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HCPCS code Q4105: Skin substitute, integra DRT or Omnigraft2026 Medicare rate & RVUs in Delaware

Reports Integra DRT or Omnigraft wound matrix supplied for application to a wound, such as a burn or diabetic foot ulcer.

CMS RVU26DEffective Oct 1, 2026One payment locality

In Delaware, Medicare pays $125.73 for Q4105 in the office.

$125.73Office (non-facility)
Not available in this settingHospital or facility
−1.2%vs the national office rate ($127.26)

Check a contract rate as a % of Medicare · Q4105 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4105 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Delaware
  2. What Q4105 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What Q4105 covers

Q4105 identifies the Integra dermal regeneration template product, including Omnigraft, supplied for wound coverage. The material is used in wound care, including burn treatment and, for Omnigraft, diabetic foot ulcer treatment. Plastic surgeons, wound-care clinicians, and podiatrists may use it in hospital outpatient departments, clinics, or other settings where a wound application procedure is performed. The product supply is distinct from the clinician’s work applying it.

Report Q4105 with the primary procedure used to apply the product, selecting that procedure for the wound’s site and treated area. Document the exact product, wound location and dimensions, amount supplied and applied, and the related application procedure. CMS classifies Q4105 as an add-on code: it is billed only with a primary procedure and paid within that procedure’s global period. CMS also classifies it as technical-component-only, with interpretation covered by a separate code.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Delaware compares for Q4105

Across 109 of 109 payment localities, the office rate for Q4105 runs from $109.31 in Arkansas to $183.51 in Santa Clara County, CA. Delaware pays $125.73. The RVUs are the same everywhere; the geographic indexes change the dollars.

Q4105 in Delaware vs other payment areas
  1. Delaware · this page$125.73
  2. Los Angeles, CA · California$150.55+$24.82
  3. Washington, DC area · District of Columbia$149.91+$24.18
  4. Miami, FL · Florida$132.47+$6.74
  5. Chicago, IL · Illinois$127.89+$2.16
  6. Manhattan, NY · New York$147.87+$22.14
  7. Alaska · Alaska$135.53+$9.80

Other areas in Delaware first, then benchmark localities. Bars start at $0.

Every other payment area

Q4105 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$111.35—
ArkansasArkansas$109.31—
ArizonaArizona$123.31—
Bakersfield, CACalifornia$139.47—
Chico, CACalifornia$139.47—
El Centro, CACalifornia$139.47—
Fresno, CACalifornia$139.47—
Hanford, CACalifornia$139.47—

Q4105 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4105 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

See Q4105 in every payment locality

How the Q4105 rate is calculated

Each of Q4105’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4105

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Delaware inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

18,205

Code
Q4105
Physician work
0.00
Practice expense
3.81
Malpractice
0.00

GPCI2026.csv

40

Locality
Delaware
Physician work
1.005
Practice expense
0.988
Malpractice
0.899
Office calculation for Q4105 in Delaware
ComponentRVULocality factorAdjusted
Physician work0.00× 1.0050.0000
Practice expense3.81× 0.9883.7643
Malpractice0.00× 0.8990.0000
Total RVUs3.7643
Conversion factor× 33.4009

Office rate, Delaware$125.73

Office: (0 × 1.005 + 3.81 × 0.988 + 0 × 0.899) × $33.4009 = $125.73

Open Q4105 in the RVU calculator

Payment rules and modifiers for Q4105

The CMS indicators that decide how Q4105 is paid alongside other services.

CMS payment indicators · Q4105

Skin substitute, integra DRT or Omnigraft

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Codes related to Q4105

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to Q4105
CodeHow it relatesOffice range, Delaware
Primary code
15271Skin substitute graft, first 25 cm², trunk/limbsPrimary application procedure for wounds on the trunk, arms, or legs.$156.30
15275Skin substitute, face and other specified sitesPrimary application procedure for sites including the feet.$158.82
Used instead
Q4104Wound matrix, integra BMWDA different Integra wound product; select according to the product supplied.$125.73
Q4108Wound matrix, integra MatrixAnother Integra product code, distinct from DRT or Omnigraft.$125.73
Q4101Skin substitute, apligraf, per square centimeterApligraf is a different skin substitute product used in wound care.$125.73

How Q4105 has changed in Delaware

Q4105 · Office / nonfacility

$125.73

Effective 2026-10-01

A rate is unavailable in one of these releases, so a change cannot be calculated.

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    No ratechanged to$125.73

