CPT code 96413: Chemo IV infusion, initial drug, first hour2026 Medicare rate & RVUs in Puerto Rico
Report the initial hour of intravenous antineoplastic or qualifying highly complex biologic infusion when the drug runs longer than 15 minutes.
In Puerto Rico, Medicare pays $134.57 for 96413 in the office.
Check a contract rate as a % of Medicare · 96413 nationwide
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 11 sections
What 96413 covers
Code 96413 captures the initial hour of an intravenous antineoplastic infusion or an infusion of another agent that meets chemotherapy administration requirements for high-complexity biologic therapy. Oncology nurses commonly administer these treatments in physician offices or outpatient infusion suites under an oncologist’s or hematologist’s supervision. Paclitaxel or carboplatin infusions are familiar examples. Nursing work includes preparing the infusion, assessing the patient, monitoring for reactions, and ending the infusion; classification as a monoclonal antibody alone does not establish eligibility for chemotherapy administration coding.
Report one initial administration service per encounter unless separate medically necessary IV sites support distinct initial services. Record the drug and actual start and stop times; infusion lasting more than 15 minutes supports 96413, and 96415 begins only when the infusion exceeds 90 minutes. Sequential chemotherapy drugs and separately administered premedications or hydration may support additional administration codes when their requirements are met. The IV start, routine flush, and usual supplies are included; report separately payable drug products with appropriate HCPCS codes. CMS classifies 96413 as an incident-to service, billed only when performed under physician supervision.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
How Puerto Rico compares for 96413
Across 109 of 109 payment localities, the office rate for 96413 runs from $114.99 in Arkansas to $186.95 in San Benito County, CA. Puerto Rico pays $134.57. The RVUs are the same everywhere; the geographic indexes change the dollars.
- Puerto Rico · this page$134.57
- Los Angeles, CA · California$155.12+$20.55
- Washington, DC area · District of Columbia$155.68+$21.11
- Miami, FL · Florida$141.83+$7.26
- Chicago, IL · Illinois$136.97+$2.40
- Manhattan, NY · New York$154.93+$20.36
- Alaska · Alaska$144.80+$10.23
Other areas in Puerto Rico first, then benchmark localities. Bars start at $0.
Every other payment area
| Payment locality | Office | Facility |
|---|---|---|
| AlabamaAlabama | $117.06 | — |
| ArkansasArkansas | $114.99 | — |
| ArizonaArizona | $129.16 | — |
| Bakersfield, CACalifornia | $144.20 | — |
| Chico, CACalifornia | $144.02 | — |
| El Centro, CACalifornia | $144.03 | — |
| Fresno, CACalifornia | $144.02 | — |
| Hanford, CACalifornia | $144.02 | — |
| Madera, CACalifornia | $144.02 | — |
| Merced, CACalifornia | $144.02 | — |
| Modesto, CACalifornia | $144.02 | — |
| Napa, CACalifornia | $171.37 | — |
| Oxnard, CACalifornia | $154.78 | — |
| Redding, CACalifornia | $144.02 | — |
