FeeBase
Log inGet started
Menu

HCPCS code A2021: Wound matrix, neomatrix, per square centimeter2026 Medicare rate & RVUs

Report A2021 for Neomatrix wound matrix supplied by square centimeter with the primary wound application procedure for which it is used.

CMS RVU26DEffective Oct 1, 2026109 payment localities1K Medicare services in 2024

Medicare pays $127.26 for A2021 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · A2021

Wound matrix, neomatrix, per square centimeter

Office or facility?

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for A2021 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What A2021 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What A2021 covers

A2021 identifies Neomatrix wound matrix by the area supplied for wound treatment. Wound-care clinicians and surgeons may use the matrix in outpatient wound clinics or surgical settings as part of treatment for a wound. The product line is distinct from the clinician’s work to prepare the wound and apply the material; those services are reported under the applicable procedure code.

Report the product in square-centimeter units and pair it with the primary procedure for the wound application. Documentation should identify Neomatrix, the treated wound site, the area covered, and the associated application procedure. CMS classifies A2021 as an add-on code: it is billed only with a primary procedure, and its payment falls within that procedure’s global period. CMS also classifies it as technical-component-only; a separate code covers interpretation.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where A2021 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

A2021 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta, GA$129.29Unavailable
Austin, TX$134.64Unavailable
Bakersfield, CA$139.47Unavailable
Baltimore area, MD$136.55Unavailable
Beaumont, TX$115.80Unavailable
Brazoria, TX$126.11Unavailable

A2021 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
A2021 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the A2021 rate is calculated

Each of A2021’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · A2021

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for A2021

The CMS indicators that decide how A2021 is paid alongside other services.

CMS payment indicators · A2021

Wound matrix, neomatrix, per square centimeter

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

A2021 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • A2021

    Wound matrix, neomatrix, per square centimeter0 wRVU

    $127.26

  • 15271

    Skin substitute graft, first 25 cm², trunk/limbs1.46 wRVU

    $157.99+$30.73

  • 15273

    Skin substitute graft, large trunk or limb wound area3.41 wRVU

    $321.98+$194.72

  • A2015

    Wound matrix, phoenix, per square centimeter0 wRVU

    $127.26+$0.00

How to choose

15271Skin substitute graftFirst 25 cm², trunk/limbs
15271 reports the primary wound application procedure for its anatomic-site group; A2021 identifies the Neomatrix product used with that procedure.
15273Skin substitute graftLarge trunk or limb wound area
15273 is a primary application procedure for a different anatomic-site group. Choose the applicable application code by site and report A2021 for Neomatrix product.
A2015Wound matrixPhoenix, per square centimeter
A2015 identifies Phoenix wound matrix, while A2021 identifies Neomatrix. Select the product code that matches the material supplied.

Codes related to A2021

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to A2021
CodeHow it relatesNational office range
Primary code
15271Skin substitute graft, first 25 cm², trunk/limbsPrimary wound application procedure for the applicable anatomic site and wound area.$140.17–$205.27
15273Skin substitute graft, large trunk or limb wound areaPrimary wound application procedure for a different anatomic-site group.$285.52–$407.73
Used instead
A2015Wound matrix, phoenix, per square centimeterPhoenix wound matrix is a separately identified wound product billed by area.$109.31–$183.51
A2022Wound matrix, innovabrn/Innovamatx XL, per square centimeterInnovabrn/Innovamatx XL is a separately identified wound product billed by area.$109.31–$183.51
A2027Matriderm, per square centimeterMatriderm is a separately identified wound product billed by area.$109.31–$183.51

A2021 billing questions

How is A2021 different from the wound application procedure?

A2021 reports the Neomatrix product by area. Report the applicable primary procedure separately for the wound application.

Can A2021 be billed by itself?

No. CMS identifies A2021 as an add-on code that must be billed with a primary procedure.

What documentation supports the units?

Document that Neomatrix was used, the wound site, and the area covered in square centimeters, along with the associated primary procedure.

Does the global period affect payment for A2021?

Yes. CMS states that A2021 is paid within the global period of the primary procedure.

What does technical-component-only mean for this code?

CMS classifies A2021 as technical-component-only and specifies that a separate code covers interpretation.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for A2021PPRRVU2026_Oct_nonQPP.csv, line 13,242 (RVU26D)

Open CMS sourceHow we calculate rates

Did this answer your question about what A2021 pays?

Tell us what you were actually trying to work out. We’ll answer you directly, or build the page that does.

Fee sheets · Coming soon

Put A2021 and the rest of your codes on one sheet

Your codes at your locality, with payer contracts beside Medicare.

Join the waitlist