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1, RVU18B, RVU18C, RVU18D, RVU19A, RVU19B, RVU19C, RVU19D, RVU20A, RVU20B, RVU20C, RVU20D, RVU21A, RVU21B, RVU21C, RVU21D, RVU22A, RVU22B, RVU22C, RVU22D, RVU23A, RVU23B, RVU23C, RVU23D, RVU24A, RVU24AR, RVU24B, RVU24C, RVU24D, RVU25A, RVU25B, RVU25C, RVU25D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$125.73Not available in this settingRVU26D
2026-07-01$125.73Not available in this settingRVU26C
2026-04-01$125.73Not available in this settingRVU26B
2026-01-01$125.73Not available in this settingRVU26A
2025-10-01Separate payment rules applySeparate payment rules applyRVU25D
2025-07-01Separate payment rules applySeparate payment rules applyRVU25C
2025-04-01Separate payment rules applySeparate payment rules applyRVU25B
2025-01-01Separate payment rules applySeparate payment rules applyRVU25A
2024-10-01Separate payment rules applySeparate payment rules applyRVU24D
2024-07-01Separate payment rules applySeparate payment rules applyRVU24C
2024-04-01Separate payment rules applySeparate payment rules applyRVU24B
2024-03-09Separate payment rules applySeparate payment rules applyRVU24AR
2024-01-01Separate payment rules applySeparate payment rules applyRVU24A
2023-10-01Separate payment rules applySeparate payment rules applyRVU23D
2023-07-01Separate payment rules applySeparate payment rules applyRVU23C
2023-04-01Separate payment rules applySeparate payment rules applyRVU23B
2023-01-01Separate payment rules applySeparate payment rules applyRVU23A
2022-10-01Separate payment rules applySeparate payment rules applyRVU22D
2022-07-01Separate payment rules applySeparate payment rules applyRVU22C
2022-04-01Separate payment rules applySeparate payment rules applyRVU22B
2022-01-01Separate payment rules applySeparate payment rules applyRVU22A
2021-10-01Separate payment rules applySeparate payment rules applyRVU21D
2021-07-01Separate payment rules applySeparate payment rules applyRVU21C
2021-04-01Separate payment rules applySeparate payment rules applyRVU21B
2021-01-01Separate payment rules applySeparate payment rules applyRVU21A
2020-10-01Separate payment rules applySeparate payment rules applyRVU20D
2020-07-01Separate payment rules applySeparate payment rules applyRVU20C
2020-04-01Separate payment rules applySeparate payment rules applyRVU20B
2020-01-01Separate payment rules applySeparate payment rules applyRVU20A
2019-10-01Separate payment rules applySeparate payment rules applyRVU19D
2019-07-01Separate payment rules applySeparate payment rules applyRVU19C
2019-04-01Separate payment rules applySeparate payment rules applyRVU19B
2019-01-01Separate payment rules applySeparate payment rules applyRVU19A
2018-10-01Separate payment rules applySeparate payment rules applyRVU18D
2018-07-01Separate payment rules applySeparate payment rules applyRVU18C
2018-04-01Separate payment rules applySeparate payment rules applyRVU18B
2018-01-01Separate payment rules applySeparate payment rules applyRVU18AR1
2017-10-01Separate payment rules applySeparate payment rules applyRVU17D
2017-07-01Separate payment rules applySeparate payment rules applyRVU17C
2017-04-01Separate payment rules applySeparate payment rules applyRVU17B
2017-01-01Separate payment rules applySeparate payment rules applyRVU17A
2016-10-01Separate payment rules applySeparate payment rules applyRVU16D
2016-07-01Separate payment rules applySeparate payment rules applyRVU16C
2016-04-01Separate payment rules applySeparate payment rules applyRVU16B
2016-01-01Separate payment rules applySeparate payment rules applyRVU16A
2015-10-01Separate payment rules applySeparate payment rules applyRVU15D
2015-07-01Separate payment rules applySeparate payment rules applyRVU15C
2015-04-01Separate payment rules applySeparate payment rules applyRVU15B
2015-01-01Separate payment rules applySeparate payment rules applyRVU15A
2014-10-01Separate payment rules applySeparate payment rules applyRVU14D
2014-07-01Separate payment rules applySeparate payment rules applyRVU14C
2014-04-01Separate payment rules applySeparate payment rules applyRVU14B
2014-01-01Separate payment rules applySeparate payment rules applyRVU14A
2013-10-01Separate payment rules applySeparate payment rules applyRVU13D
2013-07-01Separate payment rules applySeparate payment rules applyRVU13C
2013-04-01Separate payment rules applySeparate payment rules applyRVU13B
2013-01-01Separate payment rules applySeparate payment rules applyRVU13AR

Price Q4105 for an earlier date of service

Where the Delaware rate applies

Delaware is a Medicare payment area, not a city. Our Census mapping connects it to 79 cities and communities in Delaware. Some span more than one payment area; confirm with the service ZIP.

  • Arden
  • Ardencroft
  • Ardentown
  • Bear
  • Bellefonte
  • Bethany Beach
  • Bethel
  • Blades

Browse all communities in Delaware

Q4105 billing questions

How is Q4105 different from the Integra product codes Q4104 and Q4108?

Q4105 identifies Integra DRT or Omnigraft. Q4104 and Q4108 identify different Integra products, so verify the product actually supplied rather than choosing by manufacturer alone.

Can Q4105 be billed by itself?

No. CMS identifies it as an add-on code, so report it with the primary procedure used to apply the product.

Which application code should accompany Q4105?

Choose the primary wound-application procedure according to the wound site and treated area. For example, the application-code family includes 15271 for trunk, arm, or leg sites and 15275 for sites such as the feet.

What should the record support?

Document the exact Integra product, wound site and dimensions, amount supplied and applied, and the application procedure. The documentation should make clear that Q4105 represents the product rather than the application work.

How does the global-period rule affect Q4105?

Q4105 is billed with its primary procedure and paid within that procedure’s global period. It is not a stand-alone service line.

Does Q4105 include interpretation?

CMS classifies Q4105 as technical-component-only and assigns interpretation to a separate code. Q4105 itself identifies the product supply.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4105PPRRVU2026_Oct_nonQPP.csv, line 18,205 (RVU26D)
Geographic factors for DelawareGPCI2026.csv, line 40 (RVU26D)

Open CMS sourceHow we calculate rates

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