HCPCS code J3424: Hydroxocobalamin injection, intravenous, per 25 mg2026 Medicare rate & RVUs in Florida
Reports intravenous hydroxocobalamin, commonly used as an antidote for suspected cyanide poisoning, in units representing 25 mg of the drug.
CMS doesn’t publish an office rate for J3424 in Florida.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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On this page 9 sections
What J3424 covers
J3424 identifies hydroxocobalamin given intravenously, most notably as an antidote when cyanide poisoning is suspected. Emergency clinicians may administer it in an office-based emergency setting or hospital while treating a potentially life-threatening exposure. This high-dose intravenous use is distinct from hydroxocobalamin injections used for vitamin B12 replacement, which are generally given by a different route and billed under a different code.
Each billing unit represents 25 mg of hydroxocobalamin; divide the administered dose in milligrams by 25 to determine the units. CMS excludes this code from the physician fee schedule under status E. When Medicare covers the drug, payment is under another payment method; the HCPCS pricing method identifies it as a Part B drug generally priced from CMS quarterly ASP files. Coverage is left to the Medicare contractor’s judgment.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where J3424 pays more and less in Florida
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
| Payment locality | Office | Facility |
|---|---|---|
| Fort Lauderdale, FL | Unavailable | Unavailable |
| Miami, FL | Unavailable | Unavailable |
| Rest of Florida | Unavailable | Unavailable |
How the J3424 rate is calculated
Each of J3424’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · J3424
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense0.00
0.00 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
0.0000
Conversion factor
$33.4009
Medicare rate
$0.00
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for J3424
J3424 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.
Place of service · J3424
Which rate does Medicare pay?
The POS code on the claim line (CMS-1500 box 24B).
POS 11 · non-facility rate · national
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J3424 isn’t priced in this setting.
J3424 compared with similar codes
Compare codes · National
J3424 vs J3425 vs J3420: Medicare rates
How to choose
- J3425Hydroxocobalamin injectionPer 10 mcg
- Use J3424 for intravenous hydroxocobalamin per 25 mg; J3425 identifies intramuscular hydroxocobalamin per its own dose unit.
- J3420Vitamin B12 injectionUp to 1,000 mcg
- J3420 is a separate vitamin B12 injection code. J3424 identifies intravenous hydroxocobalamin, commonly used as a cyanide antidote.
J3424 billing questions
When should J3424 be used instead of J3425?
J3424 is for intravenous hydroxocobalamin billed per 25 mg. J3425 identifies intramuscular hydroxocobalamin with a different dose unit, so select the code that matches the drug’s route and amount.
How many units should be reported?
Report one unit for each 25 mg administered. For example, 100 mg equals four units.
Is J3424 paid under the physician fee schedule?
No. CMS assigns status E, excluding the code from the physician fee schedule. When Medicare covers the drug, it pays under another payment method; HCPCS pricing identifies it as a Part B drug generally priced through quarterly ASP files.
Does Medicare cover every use of J3424?
Coverage is left to the Medicare contractor’s judgment. The code is commonly associated with intravenous treatment of suspected cyanide poisoning.
Is J3424 the code for routine vitamin B12 replacement?
It identifies intravenous hydroxocobalamin per 25 mg, commonly used as a cyanide antidote. J3420 is a separate vitamin B12 injection code, and J3425 identifies intramuscular hydroxocobalamin.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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