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HCPCS code Q4121: Skin substitute, theraSkin per square centimeter2026 Medicare rate & RVUs in New Mexico

Report Q4121 for TheraSkin human skin allograft used to cover a wound, with units based on square centimeters and an application procedure billed with it.

CMS RVU26DEffective Oct 1, 2026One payment locality

In New Mexico, Medicare pays $116.70 for Q4121 in the office.

$116.70Office (non-facility)
Not available in this settingHospital or facility
−8.3%vs the national office rate ($127.26)

Check a contract rate as a % of Medicare · Q4121 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4121 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in New Mexico
  2. What Q4121 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What Q4121 covers

Q4121 reports TheraSkin, a human skin allograft supplied for coverage of a wound bed, commonly in care of chronic diabetic foot and venous leg ulcers. It represents the graft material, not the clinician’s wound preparation or application work. Physicians, podiatrists, and other qualified practitioners may use it in outpatient wound clinics, offices, or hospital outpatient departments when a skin substitute is selected as part of wound care. The product is measured per square centimeter, so the product record and wound documentation should support the quantity reported.

Report Q4121 only with the applicable primary skin-substitute application procedure. CMS treats it as an add-on, with payment within that procedure’s global period. CMS assigns no work RVUs and 3.81 practice-expense RVUs in both office and facility settings. Q4121 is technical-component-only; a separate code covers interpretation. Documentation should identify TheraSkin, the wound location and dimensions, the quantity applied, and the associated application procedure so the product units and procedural service can be reconciled.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How New Mexico compares for Q4121

Across 109 of 109 payment localities, the office rate for Q4121 runs from $109.31 in Arkansas to $183.51 in Santa Clara County, CA. New Mexico pays $116.70. The RVUs are the same everywhere; the geographic indexes change the dollars.

Q4121 in New Mexico vs other payment areas
  1. New Mexico · this page$116.70
  2. Los Angeles, CA · California$150.55+$33.85
  3. Washington, DC area · District of Columbia$149.91+$33.21
  4. Miami, FL · Florida$132.47+$15.77
  5. Chicago, IL · Illinois$127.89+$11.19
  6. Manhattan, NY · New York$147.87+$31.17
  7. Alaska · Alaska$135.53+$18.83

Other areas in New Mexico first, then benchmark localities. Bars start at $0.

Every other payment area

Q4121 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$111.35—
ArkansasArkansas$109.31—
ArizonaArizona$123.31—
Bakersfield, CACalifornia$139.47—
Chico, CACalifornia$139.47—
El Centro, CACalifornia$139.47—
Fresno, CACalifornia$139.47—
Hanford, CACalifornia$139.47—

Q4121 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4121 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

See Q4121 in every payment locality

How the Q4121 rate is calculated

Each of Q4121’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4121

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact New Mexico inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

18,217

Code
Q4121
Physician work
0.00
Practice expense
3.81
Malpractice
0.00

GPCI2026.csv

77

Locality
New Mexico
Physician work
1.000
Practice expense
0.917
Malpractice
1.201
Office calculation for Q4121 in New Mexico
ComponentRVULocality factorAdjusted
Physician work0.00× 1.0000.0000
Practice expense3.81× 0.9173.4938
Malpractice0.00× 1.2010.0000
Total RVUs3.4938
Conversion factor× 33.4009

Office rate, New Mexico$116.70

Office: (0 × 1 + 3.81 × 0.917 + 0 × 1.201) × $33.4009 = $116.70

Open Q4121 in the RVU calculator

Payment rules and modifiers for Q4121

The CMS indicators that decide how Q4121 is paid alongside other services.

CMS payment indicators · Q4121

Skin substitute, theraSkin per square centimeter

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Codes related to Q4121

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to Q4121
CodeHow it relatesOffice range, New Mexico
Primary code
15271Skin substitute graft, first 25 cm², trunk/limbsPrimary skin-substitute application procedure when its site and wound-area criteria fit.$150.91
Used instead
Q4122Wound matrix, dermACELL AWM, per sq cmDermacell AWM is a different wound product measured per square centimeter.$116.70
Q4124Wound matrix, oasis tri-layer productOasis tri-layer wound matrix is a different product used for wound coverage.$116.70
Q4132Wound matrix, grafix Core or GrafixPL CoreGrafix Core is another distinct wound product selected when that material is used.$116.70

How Q4121 has changed in New Mexico

Q4121 · Office / nonfacility

$116.70

Effective 2026-10-01

A rate is unavailable in one of these releases, so a change cannot be calculated.

