CPT code 88369: ISH morphometry, quantitative or semiquantitative2026 Medicare rate & RVUs in Wyoming

In Wyoming, Medicare pays $128.75 for 88369 in the office.

Check a contract rate as a % of Medicare · 88369 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What 88369 covers

This service uses computer-assisted image analysis to quantify or semiquantify signals in tissue cells examined by in situ hybridization, including fluorescence in situ hybridization (FISH). A pathologist or laboratory specialist may evaluate probe signals to assess a molecular finding such as gene amplification in a tumor specimen. It is distinct from simply performing or interpreting a routine histologic stain; the work is the morphometric analysis of the ISH result.

Report 88369 as an add-on with the required primary procedure, not by itself; CMS pays it within that procedure’s global period. The record should identify the specimen and probe, describe the computerized quantitative or semiquantitative analysis, and support the reported interpretation. Modifier 26 identifies the professional interpretation, while modifier TC identifies the technical work, including equipment and staff. Reporting without either modifier represents the global service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Wyoming compares for 88369

Across 109 of 109 payment localities, the office rate for 88369 runs from $113.72 in Arkansas to $177.77 in San Benito County, CA. Wyoming pays $128.75. The RVUs are the same everywhere; the geographic indexes change the dollars.

Every other payment area

88369 rates by state

Office rate range in each state. Select a state to see its payment localities.

See 88369 in every payment locality

How the 88369 rate is calculated

Each of 88369’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for 88369

The CMS indicators that decide how 88369 is paid alongside other services.

What modifiers do to the payment

When to use modifier 26

Codes related to 88369

Related codes aren’t interchangeable: bill the code that matches the service performed.

How 88369 has changed in Wyoming

Price 88369 for an earlier date of service

Where the Wyoming rate applies

Wyoming is a Medicare payment area, not a city. Our Census mapping connects it to 205 cities and communities in Wyoming. Some span more than one payment area; confirm with the service ZIP.

• Afton
• Albany
• Albin
• Alcova
• Alpine
• Alpine Northeast
• Alpine Northwest
• Alta

Browse all communities in Wyoming

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates