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Billing code 48400: Pancreatic injectionMedicare rate & RVUs

Reports injection performed during pancreatic surgery to support intraoperative pancreatography, such as evaluating the pancreatic duct during an operative procedure.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $95.19 for 48400 nationally in a facility.

Medicare rate · 48400

Pancreatic injection

Swap in your local Medicare rate.

Work RVUs
1.9
Total RVUs
2.85
Global days
ZZZ

National rate · 2026

$95.19

Facility setting, before claim adjustments.

See every locality for 48400 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What 48400 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 48400 covers

This add-on reports an injection performed during pancreatic surgery to facilitate intraoperative pancreatography, typically by introducing contrast into the pancreatic duct for operative assessment. It is associated with pancreatic operations in which the surgeon needs duct imaging during the procedure; it is not a stand-alone diagnostic pancreatography service performed separately from surgery.

Report 48400 only with the eligible primary procedure performed at the same operative encounter. The operative note should identify the injection, its purpose, and the primary pancreatic procedure; supporting imaging documentation should reflect the intraoperative duct assessment. CMS classifies the service as an add-on and pays it within the primary procedure’s global period, so it cannot be reported as an independent service outside that pairing.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 48400 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

48400 office and facility rates by payment locality
Payment localityOfficeFacility
AlabamaUnavailable$86.17
Alaska*Unavailable$120.57
ArizonaUnavailable$92.36
ArkansasUnavailable$85.09
AtlantaUnavailable$98.92
AustinUnavailable$94.34
BakersfieldUnavailable$91.47
Baltimore/Surr. CntysUnavailable$101.21
BeaumontUnavailable$92.65
BrazoriaUnavailable$91.96

48400 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

View every state and territory as a table
48400 office rate range by state
State / territoryOffice rate rangeLocalities
AKNo published base rate1
ALNo published base rate1
ARNo published base rate1
AZNo published base rate1
CANo published base rate29
CONo published base rate1
CTNo published base rate1
DCNo published base rate1
DENo published base rate1
FLNo published base rate3
GANo published base rate2
GUNo published base rate1
HINo published base rate1
IANo published base rate1
IDNo published base rate1
ILNo published base rate4
INNo published base rate1
KSNo published base rate1
KYNo published base rate1
LANo published base rate2
MANo published base rate2
MDNo published base rate3
MENo published base rate2
MINo published base rate2
MNNo published base rate1
MONo published base rate3
MSNo published base rate1
MTNo published base rate1
NCNo published base rate1
NDNo published base rate1
NENo published base rate1
NHNo published base rate1
NJNo published base rate2
NMNo published base rate1
NVNo published base rate1
NYNo published base rate5
OHNo published base rate1
OKNo published base rate1
ORNo published base rate2
PANo published base rate2
PRNo published base rate1
RINo published base rate1
SCNo published base rate1
SDNo published base rate1
TNNo published base rate1
TXNo published base rate8
UTNo published base rate1
VANo published base rate2
VINo published base rate1
VTNo published base rate1
WANo published base rate2
WINo published base rate1
WVNo published base rate1
WYNo published base rate1

How the 48400 rate is calculated

Each of 48400’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 48400

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 1.90Practice expense 0.46Malpractice 0.49

2.8500 adjusted RVUs×$33.4009 conversion factor=$95.19

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 48400

The CMS indicators that decide how 48400 is paid alongside other services.

CMS payment indicators · 48400

Pancreatic injection

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

48400 compared with similar codes

Compare codes

48400 vs 47563 vs 48102: national Medicare rates

Swap in your local Medicare rate.

  • 48400
    Pancreatic injection · 1.9 wRVU
    —
  • 47563
    Laparoscopic cholecystectomy · 11.18 wRVU
    —
  • 48102
    Pancreatic biopsy · 4.58 wRVU
    $492.66

How to choose

47563Laparoscopic cholecystectomy
This code includes laparoscopic cholecystectomy with intraoperative cholangiography, which evaluates the biliary system. Code 48400 concerns intraoperative pancreatography of the pancreatic duct.
48102Pancreatic biopsy
Code 48102 reports a pancreatic needle biopsy. Code 48400 reports an intraoperative injection for duct imaging and must accompany a primary operation.

Codes related to 48400

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 48400
CodeHow it relatesNational office range
Primary code
48140Pancreas resectionA distal pancreatectomy may be the primary pancreatic operation accompanying intraoperative duct injection.No office rate
48150Whipple procedureA pancreaticoduodenectomy may be the primary operation when intraoperative pancreatography is performed.No office rate
48152PancreatectomyAnother pancreaticoduodenectomy approach that may serve as the primary procedure.No office rate

48400 billing questions

Can 48400 be billed by itself?

No. It is an add-on code and must be reported with an eligible primary procedure for the same operative encounter.

What documentation supports reporting 48400?

Document the intraoperative injection, its purpose in evaluating the pancreatic duct, and the primary pancreatic operation. The record should support that the injection was performed during surgery, not as a separate diagnostic service.

Is 48400 the code for intraoperative cholangiography?

No. It concerns intraoperative pancreatography of the pancreatic duct. Intraoperative cholangiography evaluates the biliary system and is represented by different coding, such as 47563 in the appropriate laparoscopic cholecystectomy setting.

How does the global-period rule affect 48400?

CMS treats this add-on as paid within the primary procedure’s global period. It must be paired with the primary operation rather than reported as an independent service.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 48400PPRRVU2026_Oct_nonQPP.csv, line 5,747 (RVU26D)

Open CMS sourceHow we calculate rates

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