HCPCS code Q4304: Wound product, grafix Plus, per square centimeter2026 Medicare rate & RVUs in Missouri
Reports the per-square-centimeter amount of Grafix Plus supplied for wound treatment when billed with the applicable primary application procedure.
Medicare pays $109.70–$121.15 for Q4304 in the office in Missouri, from Rest of Missouri to Metropolitan St. Louis, MO. Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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On this page 9 sections
What Q4304 covers
Q4304 identifies Grafix Plus supplied for application to a wound. It is a product code, not the wound preparation or application service itself. Wound-care clinicians may use the product during treatment of open wounds, including chronic wounds managed in outpatient wound clinics or other settings. The product record and treatment note should make clear that Grafix Plus, rather than another wound product, was used.
Report the product quantity in square centimeters and pair Q4304 with the primary procedure that applies the product; it is an add-on and is paid within that procedure’s global period. Documentation should support the product used, the wound treated, and the amount supplied or applied. CMS classifies Q4304 as technical-component-only: the code represents the technical portion, while a separate code covers interpretation. The wound application service and the product quantity are distinct reporting elements.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where Q4304 pays more and less in Missouri
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
3 payment localities
$109.70 to $121.15
| Payment locality | Office | Facility |
|---|---|---|
| Metropolitan Kansas City, MO | $119.49 | Unavailable |
| Metropolitan St. Louis, MO | $121.15 | Unavailable |
| Rest of Missouri | $109.70 | Unavailable |
How the Q4304 rate is calculated
Each of Q4304’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4304
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4304
The CMS indicators that decide how Q4304 is paid alongside other services.
CMS payment indicators · Q4304
Wound product, grafix Plus, per square centimeter
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4304 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- 15271Skin substitute graftFirst 25 cm², trunk/limbs
- 15271 reports the primary application service for an eligible site and wound area; Q4304 reports the Grafix Plus product quantity and is an add-on.
- 15275Skin substituteFace and other specified sites
- 15275 is an application procedure for specified sites such as the face, hands, feet, or genitalia. Q4304 identifies the product used, not the application service.
- Q4305Wound allograftAmerican Amnion AC Tri-Layer
- Q4305 identifies a different wound product billed per square centimeter. Use the code matching the product actually furnished rather than substituting it for Grafix Plus.
Q4304 billing questions
Can Q4304 be billed by itself?
No. CMS identifies it as an add-on code, so report it with the applicable primary wound application procedure.
How is the quantity reported?
The descriptor is per square centimeter. Documentation should support the amount of Grafix Plus supplied or applied to the wound.
Does Q4304 include the wound application?
No. Q4304 identifies the product; the primary procedure represents the application service. For an appropriate site and size, 15271 may be the primary application code.
Is an interpretation included in Q4304?
No. CMS classifies Q4304 as technical-component-only and specifies that a separate code covers interpretation.
What documentation helps support Q4304?
Record the product as Grafix Plus, identify the treated wound, and document the quantity used in square centimeters along with the associated application procedure.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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