HCPCS code Q4249: Amniply, per square centimeter2026 Medicare rate & RVUs in Minnesota
Reports the Amniply amniotic membrane product by square centimeter when furnished for application to a wound during a separately coded wound procedure.
In Minnesota, Medicare pays $130.95 for Q4249 in the office.
Check a contract rate as a % of Medicare · Q4249 nationwide
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 11 sections
What Q4249 covers
Q4249 represents the Amniply amniotic membrane product supplied for wound treatment, measured by the square centimeter. Wound-care clinicians, surgeons, and podiatrists may use it when applying the product to a prepared wound bed in an office or other treatment setting. The code identifies the product, not the wound preparation or application service itself.
Report the number of square centimeters represented by the Amniply product furnished, and retain documentation identifying the product and supporting the quantity reported. CMS classifies Q4249 as an add-on code: bill it only with a primary procedure, such as an applicable skin-substitute application procedure, and payment is within that procedure’s global period. It is a technical-component-only code; a separate code covers interpretation.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
How Minnesota compares for Q4249
Across 109 of 109 payment localities, the office rate for Q4249 runs from $109.31 in Arkansas to $183.51 in Santa Clara County, CA. Minnesota pays $130.95. The RVUs are the same everywhere; the geographic indexes change the dollars.
- Minnesota · this page$130.95
- Los Angeles, CA · California$150.55+$19.60
- Washington, DC area · District of Columbia$149.91+$18.96
- Miami, FL · Florida$132.47+$1.52
- Chicago, IL · Illinois$127.89−$3.06
- Manhattan, NY · New York$147.87+$16.92
- Alaska · Alaska$135.53+$4.58
Other areas in Minnesota first, then benchmark localities. Bars start at $0.
Every other payment area
| Payment locality | Office | Facility |
|---|---|---|
| AlabamaAlabama | $111.35 | — |
| ArkansasArkansas | $109.31 | — |
| ArizonaArizona | $123.31 | — |
| Bakersfield, CACalifornia | $139.47 | — |
| Chico, CACalifornia | $139.47 | — |
| El Centro, CACalifornia | $139.47 | — |
| Fresno, CACalifornia | $139.47 | — |
| Hanford, CACalifornia | $139.47 | — |
| Madera, CACalifornia | $139.47 | — |
| Merced, CACalifornia | $139.47 | — |
| Modesto, CACalifornia | $139.47 | — |
| Napa, CACalifornia | $167.73 | — |
| Oxnard, CACalifornia | $150.42 | — |
| Redding, CACalifornia | $139.47 | — |
| Rest of CaliforniaCalifornia | $139.47 | — |
| Riverside, CACalifornia | $139.47 | — |
| Sacramento, CACalifornia | $148.00 | — |
| Salinas, CACalifornia | $147.49 | — |
| San Diego, CACalifornia | $152.20 | — |
| Marin County, CACalifornia | $179.43 | — |
| San Francisco, CACalifornia | $179.43 | — |
| San Benito County, CACalifornia | $183.51 | — |
| Santa Clara County, CACalifornia | $183.51 | — |
| San Luis Obispo, CACalifornia | $144.95 | — |
| Santa Cruz, CACalifornia | $154.62 | — |
| Santa Maria, CACalifornia | $148.38 | — |
| Santa Rosa, CACalifornia | $156.27 | — |
| Stockton, CACalifornia | $139.47 | — |
| Vallejo, CACalifornia | $167.73 | — |
| Visalia, CACalifornia | $139.47 | — |
| Yuba City, CACalifornia | $139.47 | — |
| ColoradoColorado | $135.40 | — |
| ConnecticutConnecticut | $137.06 | — |
| DelawareDelaware | $125.73 | — |
| Fort Lauderdale, FLFlorida | $128.91 | — |
| Rest of FloridaFlorida | $121.66 | — |
| Atlanta, GAGeorgia | $129.29 | — |
| Rest of GeorgiaGeorgia | $113.51 | — |
| Hawaii, Guam, HIHawaii | $144.69 | — |
| IowaIowa | $116.44 | — |
| IdahoIdaho | $117.08 | — |
| East St. Louis, ILIllinois | $117.08 | — |
| Rest of IllinoisIllinois | $116.19 | — |
| Suburban Chicago, ILIllinois | $130.69 | — |
| IndianaIndiana | $117.97 | — |
| KansasKansas | $115.04 | — |
| KentuckyKentucky | $113.13 | — |
| New Orleans, LALouisiana | $119.75 | — |
| Rest of LouisianaLouisiana | $112.62 | — |
| Metropolitan Boston, MAMassachusetts | $151.95 | — |
| Rest of MassachusettsMassachusetts | $134.00 | — |
| Baltimore area, MDMaryland | $136.55 | — |
| Rest of MarylandMaryland | $128.78 | — |
| Rest of MaineMaine | $117.08 | — |
| Southern Maine, MEMaine | $126.11 | — |
| Detroit, MIMichigan | $122.80 | — |
| Rest of MichiganMichigan | $116.19 | — |
| Metropolitan Kansas City, MOMissouri | $119.49 | — |
| Metropolitan St. Louis, MOMissouri | $121.15 | — |
| Rest of MissouriMissouri | $109.70 | — |
| MississippiMississippi | $109.57 | — |
| MontanaMontana | $127.26 | — |
| North CarolinaNorth Carolina | $118.73 | — |
| North DakotaNorth Dakota | $127.26 | — |
| NebraskaNebraska | $117.46 | — |
| New HampshireNew Hampshire | $132.47 | — |
| Northern New JerseyNew Jersey | $147.62 | — |
| Rest of New JerseyNew Jersey | $138.97 | — |
| New MexicoNew Mexico | $116.70 | — |
| NevadaNevada | $127.38 | — |
| NYC suburbs and Long Island, NYNew York | $151.31 | — |
| Poughkeepsie and northern NYC suburbs, NYNew York | $139.35 | — |
| Queens, NYNew York | $150.42 | — |
| Rest of New YorkNew York | $120.89 | — |
| OhioOhio | $116.19 | — |
| OklahomaOklahoma | $113.64 | — |
| Portland, OROregon | $141.38 | — |
| Rest of OregonOregon | $126.75 | — |
| Metropolitan Philadelphia, PAPennsylvania | $132.47 | — |
| Rest of PennsylvaniaPennsylvania | $116.82 | — |
| Puerto RicoPuerto Rico | $128.66 | — |
| Rhode IslandRhode Island | $131.46 | — |
| South CarolinaSouth Carolina | $117.59 | — |
| South DakotaSouth Dakota | $127.26 | — |
| TennesseeTennessee | $115.68 | — |
| Austin, TXTexas | $134.64 | — |
| Beaumont, TXTexas | $115.80 | — |
| Brazoria, TXTexas | $126.11 | — |
| Dallas, TXTexas | $126.75 | — |
| Fort Worth, TXTexas | $125.48 | — |
| Galveston, TXTexas | $126.37 | — |
| Houston, TXTexas | $126.37 | — |
| Rest of TexasTexas | $120.77 | — |
| UtahUtah | $119.62 | — |
| VirginiaVirginia | $125.09 | — |
| Virgin Islands, VIUnited States Virgin Islands | $128.66 | — |
| VermontVermont | $125.98 | — |
| Rest of WashingtonWashington | $134.00 | — |
| King County, WAWashington | $156.14 | — |
| WisconsinWisconsin | $121.91 | — |
| West VirginiaWest Virginia | $110.59 | — |
| WyomingWyoming | $127.26 | — |
Q4249 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$109.31
$161.49
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $135.53 | 1 |
| AL | $111.35 | 1 |
| AR | $109.31 | 1 |
| AZ | $123.31 | 1 |
| CA | $139.47–$183.51 | 29 |
| CO | $135.40 | 1 |
| CT | $137.06 | 1 |
| DC | $149.91 | 1 |
| DE | $125.73 | 1 |
| FL | $121.66–$132.47 | 3 |
| GA | $113.51–$129.29 | 2 |
| GU | $144.69 | 1 |
| HI | $144.69 | 1 |
| IA | $116.44 | 1 |
| ID | $117.08 | 1 |
| IL | $116.19–$130.69 | 4 |
| IN | $117.97 | 1 |
| KS | $115.04 | 1 |
| KY | $113.13 | 1 |
| LA | $112.62–$119.75 | 2 |
| MA | $134.00–$151.95 | 2 |
| MD | $128.78–$149.91 | 3 |
| ME | $117.08–$126.11 | 2 |
| MI | $116.19–$122.80 | 2 |
| MN | $130.95 | 1 |
| MO | $109.70–$121.15 | 3 |
| MS | $109.57 | 1 |
| MT | $127.26 | 1 |
| NC | $118.73 | 1 |
| ND | $127.26 | 1 |
| NE | $117.46 | 1 |
| NH | $132.47 | 1 |
| NJ | $138.97–$147.62 | 2 |
| NM | $116.70 | 1 |
| NV | $127.38 | 1 |
| NY | $120.89–$151.31 | 5 |
| OH | $116.19 | 1 |
| OK | $113.64 | 1 |
| OR | $126.75–$141.38 | 2 |
| PA | $116.82–$132.47 | 2 |
| PR | $128.66 | 1 |
| RI | $131.46 | 1 |
| SC | $117.59 | 1 |
| SD | $127.26 | 1 |
| TN | $115.68 | 1 |
| TX | $115.80–$134.64 | 8 |
| UT | $119.62 | 1 |
| VA | $125.09–$149.91 | 2 |
| VI | $128.66 | 1 |
| VT | $125.98 | 1 |
| WA | $134.00–$156.14 | 2 |
