HCPCS code Q5110: Nivestym, per 1 mcg2026 Medicare rate & RVUs in North Carolina
Q5110 reports Nivestym, a filgrastim biosimilar, by microgram for covered treatment or prevention of neutropenia and related indications.
CMS doesn’t publish a rate for Q5110 in North Carolina.
Check a contract rate as a % of Medicare · Q5110 nationwide
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 11 sections
What Q5110 covers
Q5110 identifies Nivestym (filgrastim-aafi), a biosimilar granulocyte colony-stimulating factor. Oncology practices commonly use filgrastim products to reduce infection risk from neutropenia associated with cancer treatment. Filgrastim is also used in settings such as bone marrow transplantation and stem-cell mobilization. It is administered by subcutaneous injection or intravenous infusion, depending on clinical use. Q5110 identifies the drug, not the administration service.
CMS assigns Q5110 to the Part B drug pricing method; when Medicare covers it, payment generally uses CMS’s quarterly Average Sales Price drug pricing files. Its physician fee schedule status is E, meaning CMS excludes it from the physician fee schedule and, when covered, pays under another method. CMS also assigns special Medicare coverage instructions to this code. One unit represents 1 microgram of filgrastim-aafi, so reported units correspond to the total microgram dose furnished.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
How North Carolina compares for Q5110
- North Carolina · this pageUnavailable
- Los Angeles, CA · CaliforniaUnavailable
- Washington, DC area · District of ColumbiaUnavailable
- Miami, FL · FloridaUnavailable
- Chicago, IL · IllinoisUnavailable
- Manhattan, NY · New YorkUnavailable
- Alaska · AlaskaUnavailable
Other areas in North Carolina first, then benchmark localities. Bars start at $0.
Every other payment area
Q5110 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | No published base rate | 1 |
| AL | No published base rate | 1 |
| AR | No published base rate | 1 |
| AZ | No published base rate | 1 |
| CA | No published base rate | 29 |
| CO | No published base rate | 1 |
| CT | No published base rate | 1 |
| DC | No published base rate | 1 |
| DE | No published base rate | 1 |
| FL | No published base rate | 3 |
| GA | No published base rate | 2 |
| GU | No published base rate | 1 |
| HI | No published base rate | 1 |
| IA | No published base rate | 1 |
| ID | No published base rate | 1 |
| IL | No published base rate | 4 |
| IN | No published base rate | 1 |
| KS | No published base rate | 1 |
| KY | No published base rate | 1 |
| LA | No published base rate | 2 |
| MA | No published base rate | 2 |
| MD | No published base rate | 3 |
| ME | No published base rate | 2 |
| MI | No published base rate | 2 |
| MN | No published base rate | 1 |
| MO | No published base rate | 3 |
| MS | No published base rate | 1 |
| MT | No published base rate | 1 |
| NC | No published base rate | 1 |
| ND | No published base rate | 1 |
| NE | No published base rate | 1 |
| NH | No published base rate | 1 |
| NJ | No published base rate | 2 |
| NM | No published base rate | 1 |
| NV | No published base rate | 1 |
| NY | No published base rate | 5 |
| OH | No published base rate | 1 |
| OK | No published base rate | 1 |
| OR | No published base rate | 2 |
| PA | No published base rate | 2 |
| PR | No published base rate | 1 |
| RI | No published base rate | 1 |
| SC | No published base rate | 1 |
| SD | No published base rate | 1 |
| TN | No published base rate | 1 |
| TX | No published base rate | 8 |
| UT | No published base rate | 1 |
| VA | No published base rate | 2 |
| VI | No published base rate | 1 |
| VT | No published base rate | 1 |
| WA | No published base rate | 2 |
| WI | No published base rate | 1 |
| WV | No published base rate | 1 |
| WY | No published base rate | 1 |
How the Q5110 rate is calculated
Each of Q5110’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q5110
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense0.00
0.00 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
0.0000
Conversion factor
$33.4009
Medicare rate
$0.00
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q5110
Q5110 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.
Place of service · Q5110
Which rate does Medicare pay?
The POS code on the claim line (CMS-1500 box 24B).
POS 11 · non-facility rate · national
—
Q5110 isn’t priced in this setting.
How Q5110 has changed in North Carolina
Q5110 · Office / nonfacility
Rate unavailable
Effective 2026-10-01
A rate is unavailable in one of these releases, so a change cannot be calculated.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2019
RVU19A
No ratechanged toNo rate
Held through RVU19B, RVU19C, RVU19D, RVU20A, RVU20B, RVU20C, RVU20D, RVU21A, RVU21B, RVU21C, RVU21D, RVU22A, RVU22B, RVU22C, RVU22D, RVU23A, RVU23B, RVU23C, RVU23D, RVU24A, RVU24AR, RVU24B, RVU24C, RVU24D, RVU25A, RVU25B, RVU25C, RVU25D, RVU26A, RVU26B, RVU26C, RVU26D.
January 1, 2013
RVU13AR
Earliest loaded release: No rate
Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1, RVU18B, RVU18C, RVU18D.
| Effective from | Office | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | Separate payment rules apply | Separate payment rules apply | RVU26D |
| 2026-07-01 | Separate payment rules apply | Separate payment rules apply | RVU26C |
| 2026-04-01 | Separate payment rules apply | Separate payment rules apply | RVU26B |
| 2026-01-01 | Separate payment rules apply | Separate payment rules apply | RVU26A |
| 2025-10-01 | Separate payment rules apply | Separate payment rules apply | RVU25D |
| 2025-07-01 | Separate payment rules apply | Separate payment rules apply | RVU25C |
| 2025-04-01 | Separate payment rules apply | Separate payment rules apply | RVU25B |
| 2025-01-01 | Separate payment rules apply | Separate payment rules apply | RVU25A |
| 2024-10-01 | Separate payment rules apply | Separate payment rules apply | RVU24D |
| 2024-07-01 | Separate payment rules apply | Separate payment rules apply | RVU24C |
| 2024-04-01 | Separate payment rules apply | Separate payment rules apply | RVU24B |
| 2024-03-09 | Separate payment rules apply | Separate payment rules apply | RVU24AR |
| 2024-01-01 | Separate payment rules apply | Separate payment rules apply | RVU24A |
| 2023-10-01 | Separate payment rules apply | Separate payment rules apply | RVU23D |
| 2023-07-01 | Separate payment rules apply | Separate payment rules apply | RVU23C |
| 2023-04-01 | Separate payment rules apply | Separate payment rules apply | RVU23B |
| 2023-01-01 | Separate payment rules apply | Separate payment rules apply | RVU23A |
| 2022-10-01 | Separate payment rules apply | Separate payment rules apply | RVU22D |
| 2022-07-01 | Separate payment rules apply | Separate payment rules apply | RVU22C |
| 2022-04-01 | Separate payment rules apply | Separate payment rules apply | RVU22B |
| 2022-01-01 | Separate payment rules apply | Separate payment rules apply | RVU22A |
| 2021-10-01 | Separate payment rules apply | Separate payment rules apply | RVU21D |
| 2021-07-01 | Separate payment rules apply | Separate payment rules apply | RVU21C |
| 2021-04-01 | Separate payment rules apply | Separate payment rules apply | RVU21B |
| 2021-01-01 | Separate payment rules apply | Separate payment rules apply | RVU21A |
| 2020-10-01 | Separate payment rules apply | Separate payment rules apply | RVU20D |
| 2020-07-01 | Separate payment rules apply | Separate payment rules apply | RVU20C |
| 2020-04-01 | Separate payment rules apply | Separate payment rules apply | RVU20B |
| 2020-01-01 | Separate payment rules apply | Separate payment rules apply | RVU20A |
| 2019-10-01 | Separate payment rules apply | Separate payment rules apply | RVU19D |
| 2019-07-01 | Separate payment rules apply | Separate payment rules apply | RVU19C |
| 2019-04-01 | Separate payment rules apply | Separate payment rules apply | RVU19B |
| 2019-01-01 | Separate payment rules apply | Separate payment rules apply | RVU19A |
| 2018-10-01 | Not in this release | Not in this release | RVU18D |
| 2018-07-01 | Not in this release | Not in this release | RVU18C |
| 2018-04-01 | Not in this release | Not in this release | RVU18B |
| 2018-01-01 | Not in this release | Not in this release | RVU18AR1 |
| 2017-10-01 | Not in this release | Not in this release | RVU17D |
| 2017-07-01 | Not in this release | Not in this release | RVU17C |
| 2017-04-01 | Not in this release | Not in this release | RVU17B |
| 2017-01-01 | Not in this release | Not in this release | RVU17A |
| 2016-10-01 | Not in this release | Not in this release | RVU16D |
| 2016-07-01 | Not in this release | Not in this release | RVU16C |
| 2016-04-01 | Not in this release | Not in this release | RVU16B |
| 2016-01-01 | Not in this release | Not in this release | RVU16A |
| 2015-10-01 | Not in this release | Not in this release | RVU15D |
| 2015-07-01 | Not in this release | Not in this release | RVU15C |
| 2015-04-01 | Not in this release | Not in this release | RVU15B |
| 2015-01-01 | Not in this release | Not in this release | RVU15A |
| 2014-10-01 | Not in this release | Not in this release | RVU14D |
| 2014-07-01 | Not in this release | Not in this release | RVU14C |
| 2014-04-01 | Not in this release | Not in this release | RVU14B |
| 2014-01-01 | Not in this release | Not in this release | RVU14A |
| 2013-10-01 | Not in this release | Not in this release | RVU13D |
| 2013-07-01 | Not in this release | Not in this release | RVU13C |
| 2013-04-01 | Not in this release | Not in this release | RVU13B |
| 2013-01-01 | Not in this release | Not in this release | RVU13AR |
Where the North Carolina rate applies
North Carolina is a Medicare payment area, not a city. Our Census mapping connects it to 785 cities and communities in North Carolina. Some span more than one payment area; confirm with the service ZIP.
- Aberdeen
- Advance
- Ahoskie
- Alamance
- Albemarle
- Alexis
- Alliance
- Altamahaw
Q5110 billing questions
What does one Q5110 unit represent?
One unit represents 1 microgram of filgrastim-aafi. Report units based on the total Nivestym dose furnished.
How is Q5110 different from Q5101?
Q5110 is for filgrastim-aafi (Nivestym), while Q5101 is for filgrastim-sndz (Zarxio). Select the code matching the product administered.
How is Q5110 different from Q5125?
Q5125 identifies filgrastim-ayow (Releuko), while Q5110 identifies filgrastim-aafi (Nivestym). Both are filgrastim biosimilars, but each has a product-specific code.
Does Q5110 include the injection or infusion service?
Q5110 reports the drug amount, not the act of administering it.
How does Medicare price Q5110?
CMS excludes Q5110 from the physician fee schedule (status E). When Medicare covers the drug, it generally uses the quarterly ASP drug pricing files under the Part B drug pricing method.
Does Q5110 have Medicare coverage instructions?
Yes. CMS assigns special Medicare coverage instructions to Q5110.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Fee sheets · Coming soon
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