HCPCS code J0775: Collagenase injection, per 0.01 mg2026 Medicare rate & RVUs

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What J0775 covers

Collagenase clostridium histolyticum (Xiaflex) is an injectable enzyme used to treat Dupuytren contracture by targeting a palpable cord in the hand and Peyronie disease by targeting a penile plaque. Hand and orthopedic specialists and urologists administer it in the relevant clinical setting. J0775 identifies the drug quantity; CPT procedure codes describe the injection service.

CMS assigns J0775 status E, excluding it from the physician fee schedule. When Medicare covers the drug, it is a Part B drug generally priced through CMS quarterly Average Sales Price drug pricing files, and coverage is left to the Medicare contractor's judgment. One unit represents 0.01 mg; for example, 0.58 mg is 58 units. Report units from the documented amount administered.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where J0775 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

J0775 rates by state

Office rate range in each state. Select a state to see its payment localities.

How the J0775 rate is calculated

Each of J0775’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for J0775

J0775 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

J0775 compared with similar codes

How to choose

20527Palmar cord injectionEnzyme injection

Use 20527 to describe enzyme injection into a palmar fascial cord. J0775 identifies the collagenase drug quantity, not the procedure.

54200Plaque injectionPeyronie's disease

Use 54200 to describe injection treatment of a Peyronie plaque. J0775 identifies the collagenase drug used during that treatment.

26341Cord manipulationAfter enzyme injection

CPT 26341 describes manipulation of a finger joint following collagenase treatment for Dupuytren contracture; it is not the drug or its injection procedure.

Codes related to J0775

Related codes aren’t interchangeable: bill the code that matches the service performed.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates