CPT code 88369: ISH morphometry, quantitative or semiquantitative2026 Medicare rate & RVUs in Miami, FL
Reports computer-assisted quantitative or semiquantitative morphometric analysis of in situ hybridization, such as probe-based FISH testing.
In Miami, FL, Medicare pays $134.28 for 88369 in the office.
Check a contract rate as a % of Medicare · 88369 nationwide
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 11 sections
What 88369 covers
This service uses computer-assisted image analysis to quantify or semiquantify signals in tissue cells examined by in situ hybridization, including fluorescence in situ hybridization (FISH). A pathologist or laboratory specialist may evaluate probe signals to assess a molecular finding such as gene amplification in a tumor specimen. It is distinct from simply performing or interpreting a routine histologic stain; the work is the morphometric analysis of the ISH result.
Report 88369 as an add-on with the required primary procedure, not by itself; CMS pays it within that procedure’s global period. The record should identify the specimen and probe, describe the computerized quantitative or semiquantitative analysis, and support the reported interpretation. Modifier 26 identifies the professional interpretation, while modifier TC identifies the technical work, including equipment and staff. Reporting without either modifier represents the global service.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
How Miami, FL compares for 88369
Across 109 of 109 payment localities, the office rate for 88369 runs from $113.72 in Arkansas to $177.77 in San Benito County, CA. Miami, FL pays $134.28. The RVUs are the same everywhere; the geographic indexes change the dollars.
- Miami, FL · this page$134.28
- Fort Lauderdale, FL · Florida$130.84−$3.44
- Rest of Florida · Florida$124.62−$9.66
- Los Angeles, CA · California$148.95+$14.67
- Washington, DC area · District of Columbia$149.02+$14.74
- Chicago, IL · Illinois$130.48−$3.80
- Manhattan, NY · New York$147.87+$13.59
Other areas in Florida first, then benchmark localities. Bars start at $0.
Every other payment area
| Payment locality | Office | Facility |
|---|---|---|
| AlaskaAlaska | $146.84 | — |
| AlabamaAlabama | $115.44 | — |
| ArkansasArkansas | $113.72 | — |
| ArizonaArizona | $125.56 | — |
| Bakersfield, CACalifornia | $139.23 | — |
| Chico, CACalifornia | $139.14 | — |
| El Centro, CACalifornia | $139.14 | — |
| Fresno, CACalifornia | $139.14 | — |
| Hanford, CACalifornia | $139.14 | — |
| Madera, CACalifornia | $139.14 | — |
| Merced, CACalifornia | $139.14 | — |
| Modesto, CACalifornia | $139.14 | — |
| Napa, CACalifornia | $163.59 | — |
| Oxnard, CACalifornia | $148.52 | — |
| Redding, CACalifornia | $139.14 | — |
| Rest of CaliforniaCalifornia | $139.14 | — |
| Riverside, CACalifornia | $139.37 | — |
| Sacramento, CACalifornia | $146.64 | — |
| Salinas, CACalifornia | $146.10 | — |
| San Diego, CACalifornia | $149.99 | — |
| Marin County, CACalifornia | $174.00 | — |
| San Francisco, CACalifornia | $173.98 | — |
| San Benito County, CACalifornia | $177.77 | — |
| Santa Clara County, CACalifornia | $177.67 | — |
| San Luis Obispo, CACalifornia | $143.67 | — |
| Santa Cruz, CACalifornia | $151.79 | — |
| Santa Maria, CACalifornia | $146.77 | — |
| Santa Rosa, CACalifornia | $153.36 | — |
| Stockton, CACalifornia | $139.14 | — |
| Vallejo, CACalifornia | $163.56 | — |
