HCPCS code J2997: Alteplase injection, per 1 mg2026 Medicare rate & RVUs in Missouri
Reports recombinant alteplase furnished for thrombolytic treatment or vascular-access device declotting, with each HCPCS unit representing 1 mg.
CMS doesn’t publish an office rate for J2997 in Missouri.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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On this page 9 sections
What J2997 covers
Alteplase is a recombinant clot-dissolving drug used intravenously for conditions such as acute ischemic stroke and pulmonary embolism. It may also be instilled into an occluded vascular access device to restore patency. Hospitals and other entities furnishing the drug may report this HCPCS drug code; a related procedure code, when applicable, identifies the service rather than the drug itself.
CMS assigns J2997 physician fee schedule status E, excluding it from the physician fee schedule. When Medicare covers the drug, it is a Part B drug generally priced using CMS quarterly Average Sales Price drug pricing files; special Medicare coverage instructions apply. One HCPCS unit represents 1 mg of alteplase. Report units according to the amount of drug represented by the billed units, and distinguish the drug from any separately reported procedure.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where J2997 pays more and less in Missouri
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
| Payment locality | Office | Facility |
|---|---|---|
| Metropolitan Kansas City, MO | Unavailable | Unavailable |
| Metropolitan St. Louis, MO | Unavailable | Unavailable |
| Rest of Missouri | Unavailable | Unavailable |
How the J2997 rate is calculated
Each of J2997’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · J2997
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense0.00
0.00 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
0.0000
Conversion factor
$33.4009
Medicare rate
$0.00
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for J2997
J2997 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.
Place of service · J2997
Which rate does Medicare pay?
The POS code on the claim line (CMS-1500 box 24B).
POS 11 · non-facility rate · national
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J2997 isn’t priced in this setting.
J2997 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- J2993Reteplase injectionPer 18.1 mg
- J2993 identifies reteplase, not alteplase. Use J2997 when the drug furnished is alteplase.
- J2998Plasminogen injectionPer 1 mg
- J2998 identifies plasminogen, not alteplase. Choose the code for the drug furnished.
- 36593Device declotThrombolytic treatment
- CPT 36593 describes thrombolytic declotting of an implanted vascular access device or catheter; J2997 identifies the alteplase drug.
J2997 billing questions
How many milligrams does one J2997 unit represent?
One unit represents 1 mg of recombinant alteplase. Calculate units from the amount of alteplase represented on the claim.
How is J2997 different from J2998?
J2997 identifies alteplase; J2998 identifies plasminogen. Select the code for the drug furnished.
When is J2997 used with a catheter declotting procedure?
For thrombolytic declotting of an implanted vascular access device or catheter, CPT 36593 identifies the procedure, while J2997 identifies the alteplase drug.
Does Medicare pay J2997 under the physician fee schedule?
No. CMS assigns status E, excluding J2997 from the physician fee schedule. When covered, it is a Part B drug generally priced through CMS quarterly ASP drug pricing files.
What Medicare coverage instructions apply to J2997?
Special Medicare coverage instructions apply to J2997.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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