HCPCS code Q4211: Wound product, amnion Bio or AxoBio2026 Medicare rate & RVUs in Guam
Reports Amnion Bio or AxoBio biologic wound product by square centimeter when used with a qualifying wound graft application procedure.
Medicare pays $144.69 for Q4211 in the office in Guam (Hawaii, Guam, HI). Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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What Q4211 covers
Q4211 identifies the Amnion Bio or AxoBio product supplied for wound coverage, measured by square centimeter. It represents the biologic material, not the clinician’s work to prepare or apply it. Physicians and other qualified practitioners may use these products during wound care in office or hospital outpatient settings; the application procedure is reported separately according to the wound site and treated area.
Report the product code with a primary procedure, using the documented product name and square centimeters represented by the billed units. The record should support the product used, the wound site, and the amount applied. CMS classifies Q4211 as an add-on code, so it is not billed alone and is paid within the primary procedure’s global period. It is a technical-component-only code; a separate code covers interpretation.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Q4211 in Hawaii, Guam, HI
| Payment locality | Office | Facility |
|---|---|---|
| Hawaii, Guam, HI | $144.69 | Unavailable |
How the Q4211 rate is calculated
Each of Q4211’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4211
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4211
The CMS indicators that decide how Q4211 is paid alongside other services.
CMS payment indicators · Q4211
Wound product, amnion Bio or AxoBio
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4211 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- 15271Skin substitute graftFirst 25 cm², trunk/limbs
- Q4211 reports the Amnion Bio or AxoBio product by square centimeter; 15271 reports the application service for its specified sites and area.
- 15275Skin substituteFace and other specified sites
- 15275 reports the application service for a different anatomic-site grouping than 15271. Q4211 identifies the product used and does not determine the application code.
- Q4221Wound productAmnioWrap2, per square centimeter
- Q4221 identifies Amniowrap2, while Q4211 identifies Amnion Bio or AxoBio. Select according to the product used.
Q4211 billing questions
What distinguishes Q4211 from another amnion product code?
Q4211 identifies Amnion Bio or AxoBio. Use the code that matches the product actually supplied, rather than choosing by the general tissue type alone.
Can Q4211 be billed by itself?
No. CMS identifies it as an add-on code that must be billed with a primary procedure.
Which application procedure is reported with Q4211?
Report the procedure code that matches the wound location and treated area. Codes 15271–15278 cover different site and area groupings for skin substitute graft application.
How are units supported?
The code is measured per square centimeter. Document the product used and the square centimeters represented by the billed units.
Does Q4211 include interpretation?
No. CMS classifies Q4211 as technical-component-only; a separate code covers interpretation.
How does the global-period rule affect payment?
Q4211 is paid within the primary procedure’s global period and must be reported with that primary procedure.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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