| Visalia, CACalifornia | $139.14 | — |
| Yuba City, CACalifornia | $139.14 | — |
| ColoradoColorado | $135.81 | — |
| ConnecticutConnecticut | $137.65 | — |
| DelawareDelaware | $127.71 | — |
| Atlanta, GAGeorgia | $130.82 | — |
| Rest of GeorgiaGeorgia | $117.66 | — |
| Hawaii, Guam, HIHawaii | $143.11 | — |
| IowaIowa | $119.55 | — |
| IdahoIdaho | $120.13 | — |
| East St. Louis, ILIllinois | $121.16 | — |
| Rest of IllinoisIllinois | $120.12 | — |
| Suburban Chicago, ILIllinois | $132.45 | — |
| IndianaIndiana | $120.88 | — |
| KansasKansas | $118.46 | — |
| KentuckyKentucky | $117.15 | — |
| New Orleans, LALouisiana | $122.79 | — |
| Rest of LouisianaLouisiana | $116.76 | — |
| Metropolitan Boston, MAMassachusetts | $150.26 | — |
| Rest of MassachusettsMassachusetts | $134.75 | — |
| Baltimore area, MDMaryland | $137.15 | — |
| Rest of MarylandMaryland | $130.37 | — |
| Rest of MaineMaine | $120.23 | — |
| Southern Maine, MEMaine | $127.73 | — |
| Detroit, MIMichigan | $125.69 | — |
| Rest of MichiganMichigan | $119.83 | — |
| MinnesotaMinnesota | $131.52 | — |
| Metropolitan Kansas City, MOMissouri | $122.47 | — |
| Metropolitan St. Louis, MOMissouri | $123.86 | — |
| Rest of MissouriMissouri | $114.34 | — |
| MississippiMississippi | $114.08 | — |
| MontanaMontana | $128.93 | — |
| North CarolinaNorth Carolina | $121.61 | — |
| North DakotaNorth Dakota | $128.53 | — |
| NebraskaNebraska | $120.38 | — |
| New HampshireNew Hampshire | $133.17 | — |
| Northern New JerseyNew Jersey | $147.29 | — |
| Rest of New JerseyNew Jersey | $139.61 | — |
| New MexicoNew Mexico | $120.30 | — |
| NevadaNevada | $128.92 | — |
| NYC suburbs and Long Island, NYNew York | $150.90 | — |
| Poughkeepsie and northern NYC suburbs, NYNew York | $140.12 | — |
| Queens, NYNew York | $149.89 | — |
| Rest of New YorkNew York | $123.45 | — |
| OhioOhio | $119.75 | — |
| OklahomaOklahoma | $117.48 | — |
| Portland, OROregon | $140.84 | — |
| Rest of OregonOregon | $128.31 | — |
| Metropolitan Philadelphia, PAPennsylvania | $133.79 | — |
| Rest of PennsylvaniaPennsylvania | $120.24 | — |
| Puerto RicoPuerto Rico | $130.08 | — |
| Rhode IslandRhode Island | $132.77 | — |
| South CarolinaSouth Carolina | $120.81 | — |
| South DakotaSouth Dakota | $128.48 | — |
| TennesseeTennessee | $119.01 | — |
| Austin, TXTexas | $135.02 | — |
| Beaumont, TXTexas | $119.38 | — |
| Brazoria, TXTexas | $128.01 | — |
| Dallas, TXTexas | $128.61 | — |
| Fort Worth, TXTexas | $127.57 | — |
| Galveston, TXTexas | $128.26 | — |
| Houston, TXTexas | $128.62 | — |
| Rest of TexasTexas | $123.48 | — |
| UtahUtah | $122.53 | — |
| VirginiaVirginia | $126.94 | — |
| Virgin Islands, VIUnited States Virgin Islands | $130.08 | — |
| VermontVermont | $127.54 | — |
| Rest of WashingtonWashington | $134.66 | — |
| King County, WAWashington | $153.90 | — |
| WisconsinWisconsin | $124.03 | — |
| West VirginiaWest Virginia | $115.39 | — |
| WyomingWyoming | $128.75 | — |
88369 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$113.72
$158.45
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $146.84 | 1 |
| AL | $115.44 | 1 |
| AR | $113.72 | 1 |
| AZ | $125.56 | 1 |
| CA | $139.14–$177.77 | 29 |
| CO | $135.81 | 1 |
| CT | $137.65 | 1 |
| DC | $149.02 | 1 |
| DE | $127.71 | 1 |
| FL | $124.62–$134.28 | 3 |
| GA | $117.66–$130.82 | 2 |
| GU | $143.11 | 1 |
| HI | $143.11 | 1 |
| IA | $119.55 | 1 |
| ID | $120.13 | 1 |
| IL | $120.12–$132.45 | 4 |