| WI | $121.91 | 1 |
| WV | $110.59 | 1 |
| WY | $127.26 | 1 |
How the Q4249 rate is calculated
Each of Q4249’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4249
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
The exact Minnesota inputs and CMS source lines
PPRRVU2026_Oct_nonQPP.csv
18,337
- Code
- Q4249
- Physician work
- 0.00
- Practice expense
- 3.81
- Malpractice
- 0.00
GPCI2026.csv
66
- Locality
- Minnesota
- Physician work
- 1.000
- Practice expense
- 1.029
- Malpractice
- 0.296
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.00 | × 1.000 | 0.0000 |
| Practice expense | 3.81 | × 1.029 | 3.9205 |
| Malpractice | 0.00 | × 0.296 | 0.0000 |
| Total RVUs | 3.9205 | ||
| Conversion factor | × 33.4009 | ||
Office rate, Minnesota$130.95
Office: (0 × 1 + 3.81 × 1.029 + 0 × 0.296) × $33.4009 = $130.95
Payment rules and modifiers for Q4249
The CMS indicators that decide how Q4249 is paid alongside other services.
CMS payment indicators · Q4249
Amniply, per square centimeter
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
How Q4249 has changed in Minnesota
Q4249 · Office / nonfacility
$130.95
Effective 2026-10-01
A rate is unavailable in one of these releases, so a change cannot be calculated.
It is unchanged from the immediately preceding available release, effective 2026-07-01.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2026
RVU26A
No ratechanged to$130.95
Held through RVU26B, RVU26C, RVU26D.
October 1, 2020
RVU20D
No ratechanged toNo rate
Held through RVU21A, RVU21B, RVU21C, RVU21D, RVU22A, RVU22B, RVU22C, RVU22D, RVU23A, RVU23B, RVU23C, RVU23D, RVU24A, RVU24AR, RVU24B, RVU24C, RVU24D, RVU25A, RVU25B, RVU25C, RVU25D.
January 1, 2013
RVU13AR
Earliest loaded release: No rate
Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1, RVU18B, RVU18C, RVU18D, RVU19A, RVU19B, RVU19C, RVU19D, RVU20A, RVU20B, RVU20C.
| Effective from | Office | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | $130.95 | Not available in this setting | RVU26D |
| 2026-07-01 | $130.95 | Not available in this setting | RVU26C |
| 2026-04-01 | $130.95 | Not available in this setting | RVU26B |
| 2026-01-01 | $130.95 | Not available in this setting | RVU26A |
| 2025-10-01 | Separate payment rules apply | Separate payment rules apply | RVU25D |
| 2025-07-01 | Separate payment rules apply | Separate payment rules apply | RVU25C |
| 2025-04-01 | Separate payment rules apply | Separate payment rules apply | RVU25B |
| 2025-01-01 | Separate payment rules apply | Separate payment rules apply | RVU25A |
| 2024-10-01 | Separate payment rules apply | Separate payment rules apply | RVU24D |
| 2024-07-01 | Separate payment rules apply | Separate payment rules apply | RVU24C |
| 2024-04-01 | Separate payment rules apply | Separate payment rules apply | RVU24B |
| 2024-03-09 | Separate payment rules apply | Separate payment rules apply | RVU24AR |
| 2024-01-01 | Separate payment rules apply | Separate payment rules apply | RVU24A |
| 2023-10-01 | Separate payment rules apply | Separate payment rules apply | RVU23D |
| 2023-07-01 | Separate payment rules apply | Separate payment rules apply | RVU23C |
| 2023-04-01 | Separate payment rules apply | Separate payment rules apply | RVU23B |
| 2023-01-01 | Separate payment rules apply | Separate payment rules apply | RVU23A |
| 2022-10-01 | Separate payment rules apply | Separate payment rules apply | RVU22D |
| 2022-07-01 | Separate payment rules apply | Separate payment rules apply | RVU22C |
| 2022-04-01 | Separate payment rules apply | Separate payment rules apply | RVU22B |
| 2022-01-01 | Separate payment rules apply | Separate payment rules apply | RVU22A |
| 2021-10-01 | Separate payment rules apply | Separate payment rules apply | RVU21D |