| Rest of CaliforniaCalifornia | $144.02 | — |
| Riverside, CACalifornia | $144.77 | — |
| Sacramento, CACalifornia | $152.34 | — |
| Salinas, CACalifornia | $151.81 | — |
| San Diego, CACalifornia | $156.31 | — |
| Marin County, CACalifornia | $182.74 | — |
| San Francisco, CACalifornia | $182.66 | — |
| San Benito County, CACalifornia | $186.95 | — |
| Santa Clara County, CACalifornia | $186.63 | — |
| San Luis Obispo, CACalifornia | $149.24 | — |
| Santa Cruz, CACalifornia | $158.52 | — |
| Santa Maria, CACalifornia | $152.63 | — |
| Santa Rosa, CACalifornia | $160.19 | — |
| Stockton, CACalifornia | $144.02 | — |
| Vallejo, CACalifornia | $171.26 | — |
| Visalia, CACalifornia | $144.02 | — |
| Yuba City, CACalifornia | $144.02 | — |
| ColoradoColorado | $140.65 | — |
| ConnecticutConnecticut | $143.31 | — |
| DelawareDelaware | $131.62 | — |
| Fort Lauderdale, FLFlorida | $136.74 | — |
| Rest of FloridaFlorida | $129.10 | — |
| Atlanta, GAGeorgia | $135.71 | — |
| Rest of GeorgiaGeorgia | $120.59 | — |
| Hawaii, Guam, HIHawaii | $148.94 | — |
| IowaIowa | $121.53 | — |
| IdahoIdaho | $122.31 | — |
| East St. Louis, ILIllinois | $125.91 | — |
| Rest of IllinoisIllinois | $124.01 | — |
| Suburban Chicago, ILIllinois | $138.42 | — |
| IndianaIndiana | $123.19 | — |
| KansasKansas | $120.44 | — |
| KentuckyKentucky | $119.58 | — |
| New Orleans, LALouisiana | $126.41 | — |
| Rest of LouisianaLouisiana | $119.19 | — |
| Metropolitan Boston, MAMassachusetts | $156.98 | — |
| Rest of MassachusettsMassachusetts | $139.39 | — |
| Baltimore area, MDMaryland | $142.85 | — |
| Rest of MarylandMaryland | $134.63 | — |
| Rest of MaineMaine | $122.66 | — |
| Southern Maine, MEMaine | $131.31 | — |
| Detroit, MIMichigan | $130.62 | — |
| Rest of MichiganMichigan | $122.99 | — |
| MinnesotaMinnesota | $135.15 | — |
| Metropolitan Kansas City, MOMissouri | $125.80 | — |
| Metropolitan St. Louis, MOMissouri | $127.44 | — |
| Rest of MissouriMissouri | $116.43 | — |
| MississippiMississippi | $115.76 | — |
| MontanaMontana | $133.26 | — |
| North CarolinaNorth Carolina | $124.28 | — |
| North DakotaNorth Dakota | $131.88 | — |
| NebraskaNebraska | $122.45 | — |
| New HampshireNew Hampshire | $137.96 | — |
| Northern New JerseyNew Jersey | $153.47 | — |
| Rest of New JerseyNew Jersey | $145.06 | — |
| New MexicoNew Mexico | $123.65 | — |
| NevadaNevada | $133.00 | — |
| NYC suburbs and Long Island, NYNew York | $158.85 | — |
| Poughkeepsie and northern NYC suburbs, NYNew York | $145.73 | — |
| Queens, NYNew York | $157.03 | — |
| Rest of New YorkNew York | $126.50 | — |
| OhioOhio | $122.71 | — |
| OklahomaOklahoma | $119.74 | — |
| Portland, OROregon | $146.32 | — |
| Rest of OregonOregon | $132.09 | — |
| Metropolitan Philadelphia, PAPennsylvania | $138.87 | — |
| Rest of PennsylvaniaPennsylvania | $123.17 | — |
| Rhode IslandRhode Island | $137.21 | — |
| South CarolinaSouth Carolina | $123.68 | — |
| South DakotaSouth Dakota | $131.72 | — |
| TennesseeTennessee | $121.12 | — |
| Austin, TXTexas | $140.07 | — |
| Beaumont, TXTexas | $122.16 | — |