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    No ratechanged to$116.70

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1, RVU18B, RVU18C, RVU18D, RVU19A, RVU19B, RVU19C, RVU19D, RVU20A, RVU20B, RVU20C, RVU20D, RVU21A, RVU21B, RVU21C, RVU21D, RVU22A, RVU22B, RVU22C, RVU22D, RVU23A, RVU23B, RVU23C, RVU23D, RVU24A, RVU24AR, RVU24B, RVU24C, RVU24D, RVU25A, RVU25B, RVU25C, RVU25D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$116.70Not available in this settingRVU26D
2026-07-01$116.70Not available in this settingRVU26C
2026-04-01$116.70Not available in this settingRVU26B
2026-01-01$116.70Not available in this settingRVU26A
2025-10-01Separate payment rules applySeparate payment rules applyRVU25D
2025-07-01Separate payment rules applySeparate payment rules applyRVU25C
2025-04-01Separate payment rules applySeparate payment rules applyRVU25B
2025-01-01Separate payment rules applySeparate payment rules applyRVU25A
2024-10-01Separate payment rules applySeparate payment rules applyRVU24D
2024-07-01Separate payment rules applySeparate payment rules applyRVU24C
2024-04-01Separate payment rules applySeparate payment rules applyRVU24B
2024-03-09Separate payment rules applySeparate payment rules applyRVU24AR
2024-01-01Separate payment rules applySeparate payment rules applyRVU24A
2023-10-01Separate payment rules applySeparate payment rules applyRVU23D
2023-07-01Separate payment rules applySeparate payment rules applyRVU23C
2023-04-01Separate payment rules applySeparate payment rules applyRVU23B
2023-01-01Separate payment rules applySeparate payment rules applyRVU23A
2022-10-01Separate payment rules applySeparate payment rules applyRVU22D
2022-07-01Separate payment rules applySeparate payment rules applyRVU22C
2022-04-01Separate payment rules applySeparate payment rules applyRVU22B
2022-01-01Separate payment rules applySeparate payment rules applyRVU22A
2021-10-01Separate payment rules applySeparate payment rules applyRVU21D
2021-07-01Separate payment rules applySeparate payment rules applyRVU21C
2021-04-01Separate payment rules applySeparate payment rules applyRVU21B
2021-01-01Separate payment rules applySeparate payment rules applyRVU21A
2020-10-01Separate payment rules applySeparate payment rules applyRVU20D
2020-07-01Separate payment rules applySeparate payment rules applyRVU20C
2020-04-01Separate payment rules applySeparate payment rules applyRVU20B
2020-01-01Separate payment rules applySeparate payment rules applyRVU20A
2019-10-01Separate payment rules applySeparate payment rules applyRVU19D
2019-07-01Separate payment rules applySeparate payment rules applyRVU19C
2019-04-01Separate payment rules applySeparate payment rules applyRVU19B
2019-01-01Separate payment rules applySeparate payment rules applyRVU19A
2018-10-01Separate payment rules applySeparate payment rules applyRVU18D
2018-07-01Separate payment rules applySeparate payment rules applyRVU18C
2018-04-01Separate payment rules applySeparate payment rules applyRVU18B
2018-01-01Separate payment rules applySeparate payment rules applyRVU18AR1
2017-10-01Separate payment rules applySeparate payment rules applyRVU17D
2017-07-01Separate payment rules applySeparate payment rules applyRVU17C
2017-04-01Separate payment rules applySeparate payment rules applyRVU17B
2017-01-01Separate payment rules applySeparate payment rules applyRVU17A
2016-10-01Separate payment rules applySeparate payment rules applyRVU16D
2016-07-01Separate payment rules applySeparate payment rules applyRVU16C
2016-04-01Separate payment rules applySeparate payment rules applyRVU16B
2016-01-01Separate payment rules applySeparate payment rules applyRVU16A
2015-10-01Separate payment rules applySeparate payment rules applyRVU15D
2015-07-01Separate payment rules applySeparate payment rules applyRVU15C
2015-04-01Separate payment rules applySeparate payment rules applyRVU15B
2015-01-01Separate payment rules applySeparate payment rules applyRVU15A
2014-10-01Separate payment rules applySeparate payment rules applyRVU14D
2014-07-01Separate payment rules applySeparate payment rules applyRVU14C
2014-04-01Separate payment rules applySeparate payment rules applyRVU14B
2014-01-01Separate payment rules applySeparate payment rules applyRVU14A
2013-10-01Separate payment rules applySeparate payment rules applyRVU13D
2013-07-01Separate payment rules applySeparate payment rules applyRVU13C
2013-04-01Separate payment rules applySeparate payment rules applyRVU13B
2013-01-01Separate payment rules applySeparate payment rules applyRVU13AR

Price Q4121 for an earlier date of service

Where the New Mexico rate applies

New Mexico is a Medicare payment area, not a city. Our Census mapping connects it to 528 cities and communities in New Mexico. Some span more than one payment area; confirm with the service ZIP.

  • Abeytas
  • Abiquiu
  • Acomita Lake
  • Adelino
  • Agua Fria
  • Alamillo
  • Alamo
  • Alamogordo

Browse all communities in New Mexico

Q4121 billing questions

What distinguishes Q4121 from another skin substitute product code?

Q4121 identifies TheraSkin specifically. Report the product code matching the graft material used, rather than choosing among products based only on wound type.

Does Q4121 include the wound application procedure?

No. Q4121 represents the TheraSkin product and is reported with the applicable primary skin-substitute application procedure.

How should units be determined?

Q4121 is measured per square centimeter. The product record and wound documentation should support the quantity reported.

How does the add-on status affect payment?

CMS requires Q4121 to be billed with a primary procedure and places its payment within that procedure’s global period.

Does Q4121 include interpretation?

CMS classifies Q4121 as technical-component-only; a separate code covers interpretation.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4121PPRRVU2026_Oct_nonQPP.csv, line 18,217 (RVU26D)
Geographic factors for New MexicoGPCI2026.csv, line 77 (RVU26D)

Open CMS sourceHow we calculate rates

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