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HCPCS code J3425: Hydroxocobalamin injection, per 10 mcg2026 Medicare rate & RVUs

Reports intramuscular hydroxocobalamin given for vitamin B12 replacement, with each billing unit representing 10 mcg of the drug.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare rate · J3425

Hydroxocobalamin injection, per 10 mcg

Office or facility?

Work RVUs
0
Total RVUs
0.00
Global days
XXX

National rate · 2026

—

Not priced in the facility setting.

See every locality for J3425 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What J3425 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What J3425 covers

This code identifies hydroxocobalamin administered by intramuscular injection, generally for vitamin B12 replacement, including treatment of B12 deficiency. Clinicians report the drug when they administer an intramuscular dose, including in office or outpatient care. It is distinct from hydroxocobalamin given intravenously and from other vitamin B12 products, even when the clinical purpose is similar.

CMS assigns status E, excluding the code from the physician fee schedule. When Medicare covers the item or service, payment is made under another method; HCPCS pricing identifies it as a Part B drug, generally priced through CMS quarterly Average Sales Price drug pricing files. Special Medicare coverage instructions apply. Each unit represents 10 mcg, so a documented 1,000 mcg dose corresponds to 100 units. Report units from the amount administered and retain documentation supporting the drug and dose.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where J3425 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

J3425 office and facility rates by payment locality
Payment localityOfficeFacility
AlabamaUnavailableUnavailable
AlaskaUnavailableUnavailable
ArizonaUnavailableUnavailable
ArkansasUnavailableUnavailable
Atlanta, GAUnavailableUnavailable
Austin, TXUnavailableUnavailable
Bakersfield, CAUnavailableUnavailable
Baltimore area, MDUnavailableUnavailable
Beaumont, TXUnavailableUnavailable
Brazoria, TXUnavailableUnavailable

J3425 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

View every state and territory as a table
J3425 office rate range by state
State / territoryOffice rate rangeLocalities
AKNo published base rate1
ALNo published base rate1
ARNo published base rate1
AZNo published base rate1
CANo published base rate29
CONo published base rate1
CTNo published base rate1
DCNo published base rate1
DENo published base rate1
FLNo published base rate3
GANo published base rate2
GUNo published base rate1
HINo published base rate1
IANo published base rate1
IDNo published base rate1
ILNo published base rate4
INNo published base rate1
KSNo published base rate1
KYNo published base rate1
LANo published base rate2
MANo published base rate2
MDNo published base rate3
MENo published base rate2
MINo published base rate2
MNNo published base rate1
MONo published base rate3
MSNo published base rate1
MTNo published base rate1
NCNo published base rate1
NDNo published base rate1
NENo published base rate1
NHNo published base rate1
NJNo published base rate2
NMNo published base rate1
NVNo published base rate1
NYNo published base rate5
OHNo published base rate1
OKNo published base rate1
ORNo published base rate2
PANo published base rate2
PRNo published base rate1
RINo published base rate1
SCNo published base rate1
SDNo published base rate1
TNNo published base rate1
TXNo published base rate8
UTNo published base rate1
VANo published base rate2
VINo published base rate1
VTNo published base rate1
WANo published base rate2
WINo published base rate1
WVNo published base rate1
WYNo published base rate1

How the J3425 rate is calculated

Each of J3425’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · J3425

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense0.00

0.00 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

0.0000

Conversion factor

$33.4009

Medicare rate

$0.00

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for J3425

J3425 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · J3425

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

—

J3425 isn’t priced in this setting.

J3425 compared with similar codes

Compare codes · National

J3425 vs J3424 vs J3420: Medicare rates

Office or facility?

  • J3425

    Hydroxocobalamin injection, per 10 mcg0 wRVU

    Not priced

  • J3424

    Hydroxocobalamin injection, intravenous, per 25 mg0 wRVU

    Not priced

  • J3420

    Vitamin B12 injection, up to 1,000 mcg0 wRVU

    Not priced

How to choose

J3424Hydroxocobalamin injectionIntravenous, per 25 mg
Use J3425 for intramuscular hydroxocobalamin per 10 mcg. J3424 identifies the intravenous route and a different dose basis.
J3420Vitamin B12 injectionUp to 1,000 mcg
J3420 is a separate vitamin B12 injection code associated with cyanocobalamin. J3425 identifies hydroxocobalamin administered intramuscularly.

Codes related to J3425

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to J3425
CodeHow it relatesNational office range
Same family
J3424Hydroxocobalamin injection, intravenous, per 25 mgIdentifies hydroxocobalamin by the intravenous route and a different dose basis.No office rate
Used instead
J3420Vitamin B12 injection, up to 1,000 mcgA separate vitamin B12 injection code associated with cyanocobalamin.No office rate

J3425 billing questions

How many units represent a 1,000 mcg dose?

Each unit represents 10 mcg, so 1,000 mcg corresponds to 100 units.

Should this code be used for intravenous hydroxocobalamin?

No. This code is for intramuscular hydroxocobalamin; J3424 identifies hydroxocobalamin administered intravenously.

How does this differ from J3420?

J3425 identifies hydroxocobalamin per 10 mcg. J3420 is a separate vitamin B12 injection code associated with cyanocobalamin, not hydroxocobalamin.

Does Medicare pay this code under the physician fee schedule?

No. CMS assigns status E, excluding it from the physician fee schedule. When covered, payment follows another method; CMS identifies it as a Part B drug generally priced through quarterly ASP files.

What should the administration record support?

Document the hydroxocobalamin product, intramuscular route, and amount administered so the reported units can be verified.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

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