| Brazoria, TXTexas | $131.74 | — |
| Dallas, TXTexas | $132.54 | — |
| Fort Worth, TXTexas | $131.35 | — |
| Galveston, TXTexas | $132.09 | — |
| Houston, TXTexas | $133.37 | — |
| Rest of TexasTexas | $126.84 | — |
| UtahUtah | $125.74 | — |
| VirginiaVirginia | $130.52 | — |
| Virgin Islands, VIUnited States Virgin Islands | $134.57 | — |
| VermontVermont | $130.90 | — |
| Rest of WashingtonWashington | $139.28 | — |
| King County, WAWashington | $160.91 | — |
| WisconsinWisconsin | $126.55 | — |
| West VirginiaWest Virginia | $118.35 | — |
| WyomingWyoming | $132.66 | — |
96413 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$114.99
$165.49
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $144.80 | 1 |
| AL | $117.06 | 1 |
| AR | $114.99 | 1 |
| AZ | $129.16 | 1 |
| CA | $144.02–$186.95 | 29 |
| CO | $140.65 | 1 |
| CT | $143.31 | 1 |
| DC | $155.68 | 1 |
| DE | $131.62 | 1 |
| FL | $129.10–$141.83 | 3 |
| GA | $120.59–$135.71 | 2 |
| GU | $148.94 | 1 |
| HI | $148.94 | 1 |
| IA | $121.53 | 1 |
| ID | $122.31 | 1 |
| IL | $124.01–$138.42 | 4 |
| IN | $123.19 | 1 |
| KS | $120.44 | 1 |
| KY | $119.58 | 1 |
| LA | $119.19–$126.41 | 2 |
| MA | $139.39–$156.98 | 2 |
| MD | $134.63–$155.68 | 3 |
| ME | $122.66–$131.31 | 2 |
| MI | $122.99–$130.62 | 2 |
| MN | $135.15 | 1 |
| MO | $116.43–$127.44 | 3 |
| MS | $115.76 | 1 |
| MT | $133.26 | 1 |
| NC | $124.28 | 1 |
| ND | $131.88 | 1 |
| NE | $122.45 | 1 |
| NH | $137.96 | 1 |
| NJ | $145.06–$153.47 | 2 |
| NM | $123.65 | 1 |
| NV | $133.00 | 1 |
| NY | $126.50–$158.85 | 5 |
| OH | $122.71 | 1 |
| OK | $119.74 | 1 |
| OR | $132.09–$146.32 | 2 |
| PA | $123.17–$138.87 | 2 |
| PR | $134.57 | 1 |
| RI | $137.21 | 1 |
| SC | $123.68 | 1 |
| SD | $131.72 | 1 |
| TN | $121.12 | 1 |
| TX | $122.16–$140.07 | 8 |
| UT | $125.74 | 1 |
| VA | $130.52–$155.68 | 2 |
| VI | $134.57 | 1 |
| VT | $130.90 | 1 |
| WA | $139.28–$160.91 | 2 |
| WI | $126.55 | 1 |
| WV | $118.35 | 1 |
| WY | $132.66 | 1 |
How the 96413 rate is calculated
Each of 96413’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · 96413
RVUs × geographic indexes × conversion factor
Work0.28
0.28 RVUs× 1.000 GPCI
Practice expense3.64
3.64 RVUs× 1.000 GPCI
Malpractice0.07
0.07 RVUs× 1.000 GPCI
Adjusted RVUs
3.9900
Conversion factor
$33.4009
Medicare rate
$133.27
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
The exact Puerto Rico inputs and CMS source lines
PPRRVU2026_Oct_nonQPP.csv
12,801
- Code
- 96413
- Physician work
- 0.28
- Practice expense
- 3.64
- Malpractice
- 0.07
GPCI2026.csv
91
- Locality
- Puerto Rico
- Physician work
- 1.000
- Practice expense
- 1.011
- Malpractice
- 0.985
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.28 | × 1.000 | 0.2800 |
| Practice expense | 3.64 | × 1.011 | 3.6800 |
| Malpractice | 0.07 | × 0.985 | 0.0690 |
| Total RVUs | 4.0290 | ||
| Conversion factor | × 33.4009 | ||
Office rate, Puerto Rico$134.57
Office: (0.28 × 1 + 3.64 × 1.011 + 0.07 × 0.985) × $33.4009 = $134.57
Payment rules and modifiers for 96413
The CMS indicators that decide how 96413 is paid alongside other services.
