Billing code 45333: Flexible sigmoidoscopyMedicare rate & RVUs

Reports flexible sigmoidoscopy with removal of a colorectal lesion using hot biopsy forceps, such as treatment of a polyp found in the examined segment.

CMS RVU26DEffective Oct 1, 2026109 payment localities514 Medicare services in 2024

Medicare pays $368.08 for 45333 nationally in the office and $86.51 in a hospital or facility. Local office rates run $320.76–$507.37.

Medicare rate · 45333

Flexible sigmoidoscopy

Swap in your local Medicare rate.

Work RVUs
1.51
Total RVUs
11.02
Global days
000

National rate · 2026

$368.08

Office setting, before claim adjustments.

See every locality for 45333 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What 45333 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 45333 covers

A flexible sigmoidoscope is advanced through the rectum to examine the lower colon. During the examination, the endoscopist uses hot biopsy forceps to grasp and remove a lesion, commonly a small polyp. Gastroenterologists and other physicians trained in gastrointestinal endoscopy perform this service in settings such as an endoscopy center or hospital outpatient department.

Select this code when the documented removal technique is hot biopsy forceps, rather than tissue sampling alone or removal by snare. The report should identify the examined segment, lesion, and removal method. When related endoscopies are performed in the same session, CMS applies endoscopy-family pricing rather than pricing each service independently. The 0-day global period includes same-day preoperative and postoperative care. Modifier 50 is inappropriate for this anatomy. Assistant-at-surgery payment is barred, and co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 45333 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$320.76 to $507.37

$320.76$414.06$507.37
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

45333 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$326.10$79.73
Alaska*$410.17$110.29
Arizona$357.40$84.56
Arkansas$320.76$78.89
Atlanta$374.67$88.60
Austin$385.34$87.44
Bakersfield$395.95$87.35
Baltimore/Surr. Cntys$393.28$91.15
Beaumont$339.63$83.40
Brazoria$364.07$85.04

45333 rates by state

Office rate range in each state. Select a state to see its payment localities.

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Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$320.76

$451.34

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
45333 office rate range by state
State / territoryOffice rate rangeLocalities
AK$410.171
AL$326.101
AR$320.761
AZ$357.401
CA$395.31–$507.3729
CO$386.931
CT$394.521
DC$426.861
DE$363.861
FL$358.12–$392.043
GA$335.98–$374.672
GU$407.491
HI$407.491
IA$337.271
ID$339.381
IL$345.22–$382.484
IN$341.651
KS$334.641
KY$333.011
LA$332.09–$350.772
MA$383.84–$429.532
MD$371.70–$426.863
ME$340.48–$362.572
MI$342.03–$362.262
MN$371.901
MO$325.07–$353.203
MS$323.031
MT$368.061
NC$344.641
ND$363.711
NE$339.611
NH$379.881
NJ$399.36–$421.402
NM$343.801
NV$367.161
NY$350.38–$436.255
OH$341.141
OK$333.241
OR$364.65–$401.452
PA$342.23–$383.132
PR$371.381
RI$378.481
SC$343.391
SD$363.201
TN$336.441
TX$339.63–$385.348
UT$348.711
VA$360.64–$426.862
VI$371.381
VT$361.341
WA$383.42–$439.692
WI$349.961
WV$330.601
WY$366.171

How the 45333 rate is calculated

Each of 45333’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 45333

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 1.51Practice expense 9.29Malpractice 0.22

11.0200 adjusted RVUs×$33.4009 conversion factor=$368.08

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 45333

The CMS indicators that decide how 45333 is paid alongside other services.

CMS payment indicators · 45333

Flexible sigmoidoscopy

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures3Endoscopy family rules apply.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

45333 without 51 · national office

$368.08

Flexible sigmoidoscopy

45333-51 · Second procedure: 50%

$184.04

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

45333 compared with similar codes

Compare codes

45333 vs 45338 vs 45331 vs 45330: national Medicare rates

Swap in your local Medicare rate.

  • 45333
    Flexible sigmoidoscopy · 1.51 wRVU
    $368.08
  • 45338
    Flexible sigmoidoscopy · 2 wRVU
    $335.01−$33.07
  • 45331
    Sigmoidoscopy · 1.11 wRVU
    $322.99−$45.09
  • 45330
    Flexible sigmoidoscopy · 0.82 wRVU
    $215.10−$152.98

How to choose

45338Flexible sigmoidoscopy
Both report flexible sigmoidoscopy with lesion removal. Choose 45333 for hot biopsy forceps and 45338 when removal is performed with a snare.
45331Sigmoidoscopy
45331 is for biopsy sampling; 45333 is for removal of a lesion using hot biopsy forceps.
45330Flexible sigmoidoscopy
45330 describes a diagnostic flexible sigmoidoscopy without lesion removal. Report 45333 when the examination includes hot-forceps removal.

45333 billing questions

When is this code appropriate instead of a biopsy code?

Use it when the lesion is removed with hot biopsy forceps. A procedure limited to taking tissue for examination is represented by the biopsy service.

How does this differ from snare removal?

This code identifies removal with hot biopsy forceps. Use the snare-removal code when the endoscopist removes the lesion using a snare.

How are related endoscopies in the same session paid?

CMS applies endoscopy-family pricing when related endoscopies are performed together, rather than pricing each as an independent endoscopy.

What documentation supports reporting this service?

Document the flexible sigmoidoscopy, the lesion and its location, and that hot biopsy forceps were used to remove it.

Can modifier 50 or an assistant-at-surgery service be reported?

Modifier 50 is inappropriate for this service. CMS also bars assistant-at-surgery payment and does not permit co-surgeons or team surgery.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 45333PPRRVU2026_Oct_nonQPP.csv, line 5,501 (RVU26D)

Open CMS sourceHow we calculate rates

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