HCPCS code A2021: Wound matrix, neomatrix, per square centimeter2026 Medicare rate & RVUs in Michigan
Report A2021 for Neomatrix wound matrix supplied by square centimeter with the primary wound application procedure for which it is used.
Medicare pays $116.19–$122.80 for A2021 in the office in Michigan, from Rest of Michigan to Detroit, MI. Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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On this page 9 sections
What A2021 covers
A2021 identifies Neomatrix wound matrix by the area supplied for wound treatment. Wound-care clinicians and surgeons may use the matrix in outpatient wound clinics or surgical settings as part of treatment for a wound. The product line is distinct from the clinician’s work to prepare the wound and apply the material; those services are reported under the applicable procedure code.
Report the product in square-centimeter units and pair it with the primary procedure for the wound application. Documentation should identify Neomatrix, the treated wound site, the area covered, and the associated application procedure. CMS classifies A2021 as an add-on code: it is billed only with a primary procedure, and its payment falls within that procedure’s global period. CMS also classifies it as technical-component-only; a separate code covers interpretation.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where A2021 pays more and less in Michigan
| Payment locality | Office | Facility |
|---|---|---|
| Detroit, MI | $122.80 | Unavailable |
| Rest of Michigan | $116.19 | Unavailable |
How the A2021 rate is calculated
Each of A2021’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · A2021
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for A2021
The CMS indicators that decide how A2021 is paid alongside other services.
CMS payment indicators · A2021
Wound matrix, neomatrix, per square centimeter
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
A2021 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- 15271Skin substitute graftFirst 25 cm², trunk/limbs
- 15271 reports the primary wound application procedure for its anatomic-site group; A2021 identifies the Neomatrix product used with that procedure.
- 15273Skin substitute graftLarge trunk or limb wound area
- 15273 is a primary application procedure for a different anatomic-site group. Choose the applicable application code by site and report A2021 for Neomatrix product.
- A2015Wound matrixPhoenix, per square centimeter
- A2015 identifies Phoenix wound matrix, while A2021 identifies Neomatrix. Select the product code that matches the material supplied.
A2021 billing questions
How is A2021 different from the wound application procedure?
A2021 reports the Neomatrix product by area. Report the applicable primary procedure separately for the wound application.
Can A2021 be billed by itself?
No. CMS identifies A2021 as an add-on code that must be billed with a primary procedure.
What documentation supports the units?
Document that Neomatrix was used, the wound site, and the area covered in square centimeters, along with the associated primary procedure.
Does the global period affect payment for A2021?
Yes. CMS states that A2021 is paid within the global period of the primary procedure.
What does technical-component-only mean for this code?
CMS classifies A2021 as technical-component-only and specifies that a separate code covers interpretation.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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