HCPCS code J2998: Plasminogen injection, per 1 mg2026 Medicare rate & RVUs in Louisiana

Reports intravenous human plasminogen-tvmh replacement therapy for type 1 congenital plasminogen deficiency, with each unit representing 1 mg.

CMS RVU26DEffective Oct 1, 20262 payment localities

CMS doesn’t publish an office rate for J2998 in Louisiana.

—Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Louisiana
  2. What J2998 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What J2998 covers

J2998 identifies human plasminogen-tvmh, a replacement product for patients with type 1 congenital plasminogen deficiency. The deficiency can cause abnormal lesions on mucous membranes, including the eyes. Treatment is administered by intravenous infusion under a clinician's direction. This product replaces deficient plasminogen; it is not a thrombolytic for acute clot management.

The HCPCS unit represents 1 mg, so report the total milligrams administered as the corresponding number of units. J2998 has physician fee schedule status E and is excluded from the physician fee schedule. When Medicare covers the drug, payment is made under another payment method; CMS identifies it as a Part B drug generally priced using quarterly ASP files. Coverage is left to the Medicare contractor's judgment. The drug code identifies the product quantity; CPT 96365 may identify the initial therapeutic infusion administration when applicable.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where J2998 pays more and less in Louisiana

J2998 office and facility rates by payment locality
Payment localityOfficeFacility
New Orleans, LAUnavailableUnavailable
Rest of LouisianaUnavailableUnavailable

How the J2998 rate is calculated

Each of J2998’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · J2998

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense0.00

0.00 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

0.0000

Conversion factor

$33.4009

Medicare rate

$0.00

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for J2998

J2998 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · J2998

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

—

J2998 isn’t priced in this setting.

J2998 compared with similar codes

Compare codes · National

J2998 vs J2997 vs J2993: Medicare rates

Office or facility?

  • J2998

    Plasminogen injection, per 1 mg0 wRVU

    Not priced

  • J2997

    Alteplase injection, per 1 mg0 wRVU

    Not priced

  • J2993

    Reteplase injection, per 18.1 mg0 wRVU

    Not priced

How to choose

J2997Alteplase injectionPer 1 mg
J2997 identifies alteplase, a thrombolytic drug. J2998 identifies human plasminogen-tvmh replacement therapy for congenital plasminogen deficiency.
J2993Reteplase injectionPer 18.1 mg
J2993 identifies reteplase, a thrombolytic drug; J2998 identifies human plasminogen-tvmh used for congenital plasminogen deficiency.

J2998 billing questions

What condition is this plasminogen product used to treat?

It is replacement therapy for type 1 congenital plasminogen deficiency. It is not the thrombolytic treatment represented by alteplase or reteplase codes.

How many units should be reported?

One J2998 unit represents 1 mg of human plasminogen-tvmh. Report units based on the total milligrams administered.

Does J2998 include the infusion service?

J2998 identifies the drug quantity. CPT 96365 may identify the initial therapeutic intravenous infusion administration when applicable.

How does Medicare classify payment for J2998?

CMS assigns status E, excluding the code from the physician fee schedule. When covered, the drug is a Part B drug generally priced through quarterly ASP files, and the Medicare contractor determines coverage.

What documentation supports the reported units?

Document the product administered and the total milligrams given so the reported quantity can be matched to the 1 mg unit definition.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

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