CPT code 96405: Intralesional chemotherapy, up to seven lesions2026 Medicare rate & RVUs in Vallejo, CA

Report 96405 when an antineoplastic drug is administered directly into one to seven lesions, such as in a dermatology or oncology setting.

CMS RVU26DEffective Oct 1, 2026One payment locality30.7K Medicare services in 2024

In Vallejo, CA, Medicare pays $106.09 for 96405 in the office and $25.97 when it’s performed in a hospital or facility.

$106.09Office (non-facility)
$25.97Hospital or facility
+25.6%vs the national office rate ($84.50)

Check a contract rate as a % of Medicare · 96405 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 96405 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Vallejo, CA
  2. What 96405 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 96405 covers

A physician or other qualified practitioner reports 96405 for administering chemotherapy directly into one or more lesions, with the code covering up to seven lesions. This is a local injection into the lesions, rather than systemic chemotherapy given subcutaneously, intramuscularly, or intravenously. Dermatology and oncology practices commonly provide this service for selected cutaneous lesions; the code represents the administration, not the drug product.

Document the antineoplastic agent, intralesional route, treated sites, and lesion count. Use the code for one through seven lesions; when more than seven are treated, compare the service with 96406. CMS assigns a 0-day global period, so same-day preoperative and postoperative care is included. When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% reduction. Modifier 50 is inappropriate. CMS does not pay an assistant at surgery for this service, and co-surgeon and team-surgery billing are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Vallejo, CA compares for 96405

Across 109 of 109 payment localities, the office rate for 96405 runs from $74.69 in Arkansas to $115.18 in San Benito County, CA. Vallejo, CA pays $106.09. The RVUs are the same everywhere; the geographic indexes change the dollars.

96405 in Vallejo, CA vs other payment areas
  1. Vallejo, CA · this page$106.09
  2. Bakersfield, CA · California$90.79−$15.30
  3. Chico, CA · California$90.68−$15.41
  4. El Centro, CA · California$90.69−$15.40
  5. Fresno, CA · California$90.68−$15.41
  6. Hanford, CA · California$90.68−$15.41
  7. Los Angeles, CA · California$96.98−$9.11

Other areas in California first, then benchmark localities. Bars start at $0.

Every other payment area

96405 in every other Medicare payment locality
Payment localityOfficeFacility
Madera, CACalifornia$90.68$24.06
Merced, CACalifornia$90.68$24.06
Modesto, CACalifornia$90.68$24.06
Napa, CACalifornia$106.14$26.02
Oxnard, CACalifornia$96.65$24.80
Redding, CACalifornia$90.68$24.06
Rest of CaliforniaCalifornia$90.68$24.06
Riverside, CACalifornia$91.02$24.39

96405 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$74.69

$102.93

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
96405 office rate range by state
State / territoryOffice rate rangeLocalities
AK$97.041
AL$75.801
AR$74.691
AZ$82.311
CA$90.68–$115.1829
CO$88.731
CT$90.151
DC$97.331
DE$83.701
FL$82.10–$88.753
GA$77.55–$85.822
GU$93.141
HI$93.141
IA$78.281
ID$78.691
IL$79.31–$87.194
IN$79.161
KS$77.661
KY$77.081
LA$76.86–$80.742
MA$88.08–$97.942
MD$85.39–$97.333
ME$78.83–$83.542
MI$78.88–$82.882
MN$85.721
MO$75.35–$81.333
MS$75.051
MT$84.501
NC$79.711
ND$83.911
NE$78.791
NH$87.091
NJ$91.38–$96.252
NM$79.221
NV$84.401
NY$80.90–$98.975
OH$78.761
OK$77.201
OR$83.94–$91.872
PA$79.03–$87.722
PR$85.221
RI$86.911
SC$79.331
SD$83.841
TN$78.021
TX$78.48–$88.268
UT$80.431
VA$83.09–$97.332
VI$85.221
VT$83.351
WA$88.00–$100.202
WI$81.031
WV$76.271
WY$84.241

See 96405 in every payment locality

How the 96405 rate is calculated

Each of 96405’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 96405

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.52

0.52 RVUs× 1.000 GPCI

Practice expense1.98

1.98 RVUs× 1.000 GPCI

Malpractice0.03

0.03 RVUs× 1.000 GPCI

Adjusted RVUs

2.5300

Conversion factor

$33.4009

Medicare rate

$84.50

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Vallejo, CA inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

