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HCPCS code Q4112: Cymetra injectable, per 1 cc2026 Medicare rate & RVUs

Reports one cubic centimeter of injectable Cymetra, a micronized human dermal matrix used for soft-tissue augmentation, including vocal-fold augmentation.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare rate · Q4112

Cymetra injectable, per 1 cc

Office or facility?

Work RVUs
0
Total RVUs
0.00
Global days
XXX

National rate · 2026

—

Not priced in the facility setting.

See every locality for Q4112 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What Q4112 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4112 covers

Cymetra is a micronized human dermal matrix supplied for injection as a soft-tissue augmenting material. Otolaryngologists may use it for vocal-fold augmentation, including treatment of glottic insufficiency; it may also be used for other soft-tissue augmentation procedures. The clinician reports the material separately from the procedure used to inject it, such as laryngoscopy with vocal-fold injection.

Q4112 represents 1 cc of Cymetra; report the number of units according to the volume used. Medicare assigns carrier-priced status: there is no national physician fee schedule payment, and the Medicare Administrative Contractor sets payment for each claim. The HCPCS pricing method places the code under the physician fee schedule, with coverage left to the contractor’s judgment. Q4112 is a technical-component-only code, with a separate code covering interpretation.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4112 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

Q4112 office and facility rates by payment locality
Payment localityOfficeFacility
AlabamaUnavailableUnavailable
AlaskaUnavailableUnavailable
ArizonaUnavailableUnavailable
ArkansasUnavailableUnavailable
Atlanta, GAUnavailableUnavailable
Austin, TXUnavailableUnavailable
Bakersfield, CAUnavailableUnavailable
Baltimore area, MDUnavailableUnavailable
Beaumont, TXUnavailableUnavailable
Brazoria, TXUnavailableUnavailable

Q4112 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

View every state and territory as a table
Q4112 office rate range by state
State / territoryOffice rate rangeLocalities
AKNo published base rate1
ALNo published base rate1
ARNo published base rate1
AZNo published base rate1
CANo published base rate29
CONo published base rate1
CTNo published base rate1
DCNo published base rate1
DENo published base rate1
FLNo published base rate3
GANo published base rate2
GUNo published base rate1
HINo published base rate1
IANo published base rate1
IDNo published base rate1
ILNo published base rate4
INNo published base rate1
KSNo published base rate1
KYNo published base rate1
LANo published base rate2
MANo published base rate2
MDNo published base rate3
MENo published base rate2
MINo published base rate2
MNNo published base rate1
MONo published base rate3
MSNo published base rate1
MTNo published base rate1
NCNo published base rate1
NDNo published base rate1
NENo published base rate1
NHNo published base rate1
NJNo published base rate2
NMNo published base rate1
NVNo published base rate1
NYNo published base rate5
OHNo published base rate1
OKNo published base rate1
ORNo published base rate2
PANo published base rate2
PRNo published base rate1
RINo published base rate1
SCNo published base rate1
SDNo published base rate1
TNNo published base rate1
TXNo published base rate8
UTNo published base rate1
VANo published base rate2
VINo published base rate1
VTNo published base rate1
WANo published base rate2
WINo published base rate1
WVNo published base rate1
WYNo published base rate1

How the Q4112 rate is calculated

Each of Q4112’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4112

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense0.00

0.00 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

0.0000

Conversion factor

$33.4009

Medicare rate

$0.00

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4112

The CMS indicators that decide how Q4112 is paid alongside other services.

CMS payment indicators · Q4112

Cymetra injectable, per 1 cc

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures9The concept doesn’t apply.
Bilateral (modifier 50)9The concept doesn’t apply.
Assistant at surgery (80/81/82/AS)9The concept doesn’t apply.
Co-surgeons (62)9The concept doesn’t apply.
Team surgery (66)9The concept doesn’t apply.
Professional/technical3Technical component only.

Q4112 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • Q4112

    Cymetra injectable, per 1 cc0 wRVU

    Not priced

  • Q4113

    GraftJacket Xpress, per 1 cc0 wRVU

    Not priced

  • Q4116

    Dermal matrix, alloDerm per square centimeter0 wRVU

    $127.26

  • 31574

    Vocal fold injection, flexible scope, unilateral2.37 wRVU

    $901.82

How to choose

Q4113GraftJacket XpressPer 1 cc
Q4113 identifies GraftJacket Xpress, not Cymetra. Select the code for the specific product used.
Q4116Dermal matrixAlloDerm per square centimeter
Q4116 identifies AlloDerm, a separate dermal matrix product. It is not the code for injectable Cymetra.
31574Vocal fold injectionFlexible scope, unilateral
31574 reports flexible laryngoscopy with injection, while Q4112 reports the Cymetra material by volume. They describe different parts of the encounter.

Codes related to Q4112

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to Q4112
CodeHow it relatesNational office range
Often billed with
31574Vocal fold injection, flexible scope, unilateralFlexible laryngoscopy with injection may be reported for vocal-fold augmentation using Cymetra.$781.69–$1,263.26
Used instead
Q4113GraftJacket Xpress, per 1 ccGraftJacket Xpress is a different graft product; report the product actually used.No office rate
Q4116Dermal matrix, alloDerm per square centimeterAlloDerm is another human dermal matrix product, supplied in a different form.$109.31–$183.51

Q4112 billing questions

What does one unit of Q4112 represent?

One unit represents 1 cc of Cymetra. Report units based on the volume used.

Is Q4112 the code for the injection procedure?

No. Q4112 reports the Cymetra material. Report the applicable procedure code separately when the injection service is performed.

How does Medicare price Q4112?

It is carrier priced, so CMS publishes no national payment amount and the Medicare Administrative Contractor sets payment for each claim. The HCPCS pricing method places it under the physician fee schedule.

Does Medicare coverage follow automatically from the code?

No. Coverage is left to the Medicare contractor’s judgment.

How does Q4112 differ from Q4113?

Q4112 identifies Cymetra injectable material per 1 cc. Q4113 identifies GraftJacket Xpress, a different product; use the code matching the material supplied.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

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