CMS payment indicators · 96413
Chemo IV infusion, initial drug, first hour
| Rule | CMS value | What it means |
|---|---|---|
| Global period | XXX | The global surgery concept doesn’t apply. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 5 | Incident-to service. |
How 96413 has changed in Puerto Rico
96413 · Office / nonfacility
$134.57
Effective 2026-10-01
The base rate is $14.49 higher than on 2025-10-01, moving from $120.08 to $134.57 (12.1%).
It is unchanged from the immediately preceding available release, effective 2026-07-01.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2026
RVU26A
$120.08changed to$134.57
- Conversion factor 32.3465 changed to 33.4009
- Practice expense RVU 3.35 changed to 3.64
- Malpractice RVU 0.06 changed to 0.07
- Practice expense GPCI 1.007 changed to 1.011
- Malpractice GPCI 0.982 changed to 0.985
Held through RVU26B, RVU26C, RVU26D.
January 1, 2025
RVU25A
$129.94changed to$120.08
- Conversion factor 33.2875 changed to 32.3465
- Practice expense RVU 3.53 changed to 3.35
- Malpractice RVU 0.07 changed to 0.06
Held through RVU25B, RVU25C, RVU25D.
March 9, 2024
RVU24AR
$127.82changed to$129.94
- Conversion factor 32.7442 changed to 33.2875
Held through RVU24B, RVU24C, RVU24D.
January 1, 2024
RVU24A
$133.08changed to$127.82
- Conversion factor 33.8872 changed to 32.7442
- Practice expense RVU 3.55 changed to 3.53
- Practice expense GPCI 1.008 changed to 1.007
- Malpractice GPCI 0.984 changed to 0.982
October 1, 2023
RVU23D
$132.16changed to$133.08
- Practice expense GPCI 1.000 changed to 1.008
- Malpractice GPCI 1.000 changed to 0.984
January 1, 2023
RVU23A
$141.13changed to$132.16
- Conversion factor 34.6062 changed to 33.8872
- Practice expense RVU 3.68 changed to 3.55
- Malpractice RVU 0.09 changed to 0.07
- Practice expense GPCI 1.008 changed to 1.000
- Malpractice GPCI 0.986 changed to 1.000
Held through RVU23B, RVU23C.
January 1, 2022
RVU22A
$149.33changed to$141.13
- Conversion factor 34.8931 changed to 34.6062
- Practice expense RVU 3.88 changed to 3.68
Held through RVU22B, RVU22C, RVU22D.
January 1, 2021
RVU21A
$143.55changed to$149.33
- Conversion factor 36.0896 changed to 34.8931
- Practice expense RVU 3.58 changed to 3.88
- Malpractice GPCI 0.988 changed to 0.986
Held through RVU21B, RVU21C, RVU21D.
January 1, 2020
RVU20A
$143.96changed to$143.55
- Conversion factor 36.0391 changed to 36.0896
- Practice expense RVU 3.61 changed to 3.58
- Malpractice RVU 0.08 changed to 0.09
- Practice expense GPCI 1.007 changed to 1.008
- Malpractice GPCI 0.990 changed to 0.988
Held through RVU20B, RVU20C, RVU20D.
January 1, 2019
RVU19A
$145.61changed to$143.96
- Conversion factor 35.9996 changed to 36.0391
- Practice expense RVU 3.66 changed to 3.61
Held through RVU19B, RVU19C, RVU19D.
January 1, 2018
RVU18AR1
$120.34changed to$145.61
- Conversion factor 35.8887 changed to 35.9996
- Practice expense RVU 3.53 changed to 3.66
- Practice expense GPCI 0.856 changed to 1.007
- Malpractice GPCI 0.642 changed to 0.990
Held through RVU18B, RVU18C, RVU18D.
