HCPCS code J3299: Xipere injection, per 1 mg2026 Medicare rate & RVUs in Illinois
Reports each 1 mg of Xipere triamcinolone used for suprachoroidal treatment of macular edema associated with uveitis.
CMS doesn’t publish an office rate for J3299 in Illinois.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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On this page 9 sections
What J3299 covers
Xipere is a triamcinolone acetonide suspension administered into the suprachoroidal space of the eye. Ophthalmologists, often retina specialists, use it to treat macular edema associated with uveitis. The drug is supplied for suprachoroidal use, a route distinct from intravitreal injection. Its administration is commonly reported with CPT 67516, the procedure code for suprachoroidal drug injection.
J3299 represents 1 mg of Xipere; the labeled 4 mg dose is reported as 4 units. CMS assigns this code physician fee schedule status E, meaning it is excluded from the physician fee schedule. When Medicare covers the drug, it is a Part B drug generally priced through CMS quarterly ASP drug pricing files. Coverage is left to the Medicare contractor's judgment, and a covered item is paid under another payment method rather than the physician fee schedule.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where J3299 pays more and less in Illinois
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
| Payment locality | Office | Facility |
|---|---|---|
| Chicago, IL | Unavailable | Unavailable |
| East St. Louis, IL | Unavailable | Unavailable |
| Rest of Illinois | Unavailable | Unavailable |
| Suburban Chicago, IL | Unavailable | Unavailable |
How the J3299 rate is calculated
Each of J3299’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · J3299
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense0.00
0.00 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
0.0000
Conversion factor
$33.4009
Medicare rate
$0.00
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for J3299
J3299 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.
Place of service · J3299
Which rate does Medicare pay?
The POS code on the claim line (CMS-1500 box 24B).
POS 11 · non-facility rate · national
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J3299 isn’t priced in this setting.
J3299 compared with similar codes
Compare codes · National
5 codes, side by side
How to choose
- J3300Triamcinolone injectionPreservative-free, per 1 mg
- J3300 identifies preservative-free triamcinolone by the milligram for intravitreal use. J3299 is specific to Xipere for suprachoroidal use.
- J3301Triamcinolone injectionPer 10 mg
- J3301 reports triamcinolone acetonide not otherwise specified in 10 mg units. J3299 identifies the specific Xipere product in 1 mg units.
- 67516Eye injectionSuprachoroidal route
- CPT 67516 reports the suprachoroidal injection procedure; J3299 reports the Xipere drug quantity administered.
- 67028Intravitreal injectionMedication delivered into vitreous cavity
- CPT 67028 is for intravitreal injection. CPT 67516 is the procedure code associated with suprachoroidal delivery of Xipere.
J3299 billing questions
What does one unit of J3299 represent?
One unit represents 1 mg of Xipere. The 4 mg dose is reported as 4 units.
Which administration code is associated with suprachoroidal delivery?
CPT 67516 describes injection of a pharmacologic agent into the suprachoroidal space and is commonly reported with the drug when applicable.
Is J3299 the same as the code for intravitreal triamcinolone?
No. J3299 identifies Xipere for suprachoroidal use; J3300 identifies preservative-free triamcinolone by the milligram for a different product and route.
How does Medicare treat payment and coverage for J3299?
CMS excludes J3299 from the physician fee schedule with status E. When covered, it is a Part B drug generally priced through quarterly ASP files, and the Medicare contractor determines coverage.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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