Billing code 46221: Hemorrhoid ligationMedicare rate & RVUs

Reports office or facility treatment of internal hemorrhoids by placing rubber bands around hemorrhoidal tissue to reduce its blood supply.

CMS RVU26DEffective Oct 1, 2026109 payment localities68.8K Medicare services in 2024

Medicare pays $325.66 for 46221 nationally in the office and $197.07 in a hospital or facility. Local office rates run $286.44–$433.20.

Medicare rate · 46221

Hemorrhoid ligation

Swap in your local Medicare rate.

Work RVUs
2.3
Total RVUs
9.75
Global days
010

National rate · 2026

$325.66

Office setting, before claim adjustments.

See every locality for 46221 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What 46221 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 46221 covers

This procedure treats internal hemorrhoids by placing a tight rubber band around the base of hemorrhoidal tissue, typically with an anoscope for visualization. Colorectal surgeons, general surgeons, and gastroenterologists commonly perform it in an outpatient office or facility for symptomatic internal hemorrhoids, such as those causing bleeding or prolapse. The service is for ligation by rubber band, not removal of external hemorrhoids or excision of hemorrhoidal tissue.

Report 46221 for the band-ligation service, including when more than one internal hemorrhoid is treated in the session; document the indication, internal site, technique, and treated tissue. Related postoperative visits for 10 days are included. When other procedures are performed in the same session, the highest-valued procedure is paid in full and the others are subject to the standard multiple-procedure reduction. Modifier 50 is inappropriate. Medicare does not pay an assistant at surgery for this service, and co-surgeon and team-surgery billing are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 46221 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$286.44 to $433.20

$286.44$359.82$433.20
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

46221 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$290.84$178.32
Alaska*$374.06$237.11
Arizona$316.59$191.98
Arkansas$286.44$175.97
Atlanta$332.10$201.44
Austin$338.18$202.12
Bakersfield$345.15$204.21
Baltimore/Surr. Cntys$347.02$209.04
Beaumont$303.49$186.47
Brazoria$321.50$194.06

46221 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$286.44

$388.66

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
46221 office rate range by state
State / territoryOffice rate rangeLocalities
AK$374.061
AL$290.841
AR$286.441
AZ$316.591
CA$344.12–$433.2029
CO$339.101
CT$347.951
DC$373.321
DE$321.991
FL$321.29–$353.753
GA$302.39–$332.102
GU$353.041
HI$353.041
IA$298.281
ID$300.381
IL$311.83–$342.954
IN$302.191
KS$296.961
KY$298.351
LA$297.92–$313.322
MA$337.00–$373.432
MD$328.28–$373.323
ME$302.17–$319.092
MI$306.61–$325.622
MN$324.061
MO$292.67–$314.323
MS$289.601
MT$325.631
NC$305.451
ND$318.521
NE$299.951
NH$333.871
NJ$351.68–$369.212
NM$308.421
NV$323.891
NY$310.25–$385.645
OH$305.151
OK$297.641
OR$321.14–$350.102
PA$305.58–$339.072
PR$328.081
RI$333.631
SC$305.861
SD$317.671
TN$298.541
TX$303.49–$338.188
UT$310.221
VA$318.10–$373.322
VI$328.081
VT$317.351
WA$336.33–$381.062
WI$307.391
WV$299.821
WY$322.531

How the 46221 rate is calculated

Each of 46221’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 46221

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 2.30Practice expense 7.09Malpractice 0.36

9.7500 adjusted RVUs×$33.4009 conversion factor=$325.66

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 46221

46221 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 46221

Hemorrhoid ligation

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 46221

Hemorrhoid ligation

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

46221 without 51 · national office

$325.66

Hemorrhoid ligation

46221-51 · Second procedure: 50%

$162.83

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

46221 compared with similar codes

Compare codes

46221 vs 46930 vs 46945 vs 46255 vs 46250: national Medicare rates

Swap in your local Medicare rate.

  • 46221
    Hemorrhoid ligation · 2.3 wRVU
    $325.66
  • 46930
    Hemorrhoid treatment · 1.57 wRVU
    $247.83−$77.83
  • 46945
    Hemorrhoid ligation · 3.6 wRVU
    —
  • 46255
    Hemorrhoidectomy · 4.84 wRVU
    $580.84+$255.18
  • 46250
    Hemorrhoidectomy · 4.14 wRVU
    $536.75+$211.09

How to choose

46930Hemorrhoid treatment
Use 46221 when internal hemorrhoidal tissue is treated with rubber bands; 46930 describes thermal destruction.
46945Hemorrhoid ligation
Both treat internal hemorrhoids by ligation, but 46945 is for ligation by a method other than rubber-band ligation.
46255Hemorrhoidectomy
46221 is band ligation of internal tissue. 46255 describes excision of an internal and external hemorrhoid group.
46250Hemorrhoidectomy
46250 is excision of multiple external hemorrhoid groups; 46221 treats internal hemorrhoids by rubber-band ligation.

46221 billing questions

Does 46221 cover one band or multiple bands?

The code covers rubber-band ligation of internal hemorrhoid tissue, including when multiple sites are treated in the session. Document the treated internal tissue and technique rather than reporting a separate unit for each band.

How is this different from excisional hemorrhoidectomy?

46221 describes rubber-band ligation of internal hemorrhoids. Codes such as 46255 and 46260 describe excision, with the applicable code depending on the tissue and extent removed.

Are related postoperative visits separately reported?

Related postoperative visits during the 10-day global period are included in 46221.

Can modifier 50 be used when hemorrhoids are treated on both sides?

No. The CMS bilateral adjustment does not apply, and modifier 50 is inappropriate for this service.

How does Medicare handle other procedures performed in the same session?

Under the standard multiple-procedure reduction, the highest-valued procedure is paid in full and the other procedures are paid at 50% when performed in the same session.

Can an assistant or co-surgeon be billed for the ligation?

Medicare does not pay an assistant at surgery for 46221. Co-surgeon and team-surgery billing are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 46221PPRRVU2026_Oct_nonQPP.csv, line 5,581 (RVU26D)

Open CMS sourceHow we calculate rates

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