12,797

Code
96405
Physician work
0.52
Practice expense
1.98
Malpractice
0.03

GPCI2026.csv

33

Locality
Vallejo, CA
Physician work
1.063
Practice expense
1.318
Malpractice
0.459
Office calculation for 96405 in Vallejo, CA
ComponentRVULocality factorAdjusted
Physician work0.52× 1.0630.5528
Practice expense1.98× 1.3182.6096
Malpractice0.03× 0.4590.0138
Total RVUs3.1762
Conversion factor× 33.4009

Office rate, Vallejo, CA$106.09

Office: (0.52 × 1.063 + 1.98 × 1.318 + 0.03 × 0.459) × $33.4009 = $106.09

Facility: (0.52 × 1.063 + 0.16 × 1.318 + 0.03 × 0.459) × $33.4009 = $25.97

Open 96405 in the RVU calculator

Payment rules and modifiers for 96405

The CMS indicators that decide how 96405 is paid alongside other services.

CMS payment indicators · 96405

Intralesional chemotherapy, up to seven lesions

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

96405 without 51 · national office

$84.50

Intralesional chemotherapy, up to seven lesions

96405-51 · Second procedure: 50%

$42.25

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

How 96405 has changed in Vallejo, CA

96405 · Office / nonfacility

$106.09

Effective 2026-10-01

The base rate is $6.90 higher than on 2025-10-01, moving from $99.19 to $106.09 (7.0%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $99.19changed to$106.09

    • Conversion factor 32.3465 changed to 33.4009
    • Practice expense RVU 1.91 changed to 1.98
    • Work GPCI 1.058 changed to 1.063
    • Practice expense GPCI 1.310 changed to 1.318
    • Malpractice GPCI 0.470 changed to 0.459

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $103.38changed to$99.19

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 1.94 changed to 1.91

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $101.69changed to$103.38

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $102.77changed to$101.69

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 1.95 changed to 1.94
    • Malpractice RVU 0.04 changed to 0.03
    • Work GPCI 1.051 changed to 1.058
    • Practice expense GPCI 1.265 changed to 1.310
    • Malpractice GPCI 0.487 changed to 0.470
  5. January 1, 2023

    RVU23A

    $101.81changed to$102.77

    • Conversion factor 34.6062 changed to 33.8872
    • Work GPCI 1.044 changed to 1.051
    • Practice expense GPCI 1.220 changed to 1.265
    • Malpractice GPCI 0.504 changed to 0.487

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $102.66changed to$101.81

    • Conversion factor 34.8931 changed to 34.6062

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $100.65changed to$102.66

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 1.80 changed to 1.95
    • Malpractice RVU 0.03 changed to 0.04
    • Work GPCI 1.049 changed to 1.044
    • Practice expense GPCI 1.238 changed to 1.220
    • Malpractice GPCI 0.496 changed to 0.504

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $99.93changed to$100.65

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 1.76 changed to 1.80
    • Work GPCI 1.055 changed to 1.049
    • Practice expense GPCI 1.256 changed to 1.238
    • Malpractice GPCI 0.458 changed to 0.496

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $98.92changed to$99.93

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 1.74 changed to 1.76

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $100.52changed to$98.92

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 1.76 changed to 1.74
    • Work GPCI 1.057 changed to 1.055
    • Practice expense GPCI 1.271 changed to 1.256
    • Malpractice GPCI 0.477 changed to 0.458

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    No ratechanged to$100.52

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$106.09$25.97RVU26D
2026-07-01$106.09$25.97RVU26C
2026-04-01$106.09$25.97RVU26B
2026-01-01$106.09$25.97RVU26A
2025-10-01$99.19$31.39RVU25D
2025-07-01$99.19$31.39RVU25C
2025-04-01$99.19$31.39RVU25B
2025-01-01$99.19$31.39RVU25A
2024-10-01$103.38$31.86RVU24D
2024-07-01$103.38$31.86RVU24C
2024-04-01$103.38$31.86RVU24B
2024-03-09$103.38$31.86RVU24AR
2024-01-01$101.69$31.34RVU24A
2023-10-01$102.77$32.04RVU23D
2023-07-01$102.77$32.04RVU23C
2023-04-01$102.77$32.04RVU23B
2023-01-01$102.77$32.04RVU23A
2022-10-01$101.81$31.31RVU22D
2022-07-01$101.81$31.31RVU22C
2022-04-01$101.81$31.31RVU22B
2022-01-01$101.81$31.31RVU22A
2021-10-01$102.66$31.57RVU21D
2021-07-01$102.66$31.57RVU21C
2021-04-01$102.66$31.57RVU21B
2021-01-01$102.66$31.57RVU21A
2020-10-01$100.65$33.18RVU20D
2020-07-01$100.65$33.18RVU20C
2020-04-01$100.65$33.18RVU20B
2020-01-01$100.65$33.18RVU20A
2019-10-01$99.93$33.39RVU19D
2019-07-01$99.93$33.39RVU19C
2019-04-01$99.93$33.39RVU19B
2019-01-01$99.93$33.39RVU19A
2018-10-01$98.92$33.81RVU18D
2018-07-01$98.92$33.81RVU18C
2018-04-01$98.92$33.81RVU18B
2018-01-01$98.92$33.81RVU18AR1
2017-10-01$100.52$34.38RVU17D
2017-07-01$100.52$34.38RVU17C
2017-04-01$100.52$34.38RVU17B
2017-01-01$100.52$34.38RVU17A
2016-10-01Rate data unavailableRate data unavailableRVU16D
2016-07-01Rate data unavailableRate data unavailableRVU16C
2016-04-01Rate data unavailableRate data unavailableRVU16B
2016-01-01Rate data unavailableRate data unavailableRVU16A
2015-10-01Rate data unavailableRate data unavailableRVU15D
2015-07-01Rate data unavailableRate data unavailableRVU15C
2015-04-01Rate data unavailableRate data unavailableRVU15B
2015-01-01Rate data unavailableRate data unavailableRVU15A
2014-10-01Rate data unavailableRate data unavailableRVU14D
2014-07-01Rate data unavailableRate data unavailableRVU14C
2014-04-01Rate data unavailableRate data unavailableRVU14B
2014-01-01Rate data unavailableRate data unavailableRVU14A
2013-10-01Rate data unavailableRate data unavailableRVU13D
2013-07-01Rate data unavailableRate data unavailableRVU13C
2013-04-01Rate data unavailableRate data unavailableRVU13B
2013-01-01Rate data unavailableRate data unavailableRVU13AR

Price 96405 for an earlier date of service

Where the Vallejo, CA rate applies

Vallejo, CA is a Medicare payment area, not a city. Our Census mapping connects it to 11 cities and communities in California. Some span more than one payment area; confirm with the service ZIP.

  • Vallejo
  • Allendale
  • Benicia
  • Dixon
  • Elmira
  • Fairfield
  • Green Valley
  • Hartley

Browse all communities in California

96405 billing questions

How many lesions can be reported with 96405?

96405 covers administration into one through seven lesions. For treatment of more than seven lesions, compare the service with 96406 rather than reporting 96405 for every lesion.

How is 96405 different from 11900?

96405 is for intralesional chemotherapy. Code 11900 is for intralesional injection of a substance other than chemotherapy, for up to seven lesions.

Is the chemotherapy drug included in 96405?

No. The code represents administration; report a separately payable drug product under its applicable code when the practice supplies it and documentation supports separate reporting.

Should modifier 50 be used when lesions are on both sides?

No. CMS identifies bilateral adjustment as inappropriate for 96405. Report the service based on the number of treated lesions, not as a bilateral procedure.

What documentation supports 96405?

Record the drug, intralesional route, lesion locations, and number of lesions treated. The count supports choosing 96405 for up to seven lesions or 96406 for more than seven.

How does CMS handle other procedures performed in the same session?

The highest-valued procedure is paid in full, and other procedures in the same session are subject to the standard multiple procedure reduction. CMS does not pay an assistant at surgery for 96405.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 96405PPRRVU2026_Oct_nonQPP.csv, line 12,797 (RVU26D)
Geographic factors for Vallejo, CAGPCI2026.csv, line 33 (RVU26D)

Open CMS sourceHow we calculate rates

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