January 1, 2017
RVU17A
$97.95changed to$120.34
- Conversion factor 35.8043 changed to 35.8887
- Practice expense RVU 3.45 changed to 3.53
- Practice expense GPCI 0.705 changed to 0.856
- Malpractice GPCI 0.293 changed to 0.642
Held through RVU17B, RVU17C, RVU17D.
January 1, 2016
RVU16A
$98.20changed to$97.95
- Conversion factor 35.9335 changed to 35.8043
- Malpractice RVU 0.07 changed to 0.08
Held through RVU16B, RVU16C, RVU16D.
July 1, 2015
RVU15C
$97.71changed to$98.20
- Conversion factor 35.7547 changed to 35.9335
Held through RVU15D.
January 1, 2015
RVU15A
$94.55changed to$97.71
- Conversion factor 35.8228 changed to 35.7547
- Practice expense RVU 3.39 changed to 3.45
- Malpractice RVU 0.05 changed to 0.07
- Practice expense GPCI 0.692 changed to 0.705
- Malpractice GPCI 0.271 changed to 0.293
Held through RVU15B.
January 1, 2014
RVU14A
$99.45changed to$94.55
- Conversion factor 34.0230 changed to 35.8228
- Practice expense RVU 3.88 changed to 3.39
- Practice expense GPCI 0.678 changed to 0.692
- Malpractice GPCI 0.249 changed to 0.271
Held through RVU14B, RVU14C, RVU14D.
January 1, 2013
RVU13AR
Earliest loaded release: $99.45
Held through RVU13B, RVU13C, RVU13D.
| Effective from | Office | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | $134.57 | Not available in this setting | RVU26D |
| 2026-07-01 | $134.57 | Not available in this setting | RVU26C |
| 2026-04-01 | $134.57 | Not available in this setting | RVU26B |
| 2026-01-01 | $134.57 | Not available in this setting | RVU26A |
| 2025-10-01 | $120.08 | Not available in this setting | RVU25D |
| 2025-07-01 | $120.08 | Not available in this setting | RVU25C |
| 2025-04-01 | $120.08 | Not available in this setting | RVU25B |
| 2025-01-01 | $120.08 | Not available in this setting | RVU25A |
| 2024-10-01 | $129.94 | Not available in this setting | RVU24D |
| 2024-07-01 | $129.94 | Not available in this setting | RVU24C |
| 2024-04-01 | $129.94 | Not available in this setting | RVU24B |
| 2024-03-09 | $129.94 | Not available in this setting | RVU24AR |
| 2024-01-01 | $127.82 | Not available in this setting | RVU24A |
| 2023-10-01 | $133.08 | Not available in this setting | RVU23D |
| 2023-07-01 | $132.16 | Not available in this setting | RVU23C |
| 2023-04-01 | $132.16 | Not available in this setting | RVU23B |
| 2023-01-01 | $132.16 | Not available in this setting | RVU23A |
| 2022-10-01 | $141.13 | Not available in this setting | RVU22D |
| 2022-07-01 | $141.13 | Not available in this setting | RVU22C |
| 2022-04-01 | $141.13 | Not available in this setting | RVU22B |
| 2022-01-01 | $141.13 | Not available in this setting | RVU22A |
| 2021-10-01 | $149.33 | Not available in this setting | RVU21D |
| 2021-07-01 | $149.33 | Not available in this setting | RVU21C |
| 2021-04-01 | $149.33 | Not available in this setting | RVU21B |
| 2021-01-01 | $149.33 | Not available in this setting | RVU21A |
| 2020-10-01 | $143.55 | Not available in this setting | RVU20D |
| 2020-07-01 | $143.55 | Not available in this setting | RVU20C |
| 2020-04-01 | $143.55 | Not available in this setting | RVU20B |
| 2020-01-01 | $143.55 | Not available in this setting | RVU20A |
| 2019-10-01 | $143.96 | Not available in this setting | RVU19D |
| 2019-07-01 | $143.96 | Not available in this setting | RVU19C |
| 2019-04-01 | $143.96 | Not available in this setting | RVU19B |
| 2019-01-01 | $143.96 | Not available in this setting | RVU19A |
| 2018-10-01 | $145.61 | Not available in this setting | RVU18D |
| 2018-07-01 | $145.61 | Not available in this setting | RVU18C |
| 2018-04-01 | $145.61 | Not available in this setting | RVU18B |
| 2018-01-01 | $145.61 | Not available in this setting | RVU18AR1 |
| 2017-10-01 | $120.34 | Not available in this setting | RVU17D |
| 2017-07-01 | $120.34 | Not available in this setting | RVU17C |
| 2017-04-01 | $120.34 | Not available in this setting | RVU17B |
| 2017-01-01 | $120.34 | Not available in this setting | RVU17A |
| 2016-10-01 | $97.95 | Not available in this setting | RVU16D |
| 2016-07-01 | $97.95 | Not available in this setting | RVU16C |
| 2016-04-01 | $97.95 | Not available in this setting | RVU16B |
| 2016-01-01 | $97.95 | Not available in this setting | RVU16A |
| 2015-10-01 | $98.20 | Not available in this setting | RVU15D |
| 2015-07-01 | $98.20 | Not available in this setting | RVU15C |
| 2015-04-01 | $97.71 | Not available in this setting | RVU15B |
| 2015-01-01 | $97.71 | Not available in this setting | RVU15A |
| 2014-10-01 | $94.55 | Not available in this setting | RVU14D |
| 2014-07-01 | $94.55 | Not available in this setting | RVU14C |
| 2014-04-01 | $94.55 | Not available in this setting | RVU14B |
| 2014-01-01 | $94.55 | Not available in this setting | RVU14A |
| 2013-10-01 | $99.45 | Not available in this setting | RVU13D |
| 2013-07-01 | $99.45 | Not available in this setting | RVU13C |
| 2013-04-01 | $99.45 | Not available in this setting | RVU13B |
| 2013-01-01 | $99.45 | Not available in this setting | RVU13AR |
Where the Puerto Rico rate applies
Puerto Rico is a Medicare payment area, not a city. Our Census mapping connects it to 292 cities and communities in Puerto Rico. Some span more than one payment area; confirm with the service ZIP.
- Aceitunas
- Adjuntas
- Aguada
- Aguadilla
- Aguas Buenas
- Aguas Claras
- Aguilita
- Aibonito
96413 billing questions
How long must the infusion run to report 96413 instead of a push code?
The infusion must last more than 15 minutes. If the drug runs for 15 minutes or less, report 96409 for an antineoplastic IV push.
When is 96415 added for extra time?
Add 96415 for each additional hour of the same infusion once the infusion exceeds 90 minutes. An infusion lasting exactly 90 minutes supports 96413 alone.
Can 96413 be billed more than once on the same day?
Report one initial administration service per encounter unless separate medically necessary IV sites support distinct initial services. Append modifier 59 or, when accepted, XS to the distinct service and document the separate sites.
How are antiemetic premedications and hydration reported with chemotherapy?
A separately administered antiemetic may support 96375 for an IV push or 96367 for a sequential infusion. Medically necessary hydration may support 96361 when its time is separately documented, exceeds 30 minutes, and is not concurrent with the drug infusion.
Is a same-day E/M visit separately billable with 96413?
Yes, when the clinician performs a significant, separately identifiable evaluation beyond the routine pre-infusion assessment; append modifier 25 to the E/M code. Routine nursing checks and vital signs are part of the administration service.
Does 96413 include the chemotherapy drug itself?
No. Report a separately payable drug with its appropriate HCPCS code, often a J code, using units based on the administered dose and documenting any reportable waste.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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