CPT code 95149: Venom antigen preparation, five or more venoms2026 Medicare rate & RVUs

Medicare pays $118.57 for 95149 nationally in the office and $2.67 in a hospital or facility. Local office rates run $102.02–$170.01.

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What 95149 covers

This service covers the supervision of preparing and supplying venom antigens for allergen immunotherapy when the treatment includes five or more distinct stinging-insect venoms. An allergist or other qualified clinician typically arranges this work in an allergy practice; the prepared extracts may include venoms such as honeybee, yellow jacket, or hornet. The service concerns the antigen preparation and provision, not the injection given to the patient.

Choose this level based on the number of distinct venom types prepared for the patient, rather than the number of injections or visits. The record should support the venom types and the preparation and provision performed. CMS assigns physician fee schedule relative values for work, practice expense, and malpractice; the practice-expense value differs between office and facility settings. Report a separate, appropriate immunotherapy administration service when an injection is also given, supported by the service documentation.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 95149 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

95149 rates by state

Office rate range in each state. Select a state to see its payment localities.

How the 95149 rate is calculated

Each of 95149’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for 95149

95149 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

95149 compared with similar codes

How to choose

95148Venom antigen preparationFour insect venoms

Use 95148 when the prepared immunotherapy includes four distinct stinging-insect venoms. Use 95149 for five or more.

95165Allergy extract preparationMultidose vials, per dose

95149 identifies preparation and provision at the five-or-more stinging-insect venom level. 95165 is a different antigen-preparation service, not a venom-count substitute.

95134Venom immunotherapyFive insect types

95134 represents the immunotherapy administration service for five or more stinging-insect venoms. 95149 represents preparation and provision of the venom antigens.

Codes related to 95149

Related codes aren’t interchangeable: bill the code that matches the service performed.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates