CPT code 96366: IV infusion add-on hour, therapeutic or diagnostic, each additional hour2026 Medicare rate & RVUs

Medicare pays $21.38 for 96366 nationally in the office. Local office rates run $19.10–$28.53.

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What 96366 covers

This code captures continued IV administration of a therapeutic, prophylactic, or diagnostic drug after the infusion's first hour. Examples include standard infusions of IV antibiotics, iron, and immune globulin. In a physician office or infusion suite, an infusion nurse or other clinical staff typically starts, monitors, and stops the infusion under physician supervision. The substance administered and the service's complexity determine whether this infusion family is appropriate.

Report 96366 with 96365 when an initial drug infusion lasts at least 91 minutes. It can also extend a qualifying sequential infusion reported with 96367 and its required primary administration code. Report one unit for each additional hour that meets the time threshold; a final increment must exceed 30 minutes. Record the start and stop times for each drug, along with its identity, dose, and route. CMS treats 96366 as an add-on paid within the primary procedure's global period, so it cannot be billed alone. As an incident-to service, it is billed only when performed under physician supervision. Report a separately billable drug supply with its appropriate HCPCS code and units.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 96366 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

96366 rates by state

Office rate range in each state. Select a state to see its payment localities.

How the 96366 rate is calculated

Each of 96366’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for 96366

The CMS indicators that decide how 96366 is paid alongside other services.

96366 compared with similar codes

How to choose

96365IV drug infusionInitial, first hour

96365 reports the initial therapeutic, prophylactic, or diagnostic IV infusion. For a single-drug infusion, add 96366 when administration reaches 91 minutes.

96361IV hydrationEach additional hour

96361 reports an additional hour of IV hydration. Use 96366 for qualifying additional time administering a therapeutic, prophylactic, or diagnostic drug.

96415Chemo infusion add-onEach additional hour

96415 extends chemotherapy or other highly complex infusion administration. Use 96366 when the drug and administration qualify for the standard therapeutic infusion family.

96367Sequential IV infusionAdditional drug, up to one hour

96367 reports a sequential infusion of a new drug after another administration service. Add 96366 when that sequential infusion has qualifying time beyond its first hour.

Codes related to 96366

Related codes aren’t interchangeable: bill the code that matches the service performed.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates