HCPCS code Q4324: Amniotic graft, amnioTx, per square centimeter2026 Medicare rate & RVUs in Missouri

Reports AmnioTx amniotic tissue used for wound coverage, billed per square centimeter with the primary procedure that applies the graft.

CMS RVU26DEffective Oct 1, 20263 payment localities

Medicare pays $109.70–$121.15 for Q4324 in the office in Missouri, from Rest of Missouri to Metropolitan St. Louis, MO. Which amount applies depends on the service address.

$109.70–$121.15Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Missouri
  2. What Q4324 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4324 covers

Q4324 identifies AmnioTx, an amniotic tissue product used as a covering for skin wounds, including chronic or difficult-to-heal ulcers. It represents the product, not the clinician’s work to prepare the wound or apply the graft. Physicians and other qualified practitioners involved in wound care may use it in an office or facility setting as part of a graft application service.

Report the documented square centimeters of product used and pair Q4324 with the primary application procedure selected for the treated site and wound area; it is not a standalone service. Keep the product record and procedure note consistent about the product and amount applied. CMS treats Q4324 as an add-on paid within the primary procedure’s global period. It is also classified as technical-component-only, with interpretation covered by a separate code.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4324 pays more and less in Missouri

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

3 payment localities

$109.70 to $121.15

$109.70$115.43$121.15
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.
Q4324 office and facility rates by payment locality
Payment localityOfficeFacility
Metropolitan Kansas City, MO$119.49Unavailable
Metropolitan St. Louis, MO$121.15Unavailable
Rest of Missouri$109.70Unavailable

How the Q4324 rate is calculated

Each of Q4324’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4324

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4324

The CMS indicators that decide how Q4324 is paid alongside other services.

CMS payment indicators · Q4324

Amniotic graft, amnioTx, per square centimeter

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4324 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • Q4324

    Amniotic graft, amnioTx, per square centimeter0 wRVU

    $127.26

  • Q4323

    AlloPly, per square centimeter0 wRVU

    $127.26+$0.00

  • Q4325

    Wound product, acapatch, per square centimeter0 wRVU

    $127.26+$0.00

  • 15271

    Skin substitute graft, first 25 cm², trunk/limbs1.46 wRVU

    $157.99+$30.73

How to choose

Q4323AlloPlyPer square centimeter
Q4323 identifies Alloply, while Q4324 identifies AmnioTx. Select the code that matches the product documented as used.
Q4325Wound productAcapatch, per square centimeter
Q4325 identifies Acapatch, not AmnioTx. The product name in the record determines which supply code to report.
15271Skin substitute graftFirst 25 cm², trunk/limbs
15271 reports the primary graft-application procedure; Q4324 identifies the AmnioTx product and is reported as an add-on with a primary procedure.

Q4324 billing questions

Can Q4324 be reported by itself?

No. It is an add-on for the primary procedure that applies the graft, and CMS pays it within that procedure’s global period.

How should the quantity be reported?

Report the quantity in square centimeters. Documentation should identify AmnioTx and support the amount used for the graft application.

Is Q4324 the application procedure?

No. Q4324 identifies the AmnioTx product; a separate primary procedure reports application of the graft to the wound.

Does Q4324 include professional interpretation?

No. CMS classifies Q4324 as technical-component-only; a separate code covers interpretation.

How is Q4324 distinguished from Q4323 or Q4325?

These codes identify different wound products. Use Q4324 for AmnioTx, rather than selecting it based only on wound location or size.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4324PPRRVU2026_Oct_nonQPP.csv, line 18,411 (RVU26D)

Open CMS sourceHow we calculate rates

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