2017-07-01$22.90$19.63RVU17C
2017-04-01$22.90$19.63RVU17B
2017-01-01$22.90$19.63RVU17A
2016-10-01$22.25$19.31RVU16D
2016-07-01$22.25$19.31RVU16C
2016-04-01$22.25$19.31RVU16B
2016-01-01$22.25$19.31RVU16A
2015-10-01$22.00$19.05RVU15D
2015-07-01$22.00$19.05RVU15C
2015-04-01$21.89$18.96RVU15B
2015-01-01$21.89$18.96RVU15A
2014-10-01$21.10$18.49RVU14D
2014-07-01$21.10$18.49RVU14C
2014-04-01$21.10$18.49RVU14B
2014-01-01$21.10$18.49RVU14A
2013-10-01$52.40$18.38RVU13D
2013-07-01$52.40$18.38RVU13C
2013-04-01$52.40$18.38RVU13B
2013-01-01$52.40$18.38RVU13AR

Price 88363 for an earlier date of service

Where the South Carolina rate applies

South Carolina is a Medicare payment area, not a city. Our Census mapping connects it to 475 cities and communities in South Carolina. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Abney Crossroads
  • Adams Run
  • Aiken
  • Alcolu
  • Allendale
  • Anderson
  • Andrews

Browse all communities in South Carolina

88363 billing questions

When is 88363 appropriate instead of an in situ hybridization code?

Use 88363 for preparing and conveying previously diagnosed, archived tissue for molecular analysis. In situ hybridization codes describe the assay performed on tissue, not this archive-preparation service.

How many units should be reported?

The code is reported per case. Do not count each slide or tissue piece as a separate case.

Does 88363 include the molecular test?

No. It describes preparation and conveyance of archived tissue; the molecular assay is a separate service when performed and separately reportable.

What documentation supports reporting 88363?

Document the previously diagnosed archived case, the request for molecular analysis, and the preparation and conveyance of tissue for that analysis.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88363PPRRVU2026_Oct_nonQPP.csv, line 11,284 (RVU26D)
Geographic factors for South CarolinaGPCI2026.csv, line 93 (RVU26D)

Open CMS sourceHow we calculate rates

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