HCPCS code J2778: Ranibizumab injection, per 0.1 mg2026 Medicare rate & RVUs

Ranibizumab is an intravitreal anti-VEGF drug reported in 0.1 mg units for retinal conditions such as neovascular AMD and diabetic macular edema.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare rate · J2778

Ranibizumab injection, per 0.1 mg

Office or facility?

Work RVUs
0
Total RVUs
0.00
Global days
XXX

National rate · 2026

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Not priced in the facility setting.

See every locality for J2778 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What J2778 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What J2778 covers

Ranibizumab is an anti-VEGF medicine injected into the vitreous of the eye to treat retinal disease. Ophthalmologists, often retina specialists, administer it in outpatient eye-care settings for conditions including neovascular age-related macular degeneration, macular edema after retinal vein occlusion, diabetic macular edema, and diabetic retinopathy. The drug is reported separately from the service of injecting it.

J2778 represents each 0.1 mg of ranibizumab; for example, a 0.5 mg dose equals five units. The CMS physician fee schedule status is E, meaning the drug is excluded from that fee schedule. When Medicare covers it, payment generally follows the Part B drug method using CMS quarterly Average Sales Price drug pricing files. Coverage is left to the Medicare contractor’s judgment.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where J2778 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

J2778 office and facility rates by payment locality
Payment localityOfficeFacility
AlabamaUnavailableUnavailable
AlaskaUnavailableUnavailable
ArizonaUnavailableUnavailable
ArkansasUnavailableUnavailable
Atlanta, GAUnavailableUnavailable
Austin, TXUnavailableUnavailable
Bakersfield, CAUnavailableUnavailable
Baltimore area, MDUnavailableUnavailable
Beaumont, TXUnavailableUnavailable
Brazoria, TXUnavailableUnavailable

J2778 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

View every state and territory as a table
J2778 office rate range by state
State / territoryOffice rate rangeLocalities
AKNo published base rate1
ALNo published base rate1
ARNo published base rate1
AZNo published base rate1
CANo published base rate29
CONo published base rate1
CTNo published base rate1
DCNo published base rate1
DENo published base rate1
FLNo published base rate3
GANo published base rate2
GUNo published base rate1
HINo published base rate1
IANo published base rate1
IDNo published base rate1
ILNo published base rate4
INNo published base rate1
KSNo published base rate1
KYNo published base rate1
LANo published base rate2
MANo published base rate2
MDNo published base rate3
MENo published base rate2
MINo published base rate2
MNNo published base rate1
MONo published base rate3
MSNo published base rate1
MTNo published base rate1
NCNo published base rate1
NDNo published base rate1
NENo published base rate1
NHNo published base rate1
NJNo published base rate2
NMNo published base rate1
NVNo published base rate1
NYNo published base rate5
OHNo published base rate1
OKNo published base rate1
ORNo published base rate2
PANo published base rate2
PRNo published base rate1
RINo published base rate1
SCNo published base rate1
SDNo published base rate1
TNNo published base rate1
TXNo published base rate8
UTNo published base rate1
VANo published base rate2
VINo published base rate1
VTNo published base rate1
WANo published base rate2
WINo published base rate1
WVNo published base rate1
WYNo published base rate1

How the J2778 rate is calculated

Each of J2778’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · J2778

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense0.00

0.00 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

0.0000

Conversion factor

$33.4009

Medicare rate

$0.00

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for J2778

J2778 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · J2778

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

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J2778 isn’t priced in this setting.

J2778 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • J2778

    Ranibizumab injection, per 0.1 mg0 wRVU

    Not priced

  • 67028

    Intravitreal injection, medication delivered into vitreous cavity1.4 wRVU

    $114.23

  • J2777

    Faricimab injection, per 0.1 mg0 wRVU

    Not priced

  • J2779

    Susvimo ranibizumab, per 0.1 mg0 wRVU

    Not priced

How to choose

67028Intravitreal injectionMedication delivered into vitreous cavity
67028 reports the procedure of injecting a pharmacologic agent into the vitreous. J2778 reports the ranibizumab drug quantity.
J2777Faricimab injectionPer 0.1 mg
J2777 is for faricimab-svoa; J2778 is for ranibizumab. Select the code for the drug administered.
J2779Susvimo ranibizumabPer 0.1 mg
J2779 identifies ranibizumab associated with the Susvimo delivery system. J2778 reports ranibizumab in 0.1 mg units.

J2778 billing questions

What does one J2778 unit represent?

One unit represents 0.1 mg of ranibizumab. A 0.5 mg dose equals five units.

Does J2778 include the intravitreal injection?

No. J2778 identifies the ranibizumab drug quantity; CPT 67028 identifies the intravitreal injection service. They are commonly reported for the same encounter.

How does Medicare treat J2778?

CMS assigns status E, excluding J2778 from the physician fee schedule. When covered, Medicare generally pays it as a Part B drug through the quarterly ASP pricing method, with coverage left to the Medicare contractor’s judgment.

How is J2778 different from J2777?

J2778 reports ranibizumab, while J2777 reports faricimab-svoa. Both are intravitreal retinal drugs, but the code follows the specific drug administered.

When would J2779 be used instead?

J2779 identifies ranibizumab associated with the Susvimo delivery system. J2778 is the code for ranibizumab reported by 0.1 mg for injection.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

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