| IN | $120.88 | 1 |
| KS | $118.46 | 1 |
| KY | $117.15 | 1 |
| LA | $116.76–$122.79 | 2 |
| MA | $134.75–$150.26 | 2 |
| MD | $130.37–$149.02 | 3 |
| ME | $120.23–$127.73 | 2 |
| MI | $119.83–$125.69 | 2 |
| MN | $131.52 | 1 |
| MO | $114.34–$123.86 | 3 |
| MS | $114.08 | 1 |
| MT | $128.93 | 1 |
| NC | $121.61 | 1 |
| ND | $128.53 | 1 |
| NE | $120.38 | 1 |
| NH | $133.17 | 1 |
| NJ | $139.61–$147.29 | 2 |
| NM | $120.30 | 1 |
| NV | $128.92 | 1 |
| NY | $123.45–$150.90 | 5 |
| OH | $119.75 | 1 |
| OK | $117.48 | 1 |
| OR | $128.31–$140.84 | 2 |
| PA | $120.24–$133.79 | 2 |
| PR | $130.08 | 1 |
| RI | $132.77 | 1 |
| SC | $120.81 | 1 |
| SD | $128.48 | 1 |
| TN | $119.01 | 1 |
| TX | $119.38–$135.02 | 8 |
| UT | $122.53 | 1 |
| VA | $126.94–$149.02 | 2 |
| VI | $130.08 | 1 |
| VT | $127.54 | 1 |
| WA | $134.66–$153.90 | 2 |
| WI | $124.03 | 1 |
| WV | $115.39 | 1 |
| WY | $128.75 | 1 |
How the 88369 rate is calculated
Each of 88369’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · 88369
RVUs × geographic indexes × conversion factor
Work0.68
0.68 RVUs× 1.000 GPCI
Practice expense3.16
3.16 RVUs× 1.000 GPCI
Malpractice0.02
0.02 RVUs× 1.000 GPCI
Adjusted RVUs
3.8600
Conversion factor
$33.4009
Medicare rate
$128.93
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
The exact Miami, FL inputs and CMS source lines
PPRRVU2026_Oct_nonQPP.csv
11,300
- Code
- 88369
- Physician work
- 0.68
- Practice expense
- 3.16
- Malpractice
- 0.02
GPCI2026.csv
42
- Locality
- Miami, FL
- Physician work
- 1.000
- Practice expense
- 1.041
- Malpractice
- 2.529
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.68 | × 1.000 | 0.6800 |
| Practice expense | 3.16 | × 1.041 | 3.2896 |
| Malpractice | 0.02 | × 2.529 | 0.0506 |
| Total RVUs | 4.0201 | ||
| Conversion factor | × 33.4009 | ||
Office rate, Miami, FL$134.28
Office: (0.68 × 1 + 3.16 × 1.041 + 0.02 × 2.529) × $33.4009 = $134.28
Payment rules and modifiers for 88369
The CMS indicators that decide how 88369 is paid alongside other services.
CMS payment indicators · 88369
ISH morphometry, quantitative or semiquantitative
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 1 | Diagnostic test with separate professional (26) and technical (TC) components. |
What modifiers do to the payment
Modifier 26 · payment effect
With and without the modifier
88369 without 26 · national office
$128.93
ISH morphometry, quantitative or semiquantitative
88369-26 · Professional component
$32.06
Pays only the interpretation and report.
How 88369 has changed in Miami, FL
88369 · Office / nonfacility
$134.28
Effective 2026-10-01
The base rate is $3.72 higher than on 2025-10-01, moving from $130.56 to $134.28 (2.8%).
It is unchanged from the immediately preceding available release, effective 2026-07-01.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2026
RVU26A
$130.56changed to$134.28
- Conversion factor 32.3465 changed to 33.4009
- Work RVU 0.70 changed to 0.68
- Practice expense RVU 3.20 changed to 3.16
- Practice expense GPCI 1.027 changed to 1.041
- Malpractice GPCI 2.500 changed to 2.529
Held through RVU26B, RVU26C, RVU26D.
January 1, 2025
RVU25A
$131.97changed to$130.56
- Conversion factor 33.2875 changed to 32.3465
- Practice expense RVU 3.13 changed to 3.20
Held through RVU25B, RVU25C, RVU25D.
March 9, 2024
RVU24AR
$129.81changed to$131.97
- Conversion factor 32.7442 changed to 33.2875
Held through RVU24B, RVU24C, RVU24D.
January 1, 2024
RVU24A
$126.88changed to$129.81
- Conversion factor 33.8872 changed to 32.7442
- Practice expense RVU 2.92 changed to 3.13
- Practice expense GPCI 1.025 changed to 1.027
- Malpractice GPCI 2.564 changed to 2.500
January 1, 2023
RVU23A
$120.21changed to$126.88
- Conversion factor 34.6062 changed to 33.8872
- Practice expense RVU 2.66 changed to 2.92
- Practice expense GPCI 1.023 changed to 1.025
- Malpractice GPCI 2.629 changed to 2.564
Held through RVU23B, RVU23C, RVU23D.
January 1, 2022
RVU22A
$121.57changed to$120.21
- Conversion factor 34.8931 changed to 34.6062
- Practice expense RVU 2.67 changed to 2.66
Held through RVU22B, RVU22C, RVU22D.
January 1, 2021
RVU21A
$120.08changed to$121.57
- Conversion factor 36.0896 changed to 34.8931
- Practice expense RVU 2.51 changed to 2.67
- Practice expense GPCI 1.026 changed to 1.023
- Malpractice GPCI 2.598 changed to 2.629
Held through RVU21B, RVU21C, RVU21D.
January 1, 2020
RVU20A
$116.82changed to$120.08
- Conversion factor 36.0391 changed to 36.0896
- Practice expense RVU 2.42 changed to 2.51
- Practice expense GPCI 1.029 changed to 1.026
- Malpractice GPCI 2.566 changed to 2.598
Held through RVU20B, RVU20C, RVU20D.
January 1, 2019
RVU19A
$115.21changed to$116.82
- Conversion factor 35.9996 changed to 36.0391
- Practice expense RVU 2.38 changed to 2.42
Held through RVU19B, RVU19C, RVU19D.
January 1, 2018
RVU18AR1
$112.04changed to$115.21
- Conversion factor 35.8887 changed to 35.9996
- Practice expense RVU 2.30 changed to 2.38
- Practice expense GPCI 1.031 changed to 1.029
- Malpractice GPCI 2.528 changed to 2.566
Held through RVU18B, RVU18C, RVU18D.
January 1, 2017
RVU17A
$112.32changed to$112.04
- Conversion factor 35.8043 changed to 35.8887
- Work RVU 0.67 changed to 0.70
- Practice expense RVU 2.34 changed to 2.30
- Practice expense GPCI 1.033 changed to 1.031
- Malpractice GPCI 2.490 changed to 2.528
Held through RVU17B, RVU17C, RVU17D.
January 1, 2016
RVU16A
$76.88changed to$112.32
- Conversion factor 35.9335 changed to 35.8043
- Work RVU 0.53 changed to 0.67
- Practice expense RVU 1.51 changed to 2.34
Held through RVU16B, RVU16C, RVU16D.
July 1, 2015
RVU15C
$76.50changed to$76.88
- Conversion factor 35.7547 changed to 35.9335
Held through RVU15D.
January 1, 2015
RVU15A
No ratechanged to$76.50
Held through RVU15B.
January 1, 2013
RVU13AR
Earliest loaded release: No rate
Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D.