| 2021-07-01 | Separate payment rules apply | Separate payment rules apply | RVU21C |
| 2021-04-01 | Separate payment rules apply | Separate payment rules apply | RVU21B |
| 2021-01-01 | Separate payment rules apply | Separate payment rules apply | RVU21A |
| 2020-10-01 | Separate payment rules apply | Separate payment rules apply | RVU20D |
| 2020-07-01 | Not in this release | Not in this release | RVU20C |
| 2020-04-01 | Not in this release | Not in this release | RVU20B |
| 2020-01-01 | Not in this release | Not in this release | RVU20A |
| 2019-10-01 | Not in this release | Not in this release | RVU19D |
| 2019-07-01 | Not in this release | Not in this release | RVU19C |
| 2019-04-01 | Not in this release | Not in this release | RVU19B |
| 2019-01-01 | Not in this release | Not in this release | RVU19A |
| 2018-10-01 | Not in this release | Not in this release | RVU18D |
| 2018-07-01 | Not in this release | Not in this release | RVU18C |
| 2018-04-01 | Not in this release | Not in this release | RVU18B |
| 2018-01-01 | Not in this release | Not in this release | RVU18AR1 |
| 2017-10-01 | Not in this release | Not in this release | RVU17D |
| 2017-07-01 | Not in this release | Not in this release | RVU17C |
| 2017-04-01 | Not in this release | Not in this release | RVU17B |
| 2017-01-01 | Not in this release | Not in this release | RVU17A |
| 2016-10-01 | Not in this release | Not in this release | RVU16D |
| 2016-07-01 | Not in this release | Not in this release | RVU16C |
| 2016-04-01 | Not in this release | Not in this release | RVU16B |
| 2016-01-01 | Not in this release | Not in this release | RVU16A |
| 2015-10-01 | Not in this release | Not in this release | RVU15D |
| 2015-07-01 | Not in this release | Not in this release | RVU15C |
| 2015-04-01 | Not in this release | Not in this release | RVU15B |
| 2015-01-01 | Not in this release | Not in this release | RVU15A |
| 2014-10-01 | Not in this release | Not in this release | RVU14D |
| 2014-07-01 | Not in this release | Not in this release | RVU14C |
| 2014-04-01 | Not in this release | Not in this release | RVU14B |
| 2014-01-01 | Not in this release | Not in this release | RVU14A |
| 2013-10-01 | Not in this release | Not in this release | RVU13D |
| 2013-07-01 | Not in this release | Not in this release | RVU13C |
| 2013-04-01 | Not in this release | Not in this release | RVU13B |
| 2013-01-01 | Not in this release | Not in this release | RVU13AR |
Where the Minnesota rate applies
Minnesota is a Medicare payment area, not a city. Our Census mapping connects it to 916 cities and communities in Minnesota. Some span more than one payment area; confirm with the service ZIP.
- Ada
- Adams
- Adrian
- Afton
- Aitkin
- Akeley
- Albany
- Albert Lea
Q4249 billing questions
How is Q4249 different from the skin-substitute application code?
Q4249 reports the Amniply product by square centimeter. The primary application code reports the wound application service.
Can Q4249 be billed by itself?
No. CMS identifies Q4249 as an add-on code that must be billed with a primary procedure.
What quantity should be reported?
Report the square centimeters of Amniply product furnished. Documentation should identify the product and support the quantity.
Is a separate interpretation code needed?
CMS classifies Q4249 as technical-component-only and specifies that a separate code covers interpretation.
How does the global-period rule affect payment?
Payment for Q4249 is within the primary procedure’s global period, so it is not paid separately from that procedure’s global payment.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
Fee sheets · Coming soon
Put Q4249 and the rest of your codes on one sheet
Your codes at your locality, with payer contracts beside Medicare.
Join the waitlist