| Effective from | Office | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | $134.28 | Not available in this setting | RVU26D |
| 2026-07-01 | $134.28 | Not available in this setting | RVU26C |
| 2026-04-01 | $134.28 | Not available in this setting | RVU26B |
| 2026-01-01 | $134.28 | Not available in this setting | RVU26A |
| 2025-10-01 | $130.56 | Not available in this setting | RVU25D |
| 2025-07-01 | $130.56 | Not available in this setting | RVU25C |
| 2025-04-01 | $130.56 | Not available in this setting | RVU25B |
| 2025-01-01 | $130.56 | Not available in this setting | RVU25A |
| 2024-10-01 | $131.97 | Not available in this setting | RVU24D |
| 2024-07-01 | $131.97 | Not available in this setting | RVU24C |
| 2024-04-01 | $131.97 | Not available in this setting | RVU24B |
| 2024-03-09 | $131.97 | Not available in this setting | RVU24AR |
| 2024-01-01 | $129.81 | Not available in this setting | RVU24A |
| 2023-10-01 | $126.88 | Not available in this setting | RVU23D |
| 2023-07-01 | $126.88 | Not available in this setting | RVU23C |
| 2023-04-01 | $126.88 | Not available in this setting | RVU23B |
| 2023-01-01 | $126.88 | Not available in this setting | RVU23A |
| 2022-10-01 | $120.21 | Not available in this setting | RVU22D |
| 2022-07-01 | $120.21 | Not available in this setting | RVU22C |
| 2022-04-01 | $120.21 | Not available in this setting | RVU22B |
| 2022-01-01 | $120.21 | Not available in this setting | RVU22A |
| 2021-10-01 | $121.57 | Not available in this setting | RVU21D |
| 2021-07-01 | $121.57 | Not available in this setting | RVU21C |
| 2021-04-01 | $121.57 | Not available in this setting | RVU21B |
| 2021-01-01 | $121.57 | Not available in this setting | RVU21A |
| 2020-10-01 | $120.08 | Not available in this setting | RVU20D |
| 2020-07-01 | $120.08 | Not available in this setting | RVU20C |
| 2020-04-01 | $120.08 | Not available in this setting | RVU20B |
| 2020-01-01 | $120.08 | Not available in this setting | RVU20A |
| 2019-10-01 | $116.82 | Not available in this setting | RVU19D |
| 2019-07-01 | $116.82 | Not available in this setting | RVU19C |
| 2019-04-01 | $116.82 | Not available in this setting | RVU19B |
| 2019-01-01 | $116.82 | Not available in this setting | RVU19A |
| 2018-10-01 | $115.21 | Not available in this setting | RVU18D |
| 2018-07-01 | $115.21 | Not available in this setting | RVU18C |
| 2018-04-01 | $115.21 | Not available in this setting | RVU18B |
| 2018-01-01 | $115.21 | Not available in this setting | RVU18AR1 |
| 2017-10-01 | $112.04 | Not available in this setting | RVU17D |
| 2017-07-01 | $112.04 | Not available in this setting | RVU17C |
| 2017-04-01 | $112.04 | Not available in this setting | RVU17B |
| 2017-01-01 | $112.04 | Not available in this setting | RVU17A |
| 2016-10-01 | $112.32 | Not available in this setting | RVU16D |
| 2016-07-01 | $112.32 | Not available in this setting | RVU16C |
| 2016-04-01 | $112.32 | Not available in this setting | RVU16B |
| 2016-01-01 | $112.32 | Not available in this setting | RVU16A |
| 2015-10-01 | $76.88 | Not available in this setting | RVU15D |
| 2015-07-01 | $76.88 | Not available in this setting | RVU15C |
| 2015-04-01 | $76.50 | Not available in this setting | RVU15B |
| 2015-01-01 | $76.50 | Not available in this setting | RVU15A |
| 2014-10-01 | Not in this release | Not in this release | RVU14D |
| 2014-07-01 | Not in this release | Not in this release | RVU14C |
| 2014-04-01 | Not in this release | Not in this release | RVU14B |
| 2014-01-01 | Not in this release | Not in this release | RVU14A |
| 2013-10-01 | Not in this release | Not in this release | RVU13D |
| 2013-07-01 | Not in this release | Not in this release | RVU13C |
| 2013-04-01 | Not in this release | Not in this release | RVU13B |
| 2013-01-01 | Not in this release | Not in this release | RVU13AR |
Where the Miami, FL rate applies
Miami, FL is a Medicare payment area, not a city. Our Census mapping connects it to 83 cities and communities in Florida. Some span more than one payment area; confirm with the service ZIP.
- Miami
- Aventura
- Bal Harbour
- Bay Harbor Islands
- Big Coppitt Key
- Big Pine Key
- Biscayne Gardens
- Biscayne Park
88369 billing questions
Can 88369 be reported by itself?
No. CMS identifies it as an add-on code, so it must be billed with a primary procedure and is paid within that procedure’s global period.
When should 88369 be distinguished from 88373?
88369 is for the initial single-probe stain procedure in this morphometric analysis series. 88373 is for each additional single-probe stain procedure.
How are modifiers 26 and TC used?
Use modifier 26 for the professional interpretation and modifier TC for the technical service. Without either modifier, the claim represents the global service.
What documentation supports 88369?
Document the specimen and probe evaluated, the computer-assisted quantitative or semiquantitative analysis performed, and the resulting interpretation.
Is 88369 a test for routine immunohistochemistry?
No. It describes morphometric analysis of in situ hybridization. Tumor immunohistochemistry analysis is represented by a different code family.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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